Skip to main content

Search
Profile

Akiko Shimamura, MD, PhD

|
Akiko Shimamura, MD, PhD

Hematology-Oncology

On staff since July 2007

Research Center: Center for Clinical and Translational Research

"Bone marrow failure is rare, so families often come to us not knowing whats wrong with their child. It makes a big difference when you can tell families and patients that this is what you have and this is what were going to do to try to make things better. It provides a sense of relief and hope. I like working with these patients because they deserve the same commitment to the best medical care as patients with more common diseases. The scientific advances from the study of marrow failure have deepened our understanding of blood diseases and cancers in the general population as well. I learn something new with every patient."

Recommendations

GingerMonroe, WA04.26.11
Dr. Shimamura is a kind, caring, compassionate doctor. She has taken time to explain my child's disease to her in an age-appropriate manner without being patronizing. She also communicates well with me on a highly technical level. She also helps my child understand that she is expected to become more involved with owning her own care as she transitions to adulthood, and that resources are going to be available for her as and adult through the SCA and the UW Medical Center. We are so very fortunate to have one of the world's top authorities on Fanconi Anemia here in the Northwest.
Recommend Dr. Akiko Shimamura

Overview

Board Certification(s)
Pediatric Hematology-Oncology
Medical/Professional School
University of Rochester School of Medicine, Rochester
Johns Hopkins University School of Medicine, Baltimore
Residency
Pediatrics, Johns Hopkins University School of Medicine, Baltimore
Fellowship
Pediatric Hematology-Oncology, Children's Hospital Boston, Boston
Pediatric Hematology-Oncology, Children's Hospital Boston, Boston
Clinical Interests

Inherited bone marrow failure syndromes and aplastic anemia Shwachman-Diamond syndrome, Fanconi anemia and Diamond Blackfan anemia

Research Description

My research interests focus on hematopoiesis and leukemogenesis in the inherited marrow failure syndrome. My current studies investigate the role of ribosomal dysfunction in marrow failure and malignant transformation. I am also pursuing studies on translational control of gene expression in hematopoietic stem cells. Recent laboratory findings reported a role for mitotic spindle stabilization in genomic instability. I am a member of the scientific advisory board for the Shwachman-Diamond Syndrome Foundation and served as co-chair of the Fourth International Scientific Congress on Shwachman-Diamond Syndrome. I am also the principal investigator for the North American Shwachman-Diamond Syndrome Registry currently under development.

Research Focus Area

Cancer, Blood Disorders

Awards and Honors

Award NameAward DescriptionAwarded ByAward Date
Rare Disease Research Hall of Famehttp://rarediseaseday.us/meet-the-community/researche-hall-of-fame/National Organization for Rare Diseases (NORD) 2013
U.S. News Top DoctorU.S. News and World Report 2012
Seattle Top Doctors (Hematology),Seattle Magazine 2011
Golden Stethoscope Award (Hematology),Seattle Magazine 2010
"Guide to America's Top Pediatricians"Consumer's Research Council of America 2009
Harvard Medical School Scholars in Medicine Award 2000
V Foundation Scholar 1997
Howard Hughes Medical Institute Physician Fellow 1997
Amy Clare Potter Fellowship 1997
David Abraham Fellowship 1997
The Robert Kates Award(for excellence in clinical medicine and research) 1991
Alpha Omega Alpha 1990
Holtfreter Fellowship (for outstanding graduate work) 1986
Phi Beta Kappa 1983

