- Board Certified:
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General Pediatrics (Non-ABMS)
Neonatal-Perinatal (Non-ABMS)
Pediatric Endocrinology (Non-ABMS)
- Medical/Professional School:
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Ruprechts-Karls-Universitat, Heidelberg
- Residency:
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University of Gottingen, Gottingen, Pediatrics
- Fellowship:
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University of Gottingen, Gottingen, Pediatric Endocrinology
- Clinical Interests:
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Clinical Interests: Children with endocrine disorders and diabetes mellitus
Research Interests: Obesity studies, including appetite-regulating peptides, factors of the metabolic syndrome, hypothalamic obesity and genetic and environmental factors involved in the onset of puberty
- Research Focus Area:
Diabetes
Endocrinology / Metabolism
Biochemistry
- Description of Research:
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My research is focused on childhood obesity, diabetes and puberty. It includes metabolic factors in body weight regulation and hypothalamic control of feeding circuits, genes involved in childhood obesity and diabetes, and post-craniopharyngioma obesity. On the field of puberty, I am working on treatment of precocious puberty and genes controllng the onset of puberty.
- Key Publications:
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Roth CL, Mastronardi C, Lomniczi A, Wright H, Cabrera R, Mungenast AE, Heger S, Jung H, Dubay C, Ojeda SR (2007) Expression of a tumor related gene network increases in the mammalian hypothalamus at the time of female puberty. Endocrinology 148:5147-5161
Roth CL, Hunneman DH, Gebhardt U, Stoffel-Wagner B, Reinehr T, Muller HL (2007) Reduced sympathetic metabolites in urine of obese patients with craniopharyngioma. Pediatr Res 61:496-501.
Roth CL, Enriori P, Harz K, Woelfle J, Cowley MA, Reinehr T (2005) Peptide YY is a regulator of energy homeostasis in obese children before and after weight loss. J Clin Endocrinol Metab 90:6386-6391
Roth C, Hegemann F, Hildebrandt J, Balzer I, Witt A, Wuttke W, Jarry H (2004) Pituitary and gonadal effects of GnRH (gonadotropin releasing hormone) analogues in two peripubertal female rat models. Pediatr Res 55: 126-133
Roth C, Schmidberger H, Schaper O, Leonhardt S, Lakomek M, Wuttke, Jarry H (2000) Cranial irradiation of female rats causes dose- and age-dependent activation or inhibition of pubertal development. Pediatr Res 47, 586-591
- Honors & Awards:
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Henning-Andersen-Award 2004, European Society for Paediatric Endocrinology (ESPE).
Jurgen-Bierich-Award 2002 , German Society for Pediatric Endocrinology (APE)
Winner of the Award 2000 of the German Society for Pediatric and Adolescent Gynecology