Skip to main content
On staff since September 2006
Assistant Professor
Center for Integrative Brain Research
Primary office location
R-5417 - Radiology
4800 Sand Point Way NE
Seattle, WA 98105
(206)987-2133
UW Box 357115 - Radiology
1959 NE Pacific St
Seattle, WA 98195-7115
K J Somaiya Medical College, MumbaiL T M G Hospital - University of Mumbai, Mumbai, Radiology
L T M G Hospital - University of Mumbai, Mumbai, Radiology
Children's National Medical Center, Washington, Pediatric RadiologyUniversity of Washington, Seattle, Neuroradiology
Pediatric Neuroimaging Pediatric Craniofacial and Head/Neck Imaging Fetal Neuroimaging
Imaging ScienceNeuroscience / NeurodevelopmentTranslational Research
My research focuses on the application of imaging to the following: 1. Magnetic Resonance Imaging (MRI) of murine medulloblastoma (and other pediatric brain tumor) models in the evaluation of experimental drugs. It has been our goal to use MRI as the end-point for this evaluation and to minimize the use of experimental animals as a consequence. We have also successfully employed a 3 Tesla clinical MRI scanner to obtain substantially high-resolution MR images of juvenile mice. These scanners are generally more accessible than the higher field-strength research magnets and we have fined-tuned basic murine brain imaging sequences, protocols and parameters such that we can use this technique for investigation of murine models of most forms of pediatric (and adult) CNS disease. Various post-processing tools are being employed in the segmentation and volumetric analysis of the imaging data. 2. Craniofacial Imaging of craniosynostosis and craniofacial syndromes in collaboration with the Craniofacial Medicine team at Seattle Children's Hospital. Current research includes: (a) Investigation of metopic synostosis (b) To examine and correlate physical and Computed Tomography (CT) phenotypes and genotypes in patient groups with midface hypoplasia and associated sutural synostoses in non Crouzon's patients using CT in humans and micro-CT in animal models (c) To define physical and CT phenotypes in Oculofrontonasal Syndrome (OAFNS) 3. MRI and Diffusion Tensor Imaging (DTI) and Tractography in the evaluation of trigeminal neuralgia as there is a lack of adequate imaging-clinical correlation using conventional MRI. The hope is that identification of normal and abnormal trigeminal nerve fibers from the nucleus through potentially the three divisions of the nerve may help identify the precise site of abnormality and assist in management of this condition.
Khanna PC, Thapa MM. The growing skeleton: MR appearances of developing cartilage. MRI Clinics of North America 2009; 17 (3): 411-421. Khanna PC, Thapa MM, de Regt D, Weinberger E. PACStacker: An enhancement of Scientific and Educational capabilities of Microsoft PowerPoint. AJR Am J Roentgenol 2009;192:W71-74. Khanna PC, Godinho S, Patkar DP, Pungavkar SA, Lawande MA. Unusual Extra-Axial "Giant" Tuberculoma masquerading as a Meningioma: Diagnostic differentiation with Proton MR Spectroscopy. American Journal of Neuroradiology. 2006; 27(7):1438-40. Lath CO, Khanna PC, Gadewar SB, Patkar DP. Intracranial Metastasis from Prostatic Adenocarcinoma simulating a Meningioma: A case report. Australasian Radiology. 2005; 49(6): 497-500. Khanna PC, Pungavkar SA, Patkar DP. Ultrafast Magnetic Resonance Imaging of Cephalothoracopagus Janiceps Disymmetros. Journal of Postgraduate Medicine. 2005; 51(3): 228-229. Khanna PC, Godinho S, Pungavkar SA, Patkar DP. Ultrafast MRI in the prenatal diagnosis of Bourneville?s Tuberous Sclerosis. Neurology India. 2005; 53(3): 349-350. Khanna PC, Lath CO, Gadewar SB, Patkar DP. Role of Magnetic Resonance Perfusion studies in Moyamoya Disease. A case report. Neurology India. 2004; 52(2): 243-245. Listed on amazon.com by the Owlcroft English-Language site for English usage and grammar. Gomez-Lobo V, Burch W, Khanna PC. Nonpuerperal uterine inversion associated with an immature teratoma of the uterus in an adolescent. Obstet Gynecol 2007; 110(2):491-3. Khanna PC, Ponsky T, Zagol B, Lukish JR, Markle BM. Canal of Nuck hydrocele: Case report and spectrum of sonographic appearances. Pediatric Radiology 2007 37(6):603-606. Epub 2007 Apr 24. Khanna PC, Rothenbach P, Guzzetta P, Bulas DI. Lap-belt Syndrome: Constellation of injuries in a 7-year-old. Pediatric Radiology. 2007; 37 (1):87-90. Epub 2006 Oct 21.
Name:
Dr. Dimitri Christakis comments on a new study that examined the impact of educational DVDs on babies’ language ... cont.
Dr. Wendy Sue Swanson comments on the latest guidelines for car seat safety.
Dr. Sheela Sathyanarayana offers tips on bisphenol A (BPA).
Create a secure profile on Seattle Children's Web site to start saving, organizing, and sharing the content that matters most to you.
Sign in Assistance
This page has been saved to My Organizer.
Visit My Organizer
Return to My Saved Items
Are you sure you want to remove this page from your saved items?
You may find and save this page again at any time.