Publications

Inherited Aplastic Anemia Syndromes
In: Greer, J.P., Arber D.A., Glader, B.E., List, A.F., Means, R.T., Paraskevas, F., Rodgers, G.M., Foerster, J., eds. Wintrobe's Clinical Hematology. 13th ed. Philadelphia: Lippincott Williams and Wilkins , 2014
Variable Clinical Presentation of Shwachman-Diamond Syndrome: Update from the North American Shwachman-Diamond Syndrome Registry.
The Journal of Pediatrics , Dec. 2013
Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): An initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC).
Pediatric blood and cancer , Nov. 2013
Common variable immunodeficiency as the initial presentation of dyskeratosis congenita.
The Journal of allergy and clinical immunology , July 2013: 132(1)223-6
Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction.
Cell stem cell , June 2013: 12(6)727-36
H/ACA small RNA dysfunctions in disease reveal key roles for noncoding RNA modifications in hematopoietic stem cell differentiation.
Cell reports , May 2013: 3(5)1493-502
Clinical and molecular pathophysiology of Shwachman-Diamond syndrome: an update.
Hematology/oncology clinics of North America , Feb. 2013: 27(1)117-28, ix
Shwachman-Diamond Syndrome
In Clincial Decision Support: Hematology, edited by Benz E.J., Berliner, N., Brodsky, R, LaCasce, A., Moake, J. Decision Support in Medicine, LLC. Wilmington, DE www.decisionsupportinmedicine.com , 2013
Fanconi Anemia
In Clinical Decision Support: Hematology, edited by Benz E.J., Berliner, N., Brodsky R., LaCasce A., Moake J. Decision Support in Medicine, LLC. Wilmington, DE www.decisionsupportinmedicine.com , 2013
ComprehensiveGenomic Evaluation for Inherited Bone Marrow Failure and Myelodysplastic Syndromes
American Society of Hematology , 2013
Translational Profiling Reveals the elF2 kinase Pathway as a Mediator of Dexamethason Induced Apoptosis in Multiple Myeloma
American Society of Hematology , 2013
Impaired ribosomal subunit association in Shwachman-Diamond syndrome.
Blood , Dec. 2012: 120(26)5143-52
Breast cancer in a case of Shwachman Diamond syndrome.
Pediatric blood and cancer , Nov. 2012: 59(5)945-6
Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature.
Blood , Feb. 2012: 119(5)1283-91
Draft consensus guidelines for diagnosis and treatment of Shwachman-Diamond syndrome.
Annals of the New York Academy of Sciences , Dec. 2011: 124240-55
Fanconi anemia-like presentation in an infant with constitutional deletion of 21q including the RUNX1 gene.
American journal of medical genetics. Part A , July 2011: 155A(7)1673-9
A simulation-based comparison of two methods for determining relaxation rates from relaxometry images.
Magnetic resonance imaging , May 2011: 29(4)497-506
Non-Diamond Blackfan anemia disorders of ribosome function: Shwachman Diamond syndrome and 5q- syndrome.
Seminars in hematology , April 2011: 48(2)136-43
Clinical spectrum and molecular pathophysiology of Shwachman-Diamond syndrome.
Current opinion in hematology , Nov. 2010
SBDS protein expression patterns in the bone marrow.
Pediatric blood and cancer , Sept. 2010: 546-9
Stable long-term risk of leukaemia in patients with severe congenital neutropenia maintained on G-CSF therapy.
British journal of haematology , July 2010: 196-9
Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1.
Stem cells (Dayton, Ohio) , July 2010: 28(7)1186-95
Pathophysiology and management of inherited bone marrow failure syndromes.
Blood reviews , May 2010: 101-22
Knockdown of Fanconi anemia genes in human embryonic stem cells reveals early developmental defects in the hematopoietic lineage.
