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Raj P. Kapur, MD, PhD

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Raj P. Kapur, MD, PhD

Pathology, Reconstructive Pelvic Medicine

On staff since November 1992

Children's Title: Program Chief, Perinatal Autopsy; Program Director, Fetal Pathology Service; Program Director of Lab Medicine/Pathology Residency and Fellowship

Academic Title: Professor

Research Center: Center for Developmental Biology and Regenerative Medicine

Overview

Board Certification(s)
Pathology - Anatomic
Pediatric Pathology
Medical/Professional School
University of Southern California, Los Angeles
Residency
Pathology - Anatomic, University of Washington, Seattle
Fellowship
Pediatric Pathology, Seattle Children's Hospital, Seattle
Clinical Interests

Hirschsprung disease and related disorders, Fetal pathology

Research Focus Area

Translational Research

Publications

Diffuse abnormal layering of small intestinal smooth muscle is present in patients with FLNA mutations and x-linked intestinal pseudo-obstruction.
The American journal of surgical pathology , 2010 Oct: 1528-43
Neuronal migration disorders in microcephalic osteodysplastic primordial dwarfism type I/III.
Acta neuropathologica , 2010 Sep 21
Counting myenteric ganglion cells in histologic sections: an empirical approach.
Human pathology , 2010 Aug: 1097-108
The London Classification of gastrointestinal neuromuscular pathology: report on behalf of the Gastro 2009 International Working Group.
Gut , 2010 Jul: 882-7
Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome.
Proceedings of the National Academy of Sciences of the United States of America , 2010 Jun 15: 10996-1001
Fetal akinesia deformation sequence with delayed skeletal muscle maturation and polymicrogyria: evidence for a hypoxic/ischemic pathogenesis.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2010 May-Jun: 192-201
PHOX2B Immunolocalization of the Candidate Human Retrotrapezoid Nucleus.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2009 Nov 4
Practical pathology and genetics of Hirschsprung's disease.
Seminars in pediatric surgery , 2009 Nov: 212-23
Normal and abnormal anatomy of the cerebellar vermis in midgestational human fetuses.
Birth defects research. Part A, Clinical and molecular teratology , 2009 Aug: 700-9
Gastrointestinal neuromuscular pathology: guidelines for histological techniques and reporting on behalf of the Gastro 2009 International Working Group.
Acta neuropathologica , 2009 Aug: 271-301
Collagenous gastritis, a new spectrum of disease in pediatric patients: two case reports.
Cases journal , 2009 Jun 10: 7511
Architectural malformation of the muscularis propria as a cause for intestinal pseudo-obstruction: two cases and a review of the literature.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2009 Mar-Apr: 156-64
Calretinin immunohistochemistry versus acetylcholinesterase histochemistry in the evaluation of suction rectal biopsies for Hirschsprung Disease.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2009 Jan-Feb: 6-15
Retinal function and corresponding pathology in advanced retinoblastoma.
Archives of ophthalmology , 2008 Nov: 1507-12
Androgenetic/biparental mosaicism in an infant with hepatic mesenchymal hamartoma and placental mesenchymal dysplasia.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2008 Sep-Oct: 377-83
Hepatic mesenchymal hamartoma: a disorder of imprinting.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2008 Jul-Aug: 264-5
Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy.
Cell metabolism , 2008 Apr: 312-20
Characterization of developing bowel transplanted from transgenic erythropoietin receptor-deficient mouse embryos.
Neonatology , 2008: 56-63
Five cases of caudal regression with an aberrant abdominal umbilical artery: Further support for a caudal regression-sirenomelia spectrum.
American journal of medical genetics. Part A , 2007 Dec 15: 3175-84
Visceral neuropathy and intestinal pseudo-obstruction in a murine model of a nuclear inclusion disease.
Gastroenterology , 2007 Dec: 1971-8
Achondrogenesis.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2007 Jul-Aug: 253-5
A case of true hermaphroditism reveals an unusual mechanism of twinning.
Human genetics , 2007 Apr: 179-85
Genetic disruption of dopamine production results in pituitary adenomas and severe prolactinemia.
