Kendra M. Smith, MD

Kendra M. Smith, MD


On staff since February 2001

Children's Title: Member Extracorporeal Life Support Steering Committee, Co-Medical Director Seattle Children's ICU Transport Team

Academic Title: Clinical Associate Professor of Pediatrics

Research Center: Center for Developmental Therapeutics

Dr. Smith’s focus in research historically has been in lung injury prevention in the preterm and term neonate. She has studied ventilator techniques and different ventilation support modalities and currently is working clinically on strategies to minimize lung trauma in infants requiring ventilation due to respiratory failure at birth in very sick preterm and term infants and particularly in infants with congenital diaphragmatic hernia.

Because of this interest she serves as the Manager of Divisional Respiratory Care Programs with the goal of promoting improved ventilation strategies for neonates requiring ventilatory support in our region. Dr. Smith also is involved in the extracorporeal life support (ECLS) program for neonates and serves on the ECLS Steering Committee, which focuses on improving techniques to maximally support newborn infants with severe respiratory failure not responsive to conventional ventilatory therapies. Dr. Smith is co-Medical Director of the Children’s Ground Transport Team and serves as an advisor for Airlift Northwest’s neonatal transports.


  • Erin Missoula, MT 12.02.10

    My husband and I strongly recommend Dr. Smith as an incredibly knowledgable, compassionate doctor. We truly felt that Dr. Smith was treating our daughter as if she were her own daughter. Thank you so much.


Board Certification(s)

Neonatal-Perinatal Medicine

Medical/Professional School

University of Minnesota , Minneapolis


Pediatrics, University of Minnesota , Minneapolis


Neonatal-Perinatal Medicine, University of Minnesota , Minneapolis

Clinical Interests

Potential effects of narcotics and sedatives on the developing brain, Family centered care, Parent brochures reviewing information on problems infants can have in the newborn period


  • Kendra M. Smith, MD
    Is age at initiation of extracorporeal life support associated with mortality and intraventricular hemorrhage in neonates with respiratory failure?
    J Perinatol , 2014 : 34(5)386-391
  • McMullan DM, Thiagarajan RR, Smith KM, Rycus PT, Brogan TV
    Extracorporeal cardiopulmonary resuscitation outcomes in term and premature neonates*.
    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2014 Jan. : 15(1)e9-e16
  • Kendra M. Smith, MD
    Extracorporeal life support in neonates
    Neonatology, 7th edition , 2013


Presentations Title Event Location Date
Use of the IPad for direct MCP consultation on transport HIMSS and Seattle Children's Mobile Health Tech Talk Seattle, WA March 26, 2014
Volume Guarantee: Facts, Strategies and Case Studies in Neonatal Ventilation CCANN Conference "New Horizons in Neonatal Pulmonary Care Childrens Hospital of Central California, Madera, CA April 27, 2013
Lines, Loops and Lessons Learned, Ventilating the Critically Ill Newborn Annual Dr. Enok Lohne Memorial Current Concepts and Innovations in Respiratory Care Madera, CA April 26, 2013
Lines, Loops and Lessons Learned Alta Bates Hospital Oakland, CA Feb. 21, 2012

Research Funding

Grant Title Grantor Amount Award Date
A multi-center, randomized, placebo-controlled, double-blind, two-armed, parallel group study to evaluate efficacy and safety of IV Sildenafil in the treatment of neonates with persistent pulmonary hypertension of the newborn or hypoxic respiratory failure and at risk for persistent pulmonary hypertension, with a long term follow-up investigation of developmental progress 12 and 24 months after completion of study treatment. Pfizer Pharmaceutical Company $51,827
Partial liquid ventilation for lung protection in congenital diaphragmatic hernia (CDH) patients on ECLS Seattle Childrens Hospital -Academic Enrichment Fund $50,000