Blood , April 2010: 3453-62
Congenital disorders of ribosome biogenesis and bone marrow failure.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation , Jan. 2010: S12-7
Clinical approach to marrow failure.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program , 2009: 329-37
TERC and TERT gene mutations in patients with bone marrow failure and the significance of telomere length measurements.
Blood , Jan. 2009: 309-16
Acquired Aplastic Anemia and Pure Red Cell Aplasia
In: Nathan, D.G., Orkin, S.H., Look, A.T., Ginsburg, D. Fisher, DE and Lux, SE, editors. Nathan and Oski's Hematology of Infancy and Childhood, 7th Edition; Philadelphia: W.B. Saunders and Co. , 2009: 275-306
Inherited Aplastic Anemia Syndromes
In: Greer, J.P., Foerster, J., Rodgers, G.M., Paraskevas, F., Glader, B.E., Arber DA, Means, RT eds. Wintrobe's Clincial Hematology. 12th ed. Philadelphia: Lippincott Williams and Wilkins , 2009: 1173-1184
Shwachman-Diamond Syndrome: A review of the clinical presentation, molecular pathogenesis, diagnosis, and treatment
Hemmatol Oncol Clin North Am. Editor: Bagby, G. , 2009: 23233-248
Diamond-Blackfan anemia: a new facet.
Blood , Sept. 2008: 1552-3
Disease-specific induced pluripotent stem cells.
Cell , Sept. 2008: 877-86
Diagnosing and treating Diamond Blackfan anaemia: results of an international clinical consensus conference.
British journal of haematology , Sept. 2008: 859-76
Expression of the Shwachman-Bodian-Diamond syndrome (SBDS) protein in human pancreatic cancer and chronic pancreatitis.
Histology and histopathology , July 2008: 819-26
Ribosomal dysfunction and inherited marrow failure.
British journal of haematology , May 2008: 376-87
Mitotic spindle destabilization and genomic instability in Shwachman-Diamond syndrome.
The Journal of clinical investigation , April 2008: 1511-8
Inherited Aplastic Anemia Syndromes
In: Greer, J.P., Foerster, J., Rodgers, G.M., Paraskevas, F., Glader, B.E., Arber DA, Means, RT eds. Wintrobe's Clinical Hematology. 12th ed. Philadelphia; Lippincott Williams and Wilkins , 2008: 1173-1184
"Treatment of Hematological Abnormalities in Fanconi Anemia" In Fanconi Anemia: Standards for Clinical Care, Fanconi Anemia Research Fund
, 2008: 49-75
The human Shwachman-Diamond syndrome protein, SBDS, associates with ribosomal RNA.
Blood , Sept. 2007: 1458-65
Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated.
The Journal of clinical investigation , May 2007: 1440-9
Shwachman-Diamond syndrome.
Seminars in hematology , July 2006: 178-88
Inherited bone marrow failure syndromes: molecular features.
Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program , 2006: 63-71
The Shwachman-Diamond SBDS protein localizes to the nucleolus.
Blood , Aug. 2005: 1253-8
Detection of somatic mosaicism and classification of Fanconi anemia patients by analysis of the FA/BRCA pathway.
Blood , Feb. 2005: 1329-36
Association of biallelic BRCA2/FANCD1 mutations with spontaneous chromosomal instability and solid tumors of childhood.
Blood , April 2004: 2554-9
Acquired and Inherited Aplastic Anemia Syndromes
In: Greer, J.P., Foerster, J., Lukens, J.N., Rodgers, G.M., Paraskevas, F., Glader, B.E. Eds. Wintrobe's Clinical Hematology. 11th ed. Philadelphia: Lippincott Williams and Wilkins , 2004: 1397-1420
Acquired Aplastic Anemia
In: Nathan, D. G., Orkin, S. H., Look, A. T., and Ginsburg, D., editors. Nathan and Oski's Hematology on Infancy and Childhood, 6th Edition; Philadelphia: W.B Saunders and Co., , 2003: 256-279
Acquired Bone Marrow Failure Syndromes