Neuroendocrinology , 2007: 48-57
Intestinal neuronal dysplasia type B: one giant ganglion is not good enough.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2006 Nov-Dec: 444-52
Does bcl2 immunostaining really help with pathological evaluation of intestinal pseudo-obstruction?
The American journal of surgical pathology , 2006 Aug: 1059; author reply 1059-62
Can we stop looking? Immunohistochemistry and the diagnosis of Hirschsprung disease.
American journal of clinical pathology , 2006 Jul: 9-12
Dandy-Walker malformation complex: correlation between ultrasonographic diagnosis and postmortem neuropathology.
Obstetrics and gynecology , 2006 Mar: 685-93
Inhibition of protein kinase A in murine enteric neurons causes lethal intestinal pseudo-obstruction.
Journal of neurobiology , 2006 Feb 15: 256-72
Evaluation of Hox11L1 in the fmc/fmc rat model of chronic intestinal pseudo-obstruction.
Journal of pediatric surgery , 2005 Nov: 1760-5
Association of cloacal anomalies, caudal duplication, and twinning.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2005 May-Jun: 339-54
Multiple endocrine neoplasia type 2B and Hirschsprung's disease.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association , 2005 May: 423-31
Holoprosencephaly and limb reduction defects: a consideration of Steinfeld syndrome and related conditions.
American journal of medical genetics. Part A , 2005 May 1: 381-92
Hox11L1 expression by precursors of enteric smooth muscle: an alternative explanation for megacecum in HOX11L1-/- mice.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2005 Mar-Apr: 148-61
Both CD1d antigen presentation and interleukin-12 are required to activate natural killer T cells during Trypanosoma cruzi infection.
Infection and immunity , 2005 Mar: 1890-4
Methods for induced abortion.
Obstetrics and gynecology , 2005 Jan: 221; author reply 221-2
Critical proinflammatory and anti-inflammatory functions of different subsets of CD1d-restricted natural killer T cells during Trypanosoma cruzi infection.
Infection and immunity , 2005 Jan: 181-92
Malignant autosomal recessive osteopetrosis caused by spontaneous mutation of murine Rank.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research , 2004 Oct: 1689-97
Pathologic quiz case: a 10-year-old boy with weakness, lethargy, and edema. Arrhythmogenic right ventricular cardiomyopathy, cardiomyopathic pattern.
Archives of pathology & laboratory medicine , 2004 Jun: 700-2
Immunohistologic evidence supports apoptosis, IgG deposition, and novel macrophage/fibroblast crosstalk in the pathologic cascade leading to congenital heart block.
Arthritis and rheumatism , 2004 Jan: 173-82
Quercetin, an over-the-counter supplement, causes neuroblastoma-like elevation of plasma homovanillic acid.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2003 Nov-Dec: 547-51
Genetic background modifies intestinal pseudo-obstruction and the expression of a reporter gene in Hox11L1-/- mice.
Gastroenterology , 2003 Nov: 1428-40
Neuronal dysplasia: a controversial pathological correlate of intestinal pseudo-obstruction.
American journal of medical genetics. Part A , 2003 Nov 1: 287-93
Cytokine polymorphisms and histologic expression in autopsy studies: contribution of TNF-alpha and TGF-beta 1 to the pathogenesis of autoimmune-associated congenital heart block.
Journal of immunology (Baltimore, Md. : 1950) , 2003 Sep 15: 3253-61
A report of dizygous monochorionic twins.
The New England journal of medicine , 2003 Jul 10: 154-8
A little bit of everything: molecular genetics of congenital hyperinsulinism.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2003 Jan-Feb: 3-5
Rulers rule: present and future applications of cerebellar morphometry.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society , 2002 Sep-Oct: 422-4
Transdifferentiation of cardiac fibroblasts, a fetal factor in anti-SSA/Ro-SSB/La antibody-mediated congenital heart block.
Journal of immunology (Baltimore, Md. : 1950) , 2002 Aug 15: 2156-63
Hydrocephalus and intestinal aganglionosis: is L1CAM a modifier gene in Hirschsprung disease?
American journal of medical genetics , 2002 Feb 15: 51-6

Primary Office

Seattle Children's
OC.8.720 - Pathology Lab
4800 Sand Point Way NE
Seattle, WA 98105
206-987-2103

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