- Medical/Professional School:
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University of Miami - Jackson Memorial Medical Center, Miami
- Residency:
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University of Florida, Gainsville, Pediatrics
- Fellowship:
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Children's Hospital of Alabama, Birmingham, Allergy and Immunology
- Clinical Interests:
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Primary Immunodeficiency Diseases, Hematopoetic Stem Cell Transplantation for Immunodeficiency, Secondary Immunodeficiency associated with Solid Organ Transplantation
Clinical care for patients with primary immunodeficiencies
- Description of Research:
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My clinical research has been focused on the delivery of care and new therapies to patients with primary immunodeficiency diseases, particularly those needing hematopoetic stem cell transplantation. I am particularly interested in how to bring the promise of new therapies currently in the laboratory setting, to reality in the clinical care arena. I also interface with clinicians skilled in the care of solid organ transplant patients who experience secondary immunodeficiency as a consequence of their transplant therapies.
- Key Publications:
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Elder ME, Skoda-Smith S, Kadlecek TA, Wang F, Wu J, Weiss A. Distinct T-cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of Zap-70. (2001) J Immunol 166:656-661.
Skoda-Smith S, Mehta P, Graham-Pole JG, Wingard JR. Treatment of post-transplant lymphoproliferatie disease with induction chemotherapy followed by haploidentical peripheral blood stem cell transplantation and Rituximab. (2001) Bone Marrow Transplantation 27:329-332.
Chun HJ, Zheng L, Ahmad M, Wang J, Speirs CK, Siegel RM, Dale JK, Puck J, Davis J, Hall CG, Skoda-Smith S, Atkinson TP, Strauss SE, Lenardo MJ. Pleiotrophic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. (2002) Nature 419:395-399.
Aranda JM Jr, Scornik JC, Normann SJ, Lottenberg R, Schofield RS, Pauly DF, Miles M, Hill JA, Sleasman JW, Skoda-Smith S. Anti-CD20 monoclonal antibody (rituximab) therapy for acute cardiac vascular rejection: a case report. (2002) Transplantation 73: 907-910.