In: Handin, R.I., Lux, S.E., Stossel, T.P., eds. Blood: Principles and Practice of Hematology, 2nd ed. Philadelpha: Lippincott Williams & Wilkins , 2003: 273-318
"Treatment of Hematological Disorders" in Fanconi Anemia: Standards for Clinical Care
Fanconi Anemia Research Fund , 2003: 17-36
Subtyping of Fanconi anemia patients: Implications for clincal management
Blood , 2003: 1023459-3459
A novel diagnostic screen for defects in the Fanconi anemia pathway.
Blood , Dec. 2002: 4649-54
Disruption of 3-Phosphoinositide-Dependent Kinase 1 (PKD1) Signaling by the anti-tumorigenic and anti-proliferative agent N-a-tosyl-L-phenylalanyl chloromethyl ketone
J. Biol.Chem. , 2001: 276(15)12466-12475
Structural Hemoglobinopathies
In: Scharschmidt, B. F. editor. Pocket Medicine/Internal Medicine, Philadelphia; PocketMedicine.com, Inc., , 2001 - 2006
RSK1 mediates a MEK/MAPK cell survival signal
Curr. Biol. , 2000: 10127-135
Distinct mathematical behavior of apoptotic versus non-apoptotic tumor cell death
Int. J. Radiat. Oncol. Biol. Phys. , 1999: 43(3)601-605
SMALL CELL SWEAT GLAND CARCINOMA IN CHILDHOOD
Am. J. Surg. Path. , 1998: 22(2)215-220
Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system
J. Biol. Chem. , 1998: 273(43)28378-28383
Low Molecular Weight Heparin
Hematology/Oncology Clinics of North America , 1998: 12(6)1251-1281
Transformation selective apoptosis in fibroblasts deprived of adhesion.
J. Cell Biol. , 1997: 138(4)901-011
Fanconi Anemia
In: /GeneReviews/ at GeneTests: Medical Genetics Information Resources [database online]. Copyright, University of Washington, Seattle. Available at www.genetests.org , 1997 - 2004
p53 in Life and Death.
Clinical Cancer Research. , 1996: 2435-440
Respiratory syncytial virus as a cause of fever and petechiae in infants.
Clinical Pediatrics , 1994: 32(6)355-356
Assembly and properties of chromatin containing histone H1.
J. Mol. Biol. , 1989: 209135-150
Assembly and properties of chromatin containing histone H1.
J. Mol. Biol. , 1989: 209135-150
Assembly of chromatin with oocyte extracts.
Methods Enzymol. , 1989: 170603-612
The assembly of regularly spaced nucleosomes in the Xenopus oocyte S-150 extract is accompanied by deacetylation of histone H4.
J. Biol. Chem. , 1989: 26414524-14530
Histone H1 represses transcription from minichromosomes assembled in vitro.
Mol. Cell. Biol. , 1989: 95573-5584
Assembly of chromatin with oocyte extracts
Methods Enzymol. , 1989: 170603-612
Characterization of the repressed 5S DNA minichromosomes assembled in vitro with a high-speed supernatant of Xenopus laevis oocytes.
Mol. Cell. Biol. , 1988: 84257-4269
Characterization of the repressed 5S DNA minchromosomes assembled in vitro with a high-speed supernatant of Xenopus laevis oocytes.
Mol. Cell. Biol. , 1988: 84257-4269
Hemoglobins with Altered Oxygen Affinity
In: Scharschmidt, B.F. editor. Pocket Medicine/Internal Medicine, Philadelphia; PocketMedicine.com, Inc., 2001, 2006. ,
Inherited Aplastic Anemia in Children
In: UpToDate, Rose B.D. (Ed), UpToDate, Waltham, MA ,
Guidelines for Diagnostic Work-Up and management of bone marrow failure patients (for Vampire Handbook, a clinical reference for Children's Hospital hematologists)
,
Cellular Basis of Hematopoiesis and Marrow Failure Syndromes. Chapter 2 In ASH-SAP Educational Book, 3rd Edition
,
Clinical Outcomes for Patients with Neutropenia Attributable to Mutations in the Gene for Neutrophil Elastase, ELANE
Clinical Outcomes for Patients with Severe Chronic Neutropenia International Registry (SCNIR) ,
Thalassemia
In: Scharschmidt, B.F. editor. Pocket Medicine/Internal Medicine, Philadelphia; PocketMedicine.com, Inc., 2001, 2006 ,

