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Roja Motaghedi, MD

Roja Motaghedi, MD


On staff since August 2012


Board Certification(s)
Pediatric Endocrinology
Medical/Professional School
Islamic Azad University, Tehran, Iran
Pediatrics, Maimonides Medical Center, Brooklyn
Pediatric Endocrinology, Weill Cornell Medical College - New York Presbyterian, New York
Clinical Interests

Disorders of puberty, thyroid and growth; obesity and metabolic syndrome

Research Description

Obesity and diabetes


Anti-cytokine autoantibodies preceding onset of autoimmune polyendocrine syndrome type I features in early childhood.
Journal of clinical immunology , 2013 Nov: 33(8)1341-8
Association of Obesity With Inflammation and Pain After Total Hip Arthroplasty.
Clinical orthopaedics and related research , 2013 Oct 5
Whole-exome sequencing identifies novel LEPR mutations in individuals with severe early onset obesity.
Obesity (Silver Spring, Md.) , 2013 Apr 24
Metformin monotherapy in youth with recent onset type 2 diabetes: experience from the prerandomization run-in phase of the TODAY study.
Pediatric diabetes , 2012 Aug: 13(5)369-75
Determinants of glycemic control in youth with type 2 diabetes at randomization in the TODAY study.
Pediatric diabetes , 2012 Aug: 13(5)376-83
A clinical trial to maintain glycemic control in youth with type 2 diabetes.
The New England journal of medicine , 2012 Jun 14: 366(24)2247-56
The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans.
The Journal of clinical investigation , 2011 Sep: 121(9)3635-44
Psychiatric adverse effects of rimonobant in adults with Prader Willi syndrome.
European journal of medical genetics , 2011 Jan-Feb: 54(1)14-8
Large islets, beta-cell proliferation, and a glucokinase mutation.
The New England journal of medicine , 2010 Apr 8: 362(14)1348-50
Screening markers of impaired glucose tolerance in the obese pediatric population.
Hormone research in paediatrics , 2010: 73(2)102-7
Autoimmune type I diabetes mellitus in a perinatally HIV infected patient with a well-preserved immune system.
Journal of pediatric endocrinology & metabolism : JPEM , 2009 Apr: 22(4)369-72
IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans.
Immunity , 2008 Nov 14: 29(5)746-57
The CB1 endocannabinoid system modulates adipocyte insulin sensitivity.
Obesity (Silver Spring, Md.) , 2008 Aug: 16(8)1727-34
Insulin-like growth factor binding protein-1 to screen for insulin resistance in children.
Diabetes technology & therapeutics , 2007 Feb: 9(1)43-51
Childhood obesity and insulin resistance.
Cell biochemistry and biophysics , 2007: 48(2-3)73-8
Update on the prenatal diagnosis and treatment of congenital adrenal hyperplasia due to 11beta-hydroxylase deficiency.
Journal of pediatric endocrinology & metabolism : JPEM , 2005 Feb: 18(2)133-42

Primary Office

Seattle Children's
OC.7.820 - Endocrinology
4800 Sand Point Way NE
Seattle, WA 98105

Additional Offices

Seattle Children's Bellevue Clinic and Surgery Center
1500 - 116th Ave NE
Bellevue, WA 98004
Seattle Children's Olympia
CO - Suite 140
615 Lilly Rd NE
Olympia, WA 98506

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