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William R.A. Osborne, PhD

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William R.A. Osborne, PhD

Pediatrics-Inpatient

Academic Title: Research Professor, University of Washington

Research Center: Center for Genetics and Development

Overview

Awards and Honors

Award NameAward DescriptionAwarded ByAward Date
Henry Christian Memorial Award for Excellence in Clinical ResearchAmerican Federation of Clinical Research 1992

Publications

BB rat Gimap gene expression in sorted lymphoid T and B cells.
Life sciences , 2011 Nov 7: 89(19-20)748-54
Sustained glucagon-like peptide 1 expression from encapsulated transduced cells to treat obese diabetic rats.
Journal of bioscience and bioengineering , 2011 Apr: 111(4)383-7
Prolonged survival and improved glycemia in BioBreeding diabetic rats after early sustained exposure to glucagon-like peptide 1.
The journal of gene medicine , 2010 Jun: 12(6)538-44
Differential effects of leptin receptor mutation on male and female BBDR Gimap5-/Gimap5- spontaneously diabetic rats.
Physiological genomics , 2010 Mar 3: 41(1)9-20
Treatment of diabetic rats with encapsulated islets.
Journal of cellular and molecular medicine , 2008 Dec: 12(6B)2644-50
Glucose-regulated insulin production from genetically engineered human non-beta cells.
Life sciences , 2007 Oct 13: 81(17-18)1346-54
G-CSF-lentivirus administration in rats provided sustained elevated neutrophil counts and subsequent EPO-lentivirus administration increased hematocrits.
The journal of gene medicine , 2007 Jul: 9(7)571-8
An adult dog with cyclic neutropenia treated by lentivirus- mediated delivery of granulocyte colony-stimulating factor.
Human gene therapy , 2006 Apr: 17(4)464-9
Identification of functional single nucleotide polymorphism haplotypes in the cytidine deaminase promoter.
Human genetics , 2006 Apr: 119(3)276-83
Sustained elevation of neutrophils in rats induced by lentivirus-mediated G-CSF delivery.
The journal of gene medicine , 2005 Dec: 7(12)1510-6
Long-term erythropoietin gene expression from transduced cells in bioisolator devices.
Human gene therapy , 2003 Nov 20: 14(17)1587-93
Treatment of canine cyclic neutropenia by lentivirus-mediated G-CSF delivery.
Blood , 2003 Sep 15: 102(6)2046-52
Cloning and sequencing of the canine neutrophil elastase cDNA.
DNA sequence : the journal of DNA sequencing and mapping , 2002 Aug: 13(4)221-3
Modified blasticidin S resistance gene (bsrm) as a selectable marker for construction of retroviral vectors.
Journal of biotechnology , 2002 Apr 25: 95(1)57-62

Research Funding

Grant TitleGrantorAmountAward Date
Effect of Nutritional Factors on Macrophage Accumulation in Adipose TissueNIH/NHLBI July 1, 2009 - June 30, 2014

Additional Offices

Seattle Children's
OC.9.850 - Medical Genetics
4800 Sand Point Way NE
Seattle, WA 98105
206-987-2056

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