Presentations

Presentations TitleEventLocationDate
Invited SpeakerGrand RoundsBoston Children's Hospital, Boston, MA 2014
Invited SpeakerJackson LaboratoriesBar Harbor, ME 2013
Invited SpeakerScientific Congress on Shwachman-Diamond SyndromeUniversity of Toronto, ON, Canada 2013
Invited SpeakerGrand Rounds, Memorial Sloan Kettering Cancer CenterNew York, NY 2012
Ribosomal Disorders in Marrow FailureGrand Rounds, Ribosomal Disorders in Marrow FailureCincinnati Children's Hospital and Medical Center, Cincinnati, OH 2012
Invited Speaker9th International Conference on Ribosome SynthesisBanff, Alberta, Canada 2012
Fanconi AnemiaFanconi Anemia Family MeetingCamp Sunshine, ME 2011
Shwachman-Diamond SyndromeScientific Congress for Shwachman-Diamond SyndromeNew York 2011
Invited SpeakerRed Cell Gordon ConferenceNew Hampshire 2011
Invited Speaker23rd Annual Fanconi Anemia Research Fund Scientific SymposiumBarcelona, Spain 2011
Ribosomal disorders in marrow failure and malignancyAACR conference in Protein Translation and CancerSan Diego, CA 2010
Shwachman-Diamond SyndromeBMT Tandem MeetingOrlando, FL 2010
Masquerade! The inherited marrow failure syndromesGrand Rounds, Seattle Children's HospitalSeattle, WA 2010
Insights from inherited marrow failure syndromesGrand Rounds, Pediatric Hematology/OncologySt. Jude, Mephis, TN 2010
Insights from inherited marrow failure syndromes, Anne T. Bass Endowed LecturePediatric Hematology/OncologyStanford, Palo Alto, CA 2010
Shwachman Diamond SyndromeShwachman Diamond Syndrome Family MeetingCamp Sunshine, ME 2010
Presidential Symposium: Shwachman-Diamond SyndromeJapanese Society of Pediatric HematologyOsaka, Japan 2010
Non-Transplant Treatment of Aplastic Anemia, PNH, and Constitutional Marrow FailureAplastic Anemia and MDS International \Aplastic Anemia and MDS International Foundation 2010
Fanconi Anemia 101: An introduction to the science and medicine of Fanconi anemiaFanconi Anemia Research Fund Scientific SymposiumBaltimore, MD 2009
Shwachman-Diamond Syndrome and Translational researchAmerican Society of Pediatric Hematology/OncologySan Diego, CA 2009
Clinical Apporach to Marrow FailureAmerican Society of Hematology Education SessionNew Orleans, LA 2009
Treatment and Pathogenesis of Inherited Marrow Failure SyndromesJapanese Pediatric MDS/Aplastic Anemia meetingNagoya, Japan 2009
Shwachman-Diamond SyndromeInternational Society of Experimental HematologyAthens, Greece 2009
"FA 101"Fanconi Anemia Scientific ConferenceChicago, IL 2008
Diagnosis and Treatment of Bone Marow FailureConsensus Conference on Standards for Clnical Care of Fanconi Anemia Patients Chicago, IL 2008
The Decision to TransplantNational Neutropenia NetworkSeattle, WA 2008
Hematologic Issues In Shwachman-Diamond SyndromeShwachman-Diamond Syndrome Family MeetingCamp Sunshine, Casco, ME 2008
Fanconi anemia: Medical Management for Hematologic IssuesFanconi Anemia Family MeetingCamp Sunshine, Casco, ME 2008
Ribosomal Abnormalities in Shwachman-Diamond SyndromeNIDDK/NIH Workshop on Ribosomes and Their Role in DiseaseBethesda, MD 2008
AML in Fanconi Anemia Patients: Future DirectionsFanconi Anemia Research Fund Scientific SymposiumEugene, OR 2008
Fanconi Anemia 101: An introduction to the sciene and medicine of Fanconi anemiaFanconi Anemia research Fund Scientific SymposiumEugene, OR 2008
Severe Chronic NeturopeniaSevere Chronic Neturopenia family meetingSeattle, WA 2008
Fanconi AnemiaFanconi Anemia Family meetingCamp Sunshine, ME 2008
