Ryan M. McAdams, MD

Ryan M. McAdams, MD


On staff since October 2008

Academic Title: Associate Professor of Pediatrics

Research Center: Center for Clinical and Translational Research

"As a parent, I treasure how precious, unique, and vulnerable a baby is, especially when they are born with complicated medical issues. I am a neonatologist who always strives to respectfully care for every baby in the neonatal intensive care unit in a manner that promotes optimal healing, safe medical practices, open family communication, and a devotion to their best interests. I am hopeful that through our research efforts we will help improve neurodevelopmental outcomes in vulnerable infants and give them a chance to achieve their highest potential."

  • Dr. McAdams is a neonatologist with clinical experience in both developed and developing countries. He has been involved in volunteer medical humanitarianism work in developing countries including Mongolia, Zambia, Cambodia, and Uganda with a goal to improve neonatal outcomes globally. The inspiration for his scientific research derives from his clinical exposure to vulnerable newborns who have sustained lung and brain injuries.

    Dr. McAdams research focuses on understanding early epigenetic mechanisms that may alter long-term lung and brain development. He is studying how in utero inflammatory signaling pathways affect gene expression in the developing lung in order to identify potential therapeutic windows to mitigate fetal and neonatal lung injury. Additionally, Dr. McAdams is investigating how pain and sedation medications commonly used in the NICU can alter levels of microRNAs, small non-coding RNA molecules that can regulate gene expression, in the neonatal brain. The goal of this work is to determine the potential neurodevelopmental impact of pain and sedation medicines to make sure these medicines are used in a safe and judicious manner in neonates. Dr. McAdams is also a strong advocate of improving care practices through the implementation of evidence-based practices with a current interest in advocating for delayed cord clamping in newborns to optimize neurodevelopmental outcomes.

    • Jericho monroe, washington 03.21.13

      Thank God for Ryan McAdams he is an amazing person. Our daughter was in the NICU and Dr.McAdams was the only doctor that would talk to my husband and I like real people he never once made us feel like we were being treated like stupid parents who know nothing (like most doctors these days). He always was there for us and when he had to break us bad news he did it himself he even came back to the hospital after he was off work to sit with us when our daughter wasn't doing well. He made sure we understood all of our options and helped us with the research. After our daughter passed he even went to see her twin brother in UW NICU before our son was able to come home just so he could make sure that our son was healthy. Thank you doctor McAdams, we will be seeing you soon with our next baby and we are so happy that you will be part of the team that helps our son. Thank you again.

    • Lawrence Renton, WA 09.30.12

      Dr McAdams is more than just a wonderful doctor he is a wonderful man. He always had time for my wife and I while our son was in the Nicu. He spoke to us like human beings when we had questions. He never once spoke down to us. Our only regret is that he does not have an outside pediatrician practice as he would surely be our sons primary care doctor. Thank you so much Dr McAdams.

    • Melissa Richland, Washington 12.20.11

      I thank God for Dr. McAdams! He is a wonderful Doctor that had to make some tough decisions with our son's care. He looked outside the box and as a result, we believe he played a big role in saving our son's life. He took a lot of time to come and talk with us whenever we had concerns. I especially appreciate him talking to us intelligently rather than talking down to us. He helped us learn a lot about our son's condition. Thank you Dr. McAdams! Augustus' Mom and Dad

