Profile

Michele Shaffer, PhD

Michele Shaffer, PhD

Gastroenterology and Hepatology Research

Children's Title: Co-Director, Seattle Children's Core for Biomedical Statistics

Academic Title: Associate Professor of Pediatrics, Division of Gastroenterology

Research Center: Center for Clinical and Translational Research

Overview

Medical/Professional School

Pennsylvania State University, University Park
Pennsylvania State University, University Park
Pennsylvania State University, University Park

Awards and Honors

Award Name Award Description Awarded By Award Date
Deans Award for Excellence in Teaching Penn State College of Medicine 2011

Publications

  • Suskind DL, Brittnacher MJ, Wahbeh G, Shaffer ML, Hayden HS, Qin X, Singh N, Damman CJ, Hager KR, Nielson H, Miller SI
    Fecal microbial transplant effect on clinical outcomes and fecal microbiome in active Crohn's disease.
    25647155 Inflammatory bowel diseases , 2015 Mar. : 21(3)556-63 PMCID: PMC4329080
  • Suskind DL, Brittnacher MJ, Wahbeh G, Shaffer ML, Hayden HS, Qin X, Singh N, Damman CJ, Hager KR, Nielson H, Miller SI
    Fecal microbial transplant effect on clinical outcomes and fecal microbiome in active Crohn's disease.
    25647155 Inflammatory bowel diseases , 2015 Mar. : 21(3)556-63 PMCID: PMC4329080
  • Fernandez-Mendoza J, Shaffer ML, Olavarrieta-Bernardino S, Vgontzas AN, Calhoun SL, Bixler EO, Vela-Bueno A
    Cognitive-emotional hyperarousal in the offspring of parents vulnerable to insomnia: a nuclear family study.
    24889269 Journal of sleep research , 2014 Oct. : 23(5)489-98
  • Mitchell SL, Shaffer ML, Loeb MB, Givens JL, Habtemariam D, Kiely DK, D'Agata E
    Infection management and multidrug-resistant organisms in nursing home residents with advanced dementia.
    25133863 JAMA internal medicine , 2014 Oct. : 174(10)1660-7 PMCID: PMC4188742
  • Lee EY, Sen S, Eslinger PJ, Wagner D, Shaffer ML, Kong L, Lewis MM, Du G, Huang X
    Early cortical gray matter loss and cognitive correlates in non-demented Parkinson's patients.
    23932064 Parkinsonism & related disorders , 2013 Dec. : 19(12)1088-93 PMCID: PMC3858507
  • Lee EY, Sen S, Eslinger PJ, Wagner D, Shaffer ML, Kong L, Lewis MM, Du G, Huang X
    Early cortical gray matter loss and cognitive correlates in non-demented Parkinson's patients.
    23932064 Parkinsonism & related disorders , 2013 Dec. : 19(12)1088-93 PMCID: PMC3858507
  • DeSorbo AL, Noble JM, Shaffer M, Gerin W, Williams OA
    The use of an audience response system in an elementary school-based health education program.
    23086554 Health education & behavior : the official publication of the Society for Public Health Education , 2013 Oct. : 40(5)531-5
  • Dolbier CL, Rush TE, Sahadeo LS, Shaffer ML, Thorp J, Community Child Health Network Investigators
    Relationships of race and socioeconomic status to postpartum depressive symptoms in rural African American and non-Hispanic white women.
    22961387 Maternal and child health journal , 2013 Sept. : 17(7)1277-87 PMCID: PMC3584227
  • Lloyd T, Shaffer ML, Christy S, Widome MD, Repke J, Weitekamp MR, Eslinger PJ, Bargainnier SS, Paul IM
    Health knowledge among the millennial generation.
    25170479 Journal of public health research , 2013 Apr, 28 : 2(1)38-41 PMCID: PMC4140324
  • Mitchell SL, Shaffer ML, Kiely DK, Givens JL, D'Agata E
    The study of pathogen resistance and antimicrobial use in dementia: study design and methodology.
    22925431 Archives of gerontology and geriatrics , 2013 Jan. : 56(1)16-22 PMCID: PMC3502703
  • Du G, Lewis MM, Sen S, Wang J, Shaffer ML, Styner M, Yang QX, Huang X
    Imaging nigral pathology and clinical progression in Parkinson's disease.
    23008179 Movement disorders : official journal of the Movement Disorder Society , 2012 Nov. : 27(13)1636-43 PMCID: PMC3510346
  • Fernandez-Mendoza J, Vgontzas AN, Liao D, Shaffer ML, Vela-Bueno A, Basta M, Bixler EO
    Insomnia with objective short sleep duration and incident hypertension: the Penn State Cohort.
    22892811 Hypertension , 2012 Oct. : 60(4)929-35 PMCID: PMC3679545
  • Ofoma U, He F, Shaffer ML, Naccarelli GV, Liao D
    Premature cardiac contractions and risk of incident ischemic stroke.
    23316293 Journal of the American Heart Association , 2012 Oct. : 1(5)e002519 PMCID: PMC3541607
  • Geskey JM, Erdman HJ, Bramley HP, Williams RJ, Shaffer ML