Shwachman-Diamond SyndromeShwachman-Diamond Syndrome family meetingCamp Sunshine, ME 2008
AML in Fanconi Anemia patients: Future DirectionsFanconi Anemia Research FundEugene, OR 2008
Fanconi Anemia 101: An introduction of the science and medicine of Fanconi anemiaFanconi Anemia Research Fund Scientific SymposiumEugene, OR 2008
Ribosomal Abnormalitities and Genomic Instability in Shwachman Diamond SyndromeJapanese Society of HematologyKyoto, Japan 2008
Myelodysplastic Syndromes and Bone Marrow FailureEuropean Society of Hematology Conference on Myelodysplastic Syndromes and Bone Marrow FailureAlbufeira, Portugal 2008
Invited speakerJapanese Society of HematologyKyoto, Japan 2008
Hematologic Abnormalities in Shwachman-Diamond Syndrome4th International Scientific Congress on Shwachman-Diamond Syndrome Boston, MA 2007
Ribosomal Dysfunction in Bone Marrow Failure SyndromesIn the Hot Topics in Paediatric and Adolescent Cancer and Blood Diseases ConferenceDublin, Ireland 2007
Shwachman-Diamond SyndromeGrand Rounds, Department of HematologyJohns Hopkins Hospital 2006
"FA 101"Fanconi Anemia Scientific ConferenceBethesda, MD 2006
Inherited Bone Marrow Failure SyndromesMarrow Failure Educational Session, American Society of HematologyOrlando, FL 2006
Shwachman-Diamond Syndromethe Myeloid Scientific Subcommittee Session, American Society of HematologyOrlando, FL 2006
Diagnostic Evaluation of Bone Marrow Failure in ChildrenAmerican Society of Pediatric Hematology/OncologyWashington, D.C. 2005
The SBDS Protein localizes to the nucleolusShwachman-Diamond Syndrome Scientific ConferenceCambridge, UK 2005
Intranuclear localization of the Shwachman-Diamond protein, SBDS: Functional ImplicationsAmerican Society of Pediatric Hematology/OncologySan Francisco, CA 2004
Monoubiquitined FANCD2 is both necessary and sufficient for mitomycin C resistance in the absence of a functional Fanconi Anemia core complexAmerican Society of HematologySan Diego, CA 2004
FA monoubiquitination and FA pathway functionFanconi Anemia Scientific ConferenceCambridge, MA 2004
The Fanconi Anemia DNA Repair Pathway Is Deficient in Acute Myeloid LeukemiaPediatric Academic Society MeetingSeatte. WA 2003
The Fanconi Anemia PathwayFanconi Anemia Family MeetingCamp Sunshine, Casco, ME 2003
Diagnosis and Treatment of Bone Marrow Failure Consensus Conference on Standards for Clinical Care of Fanconi Anemia PatientsChicago, IL 2003
Analysis of the human FANCD2 geneScientific Symposium, Fanconi Anemia Research FoundationHouston, TX 2003
Variable SBDS Protein Expression in Shwachman-Diamond Patients: Implications for PathogenesisAmerican Society of HematologySan Diego, CA 2003
Clinical applications of the FANCD2 monoubiquitination assayPediatric Academic Society meetingBaltimore, MD 2002
Fanconi AnemiaFanconi Anemia Cancer SymposiumChicago, IL 2002
The Fanconi anemia pathway: Clinical ImplicationsScientific Symposium, Fanconi Anemia Research FoundationPhiladelphia, PA 2002
A Screen for Acquired Fanconi Anemia Pathways Defects in Acute Myeloid LeukemiaAmerican Society of Hematology meetingPhiladelphia, PA 2002
Hematopoietic Stem Cell Biology and Plasticity RFA Hematopoietic Stem Cell Biology and Plasticity RFA MeetingNIH/NHLBI 2002
Clinical Approach to Bone Marrow Failure in ChildrenAmerican Society of Hematology Education Session on Marrow FailureAmerican Society of Hematology 2002
Signaling pathways regulating myeloid cell survivalSevere Congenital Neutropenia International RegistryOrlando, FL 2001
Fancomi AnemiaFanconi Anemia Family CampLake Geneva, WI 2001