  • Award Name Award Description Awarded By Award Date
    Seattles Top Doctor 2016 Seattle Met Magazine 2016
    SEATTLE MAGAZINE TOP DOCTOR - 2015 Seattle Magazine 2015
    SEATTLE'S TOP DOCTOR - 2014 Seattle Metropolitan Magazine 2014
    Seattle's Top Doc Seattle Met Magazine 2013
    Finalist: digital photograph "Waiting at the Crossroads." Seattle Childrens Hospital Research Staff Development Committee Research Symposium, Lab art display, Seattle, WA 2011
    Finalist: digital photograph "Hypertrophy on Glass." Seattle Childrens Hospital Research Staff Development Committee "Lab Art: Stepping off the Carpet" Research Symposium, Seattle, WA 2010
    Outstanding Teacher of the Year This award is selected by the residents of the University of Washington Pediatric Residency Program 2009 - 2010
    Teacher of the Year This award is selected by Japanese Intern Class, US Naval Hospital, Okinawa, Japan 2006 - 2007
    • McAdams RM, McPherson RJ, Batra M, Gerelmaa Z
      Characterization of health care provider attitudes toward parental involvement in neonatal resuscitation-related decision making in mongolia.
      23807716 Maternal and child health journal , 2014 May : 18(4)920-9
    • McAdams RM
      Time to implement delayed cord clamping.
      24499758 Obstetrics and gynecology , 2014 Mar. : 123(3)549-52
    • Vanderhoeven JP, Bierle CJ, Kapur RP, McAdams RM, Beyer RP, Bammler TK, Farin FM, Bansal A, Spencer M, Deng M, Gravett MG, Rubens CE, Rajagopal L, Adams Waldorf KM
      Group B streptococcal infection of the choriodecidua induces dysfunction of the cytokeratin network in amniotic epithelium: a pathway to membrane weakening.
      24603861 PLoS pathogens , 2014 Mar. : 10(3)e1003920 PMCID: PMC3946355
    • McAdams RM
      Artist's statement: Wait and See.
      24473571 Academic medicine : journal of the Association of American Medical Colleges , 2014 Feb. : 89(2)263
    • McAdams RM
      Coping on canvas.
      24026783 JAMA pediatrics , 2013 Sept. : 167(9)795
    • Soileau SL, Schneider E, Erdman DD, Lu X, Ryan WD, McAdams RM
      Case report: severe disseminated adenovirus infection in a neonate following water birth delivery.
      23417617 Journal of medical virology , 2013 Apr, : 85(4)667-9
    • Traudt CM, McPherson RJ, Bauer LA, Richards TL, Burbacher TM, McAdams RM, Juul SE
      Concurrent erythropoietin and hypothermia treatment improve outcomes in a term nonhuman primate model of perinatal asphyxia.
      24192275 Developmental neuroscience , 2013 : 35(6)491-503 PMCID: PMC3873854
    • Tanya Chun P, Chun T, Files M, Vo N, McAdams RM
      Percutaneous embolization of congenital portosystemic venous fistula in an infant with down syndrome.
      24171135 Case reports in vascular medicine , 2013 : 2013127023 PMCID: PMC3792513
    • Adams Waldorf KM, McAdams RM
      Influence of infection during pregnancy on fetal development.
      23884862 Reproduction (Cambridge, England) , 2013 : 146(5)R151-62
    • McAdams RM
      Artist's statement: Champei's Petals.
      23010975 Academic medicine : journal of the Association of American Medical Colleges , 2012 Oct. : 87(10)1367
    • McAdams RM, Erdenebileg A, Batra M, Gerelmaa Z
      Attitudes of healthcare providers towards non-initiation and withdrawal of neonatal resuscitation for preterm infants in Mongolia.
      23082636 Journal of health, population, and nutrition , 2012 Sept. : 30(3)346-52 PMCID: PMC3489950
    • Namiiro FB, Mugalu J, McAdams RM, Ndeezi G
      Poor birth weight recovery among low birth weight/preterm infants following hospital discharge in Kampala, Uganda.
      22230245 BMC pregnancy and childbirth , 2012 Jan. 9 : 121 PMCID: PMC3282660
    • McAdams RM, Vanderhoeven J, Beyer RP, Bammler TK, Farin FM, Liggitt HD, Kapur RP, Gravett MG, Rubens CE, Adams Waldorf KM
      Choriodecidual infection downregulates angiogenesis and morphogenesis pathways in fetal lungs from Macaca nemestrina.
      23056493 PloS one , 2012 : 7(10)e46863 PMCID: PMC3467273
    • McAdams RM, Juul SE
      The role of cytokines and inflammatory cells in perinatal brain injury.
      22530124 Neurology research international , 2012 : 2012561494 PMCID: PMC3317045

  • Grant Title Grantor Amount Award Date
    "Is prolonged exposure to dexmedetomidine safe for neonates?" Seattle Children's Hospital Center for Clinical and Translational Research Grant, Seattle, WA $20000 Sept. 28, 2012 - Sept. 28, 2013
    "GBS mediated in utero fetal injury" NIH $620,956 July 1, 2012 - June 30, 2017
    "GBS mediated in utero fetal injury" NIH $620,956 July 1, 2012 - June 30, 2017
    "Are the neurodevelopmental effects of neonatal stress and morphine regulated by miRNAs?" $25,000
    Optimizing neuroprotection following perinatal asphyxia" NIH/NICHD $2,196,613 Sept. 17, 2007 - June 30, 2012


Medical/Professional School

Medical College of Wisconsin, Milwaukee


Pediatrics, David Grant Medical Center, Travis AFB


Neonatal-Perinatal Medicine, Wilford Hall Medical Center, Lackland AFB

Clinical Interests

Clinical focus: Promoting quality improvement in medical education; utilizing evidence-based teamwork systems to optimize patient outcomes; improving neonatal medical transports Research focus: Short and long-term effects of neonatal vascular injury and development; infection-associated preterm birth; improving global newborn care in resource-poor settings