Profile

Daniela Luquetti, MD, PhD

Daniela Luquetti, MD, PhD

Craniofacial

Academic Title: Assistant Professor

Research Center: Center for Developmental Biology and Regenerative Medicine

Daniela V Luquetti, MD, PhD, is an Assistant Professor in the Department of Pediatrics at the University of Washington School of Medicine. She completed her medical geneticist training in 2005 and her PhD in Publich Health in 2009. Dr. Luquetti's research focuses on the genetic and non-genetic risk factors of craniofacial conditions.

Dr. Luquetti has a broad background in medical genetics and epidemiology, with specific training and experience in birth defects. As a doctorate student, she conducted birth defects surveillance research and secondary data analysis on epidemiological aspects of birth defects. As a postdoctoral fellow in the Division of Craniofacial Medicine at the University of Washington, she has expanded her research to include the assessment of genetic sequence variation as well as other potential genetic causes of birth defects. She is currently studying genetic and non-genetic risk factors for microtia (underdevelopment of the external ear).

Making A Difference

Overview

Medical/Professional School

Federal University of Uberlandia, Uberlandia, Minas Gerais
Oswaldo Cruz Foundation (FIOCRUZ), Rio De Janeiro

Residency

Medical Genetics, University of Campinas - Brazil, Campinas

Fellowship

Craniofacial Medicine, University of Washington, Seattle

Research Description

Craniofacial disorders, Microtia, Birth Defects, Epidemiology, Genetics, South American populations

Lab URL

http://www.seattlechildrens.org/research/developmental-biology-regenerative-medicine/luquetti-lab/

Awards and Honors

Award Name Award Description Awarded By Award Date
Grade A PhD Student Outstanding PhD student award. Foundation for Research Support of Rio de Janeiro State Sept. 2008 - June 2008
Scholarship Granted a scholarship to pursue further training/experience in the US during PhD. Foundation for the Coordination of Higher Education and Graduate Training, Ministry of Education, Brazil March 2008 - Aug. 2008

Publications

  • Luquetti DV, Saltzman BS, Lopez-Camelo J, Dutra Mda G, Castilla EE
    Risk factors and demographics for microtia in South America: a case-control analysis.
    Birth defects research. Part A, Clinical and molecular teratology , 2013 Nov. : 97(11)736-43
  • Luquetti DV, Saltzman BS, Sie KC, Birgfeld CB, Leroux BG, Evans KN, Smartt JM Jr, Tieu DD, Dudley DJ, Heike CL
    Interrater reliability of a phenotypic assessment tool for the ear morphology in microtia.
    American journal of medical genetics. Part A , 2013 June : 161A(6)1264-72
  • Birgfeld CB, Saltzman BS, Luquetti DV, Latham K, Starr JR, Heike CL
    Comparison of two-dimensional and three-dimensional images for phenotypic assessment of craniofacial microsomia.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association , 2013 May : 50(3)305-14
  • Luquetti DV, Hing AV, Rieder MJ, Nickerson DA, Turner EH, Smith J, Park S, Cunningham ML
    "Mandibulofacial dysostosis with microcephaly" caused by EFTUD2 mutations: expanding the phenotype.
    American journal of medical genetics. Part A , 2013 Jan. : 161A(1)108-13
  • Luquetti DV, Saltzman BS, Vivaldi D, Pimenta LA, Hing AV, Cassell CH, Starr JR, Heike CL
    Evaluation of ICD-9-CM codes for craniofacial microsomia.
    Birth defects research. Part A, Clinical and molecular teratology , 2012 Dec. : 94(12)990-5
  • Quina LA, Kuramoto T, Luquetti DV, Cox TC, Serikawa T, Turner EE
    Deletion of a conserved regulatory element required for Hmx1 expression in craniofacial mesenchyme in the dumbo rat: a newly identified cause of congenital ear malformation.
    Disease models & mechanisms , 2012 Nov. : 5(6)812-22
  • Birgfeld CB, Saltzman BS, Luquetti DV, Latham K, Starr JR, Heike CL
    Comparison of Two-Dimensional and Three-Dimensional Images for Phenotypic Assessment of Craniofacial Microsomia.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association , 2012 July 31
  • Luquetti DV, Heike CL, Hing AV, Cunningham ML, Cox TC
    Microtia: Epidemiology and genetics.
    American journal of medical genetics. Part A , 2011 Nov. 21
  • Luquetti DV, Leoncini E, Mastroiacovo P
    Microtia-anotia: a global review of prevalence rates.
    Birth defects research. Part A, Clinical and molecular teratology , 2011 Sept. : 813-22
  • Birgfeld CB, Luquetti DV, Gougoutas AJ, Bartlett SP, Low DW, Sie KC, Evans KN, Heike CL
    A phenotypic assessment tool for craniofacial microsomia.
    Plastic and reconstructive surgery , 2011 Jan. : 313-20
  • Luquetti DV, Koifman RJ
    Surveillance of birth defects: Brazil and the US.
    Ciencia & saude coletiva , 2011 : 777-85
  • Luquetti DV, Koifman RJ
    Validity and reliability of the Brazilian birth certificate for reporting birth defects.
    Journal of registry management , 2010 : 112-20
  • Luquetti DV, Koifman RJ
    Quality of reporting on birth defects in birth certificates: case study from a Brazilian reference hospital.
    Cadernos de saude publica / Ministerio da Saude, Fundacao Oswaldo Cruz, Escola Nacional de Saude Publica , 2009 Aug. : 1721-31
  • Lonardo F, Sabba G, Luquetti DV, Monica MD, Scarano G
    Al-Awadi/Raas-Rothschild syndrome: two new cases and review.
    American journal of medical genetics. Part A , 2007 Dec. 15 : 3169-74
  • Della Monica M, Lonardo F, Faravelli F, Pierluigi M, Luquetti DV, De Gregori M, Zuffardi O, Scarano G
    A case of autism with an interstitial 1q deletion (1q23.3-24.2) and a de novo translocation of chromosomes 1q and 5q.
    American journal of medical genetics. Part A , 2007 Nov. 15 : 2733-7
  • Lonardo F, Parenti G, Luquetti DV, Annunziata I, Della Monica M, Perone L, De Gregori M, Zuffardi O, Brunetti-Pierri N, Andria G, Scarano G
    Contiguous gene syndrome due to an interstitial deletion in Xp22.3 in a boy with ichthyosis, chondrodysplasia punctata, mental retardation and ADHD.
    European journal of medical genetics , 2007 July : 301-8
  • Luquetti DV, Oliveira-Sobrinho RP, Gil-da-Silva-Lopes VL
    Gillespie syndrome: additional findings and parental consanguinity.
    Ophthalmic genetics , 2007 June : 89-93
  • Cavalcanti DP, Matejas V, Luquetti D, Mello MF, Zenker M
    Fraser and Ablepharon macrostomia phenotypes: concurrence in one family and association with mutated FRAS1.
    American journal of medical genetics. Part A , 2007 Feb. 1 : 241-7
  • Gil-da-Silva-Lopes VL, Luquetti DV
    Congenital temporomandibular joint ankylosis: clinical characterization and natural history of four unrelated affected individuals.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association , 2005 Nov. : 694-8

Research Funding

Grant Title Grantor Amount Award Date
CFM: Longitudinal Outcomes in Children pre-Kindergarten (CLOCK) NIH NIDCR $2,730,156 2012 - 2017
Phenotypic and Genomic Characterization of Microtia in the Andean Population NIH NIDCD $700,979 2011 - 2016