Research Funding

Grant TitleGrantorAmountAward Date
R01 CA 181439-01 (Shimamura, Link)NIH / NCI $662,186 annual/3,342,968 total direct costsDec. 1, 2014 - Nov. 30, 2019
U54 TE6376 (Deeg)Medical College of Wisconsin / NIH $, $123,905 annual direct costsJuly 1, 2014 - June 30, 2019
R01 DK098479-01 (Shimamura)NIH/NIDDK $250,000 annual direct costsApril 1, 2014 - March 31, 2019
Department of Defense (Monnat)UW/Bone Marrow Failure Research Program Idea Development Award $, $, $7,500 annual direct costsMarch 1, 2014 - Feb. 28, 2017
Seattle Children's Hospital (Shimamura)Butterfly Guild $, $, $30,000 annual direct costsJan. 10, 2014 - Jan. 9, 2015
R24 DK099808-01 (Shimamura)National Institutes of Health $, $972,703 annual direct costsSept. 29, 2013 - Aug. 31, 2018
2013 Research Grant (Shimamura)Aplastic Anemia and MDS International Foundation $, $, $27, 273 annual direct costsJuly 1, 2013 - June 30, 2015
Seattle Children's Hospital (Shimamura)Aplastic Anemia Research Award $, $28,998 annual direct costsFeb. 1, 2013 - Jan. 31, 2014
Seattle Children's Hospital (Shimamura)Butterfly Guild $, $, $27,000 total direct costsAug. 1, 2012 - July 31, 2013
1R24 DK093425 (Abkowitz)UW/NIH/NIDDK $, $75,000 total direct costsMarch 1, 2012 - Aug. 31, 2013
1 R03 A1092423 (Torgerson)Seattle Children's Hospital/NIH/NIAID $, $, $9,136 annual/$17,966 total direct costsAug. 1, 2011 - July 31, 2013
St. Baldrick's Foundation (Shimamura) $, $100,000 total direct costsJuly 1, 2011 - June 30, 2012
Seattle Children's Hospital (Shimamura)Butterfly Guild $, $30,000 total direct costsJune 15, 2011 - June 14, 2012
R24 AI049393-10 (Dale)UW/National Institutes of Health $, $18,445 annual direct costsSept. 1, 2010 - Aug. 31, 2014
UL1 DE019582 (Scharenberg)Seattle Children's Hospital/NIH/NIDCR $, $73,575 annual / $122,625 total direct costsJuly 1, 2010 - June 30, 2012
5 RC1HL100270 (Shimamura, Torok-Storb)NIH/NHLBI $, $348,636 annual / $679,696 total direct costsSept. 30, 2009 - June 30, 2013
1 RC1 DK087680 (Thomas)University of Cincinnati/NIH/NIDDK $, $, $79,564 annual / $157,395 total direct costsSept. 30, 2009 - July 31, 2011
3 RO1 HL079582-06S1 (Shimamura) on Parent R01 Administrative SupplementNIH/NHLBI $, $190,174 total direct costsJuly 1, 2009 - June 3, 2011
Shwachman-Diamond America (Shimamura)Shwachman-Diamond Syndrome International Registry and Repository $, $10,000 total direct costsJan. 1, 2009 - Nov. 30, 2014
5 P30 DK056465 (Shimamura)CCEH (NIDDK) $, $20,000 total direct costsDec. 1, 2008 - Nov. 30, 2009
1 R03 AI079734 (Shimamura)NIH/NIAID $, $50,000 annual / $100,000 total direct costsSept. 17, 2008 - Aug. 31, 2011
Shwachman-Diamond Syndrome Project, LtdShwachman-Diamond Syndrome International Registry and Repository $, $89,000 total direct costsJuly 1, 2008 - June 30, 2012
R13 HL088725-01 (Grand)NIH / NHLBI $, $April 20, 2007 - March 31, 2008
200-2006-15969CDCJune 1, 2006 - Sept. 30, 2007
R01 HL079582-11 (Shimamura)National Institutes of Health $, $250,000 annual direct costsSept. 30, 2004 - May 31, 2014
5R01 HL079582-11 (Shimamura)National Institutes of Health $250,000 annual direct costsSept. 30, 2004 - May 31, 2014
5 K23 HL68632 (Shimamura)NIH / NHLBI $, $120,775 annual / $603,875 totalJuly 5, 2002 - May 31, 2008
Private Donor (Shimamura) 2002 - 2007
Scholars in Medicine (Shimamura) 2001
Hood Foundation (Shimamura) 2001
5 P50 HL54785 (Nathan)NIH / NHLBISept. 1, 2000 - Aug. 31, 2005
V Foundation (Shimamura) 1997
Howard Hughes (Shimamura) 1997

Primary Office

Fred Hutchinson Cancer Research Center
FHCRC Box 358080 - MS D2-100
PO Box 19024
Seattle, WA 98109-1024
206-667-6840

Additional Offices

Seattle Children's
MB.8.501 - Hematology-Oncology
4800 Sand Point Way NE
Seattle, WA 98105
206-987-2106

Find a Doctor or Researcher

Find a Doctor or Researcher

Type the first or last name you are searching for or select a specialty.

Doctor or Researcher Name:

More search options