Stephen W. Standage, MD

Stephen W. Standage, MD

Critical Care, PICU

On staff since July 2011

Academic Title: Acting Assistant Professor

Language (Other than English): Spanish

"Severe illness or injury is a devastating, often unanticipated event in the life of a child and their family. The tenacity, strength, resilience, and love demonstrated by the children, their family members, and care providers during these difficult times truly inspire me. I am driven each day, in both my clinical and research efforts, by a desire to improve the outcome for each child."

  • Stephen Standage, MD, is attending physician at Seattle Children’s Hospital and Harborview Medical Center and acting assistant professor of pediatrics at the University of Washington School of Medicine. He earned his MD at the University of Rochester, in Rochester, New York, and completed his pediatrics residency at The Children’s Hospital of Philadelphia. Dr. Standage completed his pediatric critical care fellowship training at Cincinnati Children’s Hospital.

    Dr. Standage is a member of the University of Washington Center for Lung Biology and conducts his research at their South Lake Union facility. His laboratory work is directed at understanding the molecular mechanisms of the immune response in sepsis. Specifically, he is interested in how modulation of systemic inflammation can improve patient outcome in critical illness. Dr. Standage’s current investigations focus on macrophage biology and the nuclear hormone receptor PPAR alpha. He is a member of the American Academy of Pediatrics, the Society of Critical Care Medicine, the Shock Society, and the American Heart Association.

    • Julia Kingston, WA 12.07.14

      Dr. Standage, one of the greatest doctors at Seattle Children's Hospital. Ive been under his care multiple times when I was admitted to the hospital last summer. He was so determined to figure out what was wrong with me. When I had my shunt externalized, for sure he was watching my ICP numbers spike every time I had an episode. I had a couple surgeries done hoping to give my brain space to settle down. To this day I had numerous surgeries performed, but there is still no explanation to why my brain was doing whatever it was doing. In conclusion I would like to thank Dr. Standage for everything he has done for me. Your the greatest Dr. Steve!!!! Julia Bryant

    • Basu RK, Standage SW, Cvijanovich NZ, Allen GL, Thomas NJ, Freishtat RJ, Anas N, Meyer K, Checchia PA, Lin R, Shanley TP, Bigham MT, Wheeler DS, Devarajan P, Goldstein SL, Wong HR
      Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray.
      22098946 Critical care (London, England) , 2011 Nov. 18 : R273
    • Standage SW, Caldwell CC, Zingarelli B, Wong HR
      Reduced PPARa Expression is Associated With Decreased Survival and Increased Tissue Bacterial Load in Sepsis.
      22089192 Shock (Augusta, Ga.) , 2011 Nov. 15
    • Kilpatrick LE, Standage SW, Li H, Raj NR, Korchak HM, Wolfson MR, Deutschman CS
      Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-d (d-PKC).
      20724665 Journal of leukocyte biology , 2011 Jan. : 3-10
    • Standage SW, Wong HR
      Biomarkers for pediatric sepsis and septic shock.
      21171879 Expert review of anti-infective therapy , 2011 Jan. : 71-9
    • Maffei FA, van der Jagt EW, Powers KS, Standage SW, Connolly HV, Harmon WG, Sullivan JS, Rubenstein JS
      Duration of mechanical ventilation in life-threatening pediatric asthma: description of an acute asphyxial subgroup.
      15342851 Pediatrics , 2004 Sept. : 762-7


Board Certification(s)

Pediatric Critical Care Medicine

Medical/Professional School

University of Rochester School of Medicine and Dentistry, Rochester


Pediatrics, Children's Hospital of Philadelphia, Philadelphia


Pediatric Critical Care Medicine, Cincinnati Children's Hospital, Cincinnati

Clinical Interests

Sepsis, systemic inflammatory response syndromes (SIRS), hemophagocytic lymphohistiocytosis (HLH), shock, and acute respiratory failure.

Research Description

I investigate the basic mechanisms of immune dysregulation in the body's response to severe infectious or inflammatory challenge with the goal to identify therapeutic interventions.