- Medical/Professional School:
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University of California San Francisco School of Medicine, San Francisco
University of California Berkeley, Berkeley
- Residency:
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Yale-New Haven Hospital, New Haven, Urology
- Fellowship:
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University of Washington School of Medicine, Seattle, Pediatric Urology
- Clinical Interests:
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crytorchidism
prenatal hydronephrosis
urogenital reconstruction
- Description of Research:
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Ifosfamide, an alkalating agent structurally related to cyclophosphamide, is a newer chemotherapeutic agent whose toxicity profile has not been well studied. The hypothesis is that ifosfamide impairs fertility.
The main study airs include:
a) determine the toxicity profile by identifying the doses which increase risk of infertility;
b) identifying protective germ cell line polymorphisms in patients exposed to ifosfamide;
c) potential intermediate biomarkers of infertility in this group.
I will gather questionnaire data (regarding erectile dysfunction and infertility), biochemical evaluation, DNA analysis, and semen samples.
- Key Publications:
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Hidalgo-Tamola J, Shnorhavorian M, Koyle MA. "Open" minimally invasive surgery in pediatric urology. "J of Pediatric Urology", March, 2009
Shnorhavorian M, Friedman DL and Koyle MA. Genitourinary long-term outcomes for childhood cancer survivors. "Current Urology Reports", March, 2009, Vol. 10(2): 134-7
Shnorhavorian M, Grady RW, Anderson A, Joyner BD, Mitchell ME: Long-term follow-up of complete primary repair of exstrophy: the Seattle experience. "J Urol", 180 (4 Suppl):1615-9; discussion 1619-20, October, 2008
Shnorhavorian M, Friedman D, Koyle MA. Genitourinary long-term outcomes for childhood cancer survivors. Dialogues in "Pediatric Urology". Vol. 29(6); August, 2008
Lendvay TS, Shnorhavorian M, Grady RW: Robotic-assisted laparoscopic Mitrofanoff appendicovesicostomy and antegrade continent enema colon tube creation in a pediatric spina bifida patient. "J Laparoendosc Adv Surg Tech": 18(2); 310-2, April, 2008
- Honors & Awards:
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1995: Phi Beta Kappa Honor Society
1996: Dean's Award for Summer Research, UCSF School of Medicine
2000: Ira S. Goldberg House Staff Award for Outstanding Intern, Yale School of Medicine
2007: Clinical Research Award, American Academy of Pediatrics, Section on Urology, National Conference
2008: Third Prize Award, American Urological Association, Western Section, "Pediatric Vaginal Trauma: Variability in Evaluation and Management Across Free-standing Pediatric Hospitals in the United States."
2008-Present: National Institutes of Health, Child Health and Development, Male Reproductive Health Research Award
2008-Present: Member, Children's Oncology Group (COG): Survivorship Task Force, Surgery Task Force, Testes Task Force, and Late Urinary Effects Committee