Heather Louise Schuback, MD

Heather Louise Schuback, MD

Cancer and Blood Disorders Center, Apheresis

On staff since July 2013

Children's Title: Co-Medical Director of Acute Care Oncology, Division of Pediatric Hematology, Oncology, Bone Marrow transplant and Cellular Therapy

Academic Title: Clinical Assistant Professor

"I enjoy interacting with patients and their families and understanding what is most important to them throughout their treatment. As a young adult cancer survivor, I understand the physical, emotional, and long-term consequences of cancer therapy. I feel fortunate to work at a center like Seattle Children’s Hospital that is on the forefront of developing new therapies to improve the outcome and reduce toxicity for children and young adults with cancer. "

  • Biography

    Dr. Schuback is an attending physician at Seattle Children’s Hospital and a clinical assistant professor of pediatrics at the University of Washington School of Medicine.  Her interests include high risk leukemia and lymphoma, bone marrow transplant, fertility preservation and resident teaching. Dr. Schuback’s previous research focused on improving risk stratification in pediatric acute myeloid leukemia (AML). She is currently active in clinical research to improve the quality of care of hospitalized patients.

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  • Awards and Honors

    Award Name Award Description Awarded By Award Date
    American Society of Hematology Abstract Award American Society of Hematology 2012

  • Publications

    Other Publications

    • Farrar JE, Schuback HL, Ries RE, Wai D, Hampton OA, Trevino LR, Alonzo TA, Guidry Auvil JM, Davidsen TM, Gesuwan P, Hermida L, Muzny DM, Dewal N, Rustagi N, Lewis LR, Gamis AS, Wheeler DA, Smith MA, Gerhard DS, Meshinchi S
      Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse.
      26941285 Cancer research, 2016 Apr 15 : 76(8)2197-205 PMCID:PMC4873364
    • Schuback HL, Arceci RJ, Meshinchi S
      Somatic characterization of pediatric acute myeloid leukemia using next-generation sequencing.
      24246700 Seminars in hematology, 2013 Oct. : 50(4)325-32

  • Presentations

    Presentation Title Event Location Date
    CBFA2T3-GLIS2 fusion is Prevalent in Younger Patients with Acute Myeloid Leukemia and Associated with High Risk of Relapse and Poor Outcome: A Children’s Oncology Group Report American Society of Hematology 2014
    Genome Wide Promoter Methylation Patterns Predict AML Subtype Outcomes and Identify Novel Pathways Characterizing Diagnostic and Relapsed Disease in Children American Society of Hematology 2012
    Clinically Significant Mutations, Deletions and Translocations involving ETV6 identified by Whole Genome and Whole Exome Sequencing: Report From NCI/COG Target AML Initiative American Society of Hematology 2012
    Identification of Novel Somatic Mutations, Regions of Recurrent Loss of Heterozygosity (LOH) and Significant Clonal Evolution from Diagnosis to Relapse in Childhood AML Determined by Exome Capture Sequencing- an NCI/COG Target AML Stud American Society of Hematology 2012

  • Research Funding

    Grant Title Grantor Amount Award Date
    ASCO Conquer Cancer Foundation Young Investigator Award ASCO Conquer Cancer Foundation/Strike 3 2013
    St. Baldrick's Fellow Award St. Baldrick's 2013
    Alex's Lemonade Stand Foundation Young Investigator Award Alex's Lemonade Stand Foundation 2013

Overview

Board Certification(s)

Pediatrics

Medical/Professional School

University of Utah School of Medicine, Salt Lake City, UT

Residency

Michigan State University College of Human Medicin, East Lansing, MI

Fellowship

Michigan State University at Grand Rapids, Grand Rapids, MI
Seattle Children's Hospital, Seattle, WA

Clinical Interests

Leukemia and lymphoma; HSCT; Childhood AML