Charles Vincent (Skip) Smith, PhD

Professional History

Research Focus Area:

Tissue Response to Injury
Diabetes

Description of Research:

My research is directed at defining the molecular mechanisms of cell and tissue damage, to provide a foundation for rational approaches to the prevention, treatment, or use of cell damage to enhance human health.

Key Publications:

Yang C-y, Chen H-H, Huang MT, Raya JL, Yang J-H, Chen C-H, Gaubatz JW, Pownall HJ, Taylor AA, Ballantyne CM, Jenniskens FJ, and Smith CV. Pro-apoptotic low-density lipoprotein subfractions in type II diabetes. Atherosclerosis, in press, 2006.

Smith CV. Compartmentalization of redox regulation of cell responses. Toxicol Sci 83:1-3, 2005.

Rogers LK, Tamura T, Rogers BJ, Hansen TN, Welty SE, and Smith CV. Analyses of glutathione reductase hypomorphic mice indicate a genetic knock-out. Toxicol Sci, 82: 367-373, 2004.

Yang C-y, Wang J, Krutchinsky AM, Chait BT, Morrisett JD, and Smith CV. Selective oxidation in vitro by myeloperoxidase of the N-terminal amine in apolipoprotein B-100. J Lipid Res 42: 1891-1896, 2001.

Smith CV. Correlations and apparent contradictions in assessment of oxidant stress status in vivo. Free Rad Biol Med 10: 217-224, 1991.

Honors & Awards:

1992: Traveling Lectureship; ICI, Ltd.