    Superior mesenteric artery syndrome in intellectually disabled children.
    22453730 Pediatric emergency care , 2012 Apr, : 28(4)351-3
  • Wang J, Shaffer ML, Eslinger PJ, Sun X, Weitekamp CW, Patel MM, Dossick D, Gill DJ, Connor JR, Yang QX
    Maturational and aging effects on human brain apparent transverse relaxation.
    22363767 PloS one , 2012 : 7(2)e31907 PMCID: PMC3283700
  • Du G, Lewis MM, Shaffer ML, Chen H, Yang QX, Mailman RB, Huang X
    Serum cholesterol and nigrostriatal R2* values in Parkinson's disease.
    22530017 PloS one , 2012 : 7(4)e35397 PMCID: PMC3328461
  • Du G, Lewis MM, Styner M, Shaffer ML, Sen S, Yang QX, Huang X
    Combined R2* and diffusion tensor imaging changes in the substantia nigra in Parkinson's disease.
    21618607 Movement disorders : official journal of the Movement Disorder Society , 2011 Aug. 1 : 26(9)1627-32 PMCID: PMC3154471
  • Li X, Shaffer ML, Rodríguez-Colón SM, He F, Bixler EO, Vgontzas AN, Wolbrette DL, Wu C, Ball RW, Liao D
    Systemic inflammation and circadian rhythm of cardiac autonomic modulation.
    21444250 Autonomic neuroscience : basic & clinical , 2011 July 5 : 162(1-2)72-6 PMCID: PMC3111893
  • He F, Shaffer ML, Rodriguez-Colon S, Yanosky JD, Bixler E, Cascio WE, Liao D
    Acute effects of fine particulate air pollution on cardiac arrhythmia: the APACR study.
    21398201 Environmental health perspectives , 2011 July : 119(7)927-32 PMCID: PMC3222979
  • Dias MS, Shaffer ML, Iantosca MR, Hill KL Jr
    Variability among pediatric neurosurgeons in the threshold for ventricular shunting in asymptomatic children with hydrocephalus.
    21284457 Journal of neurosurgery. Pediatrics , 2011 Feb. : 7(2)134-42
  • Dias MS, Shaffer ML, Iantosca MR, Hill KL Jr
    Variability among pediatric neurosurgeons in the threshold for ventricular shunting in asymptomatic children with hydrocephalus.
    21284457 Journal of neurosurgery. Pediatrics , 2011 Feb. : 7(2)134-42
  • Kiely DK, Givens JL, Shaffer ML, Teno JM, Mitchell SL
    Hospice use and outcomes in nursing home residents with advanced dementia.
    21143437 Journal of the American Geriatrics Society , 2010 Dec. : 58(12)2284-91 PMCID: PMC3057929
  • He F, Shaffer ML, Rodriguez-Colon S, Bixler EO, Vgontzas AN, Williams RW, Wu R, Cascio WE, Liao D
    Acute effects of fine particulate air pollution on ST segment height: a longitudinal study.
    21059260 Environmental health : a global access science source , 2010 Nov. 8 : 968 PMCID: PMC2989950
  • Mitchell SL, Miller SC, Teno JM, Davis RB, Shaffer ML
    The advanced dementia prognostic tool: a risk score to estimate survival in nursing home residents with advanced dementia.
    20621437 Journal of pain and symptom management , 2010 Nov. : 40(5)639-51 PMCID: PMC2981683
  • Givens JL, Jones RN, Shaffer ML, Kiely DK, Mitchell SL
    Survival and comfort after treatment of pneumonia in advanced dementia.
    20625013 Archives of internal medicine , 2010 July 12 : 170(13)1102-7 PMCID: PMC2914628
  • Liao D, Shaffer ML, Rodriguez-Colon S, He F, Li X, Wolbrette DL, Yanosky J, Cascio WE
    Acute adverse effects of fine particulate air pollution on ventricular repolarization.
    20363686 Environmental health perspectives , 2010 July : 118(7)1010-5 PMCID: PMC2920900
  • Thomas NJ, Shaffer ML, Willson DF, Shih MC, Curley MA
    Defining acute lung disease in children with the oxygenation saturation index.
    19561556 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2010 Jan. : 11(1)12-7 PMCID: PMC2936504
  • Thomas NJ, Shaffer ML, Willson DF, Shih MC, Curley MA
    Defining acute lung disease in children with the oxygenation saturation index.
    19561556 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2010 Jan. : 11(1)12-7 PMCID: PMC2936504
  • Lowe J, MacLean PC, Shaffer ML, Watterberg K
    Early working memory in children born with extremely low birth weight: assessed by object permanence.
    19339284 Journal of child neurology , 2009 Apr, : 24(4)410-5 PMCID: PMC3071030
  • Shaffer ML, Kunselman AR, Watterberg KL
    Analysis of neonatal clinical trials with twin births.
    19245713 BMC medical research methodology , 2009 Feb. 26 : 912 PMCID: PMC2676314
  • Aucott SW, Watterberg KL, Shaffer ML, Donohue PK, PROPHET Study Group
    Do cortisol concentrations predict short-term outcomes in extremely low birth weight infants?
    18829801 Pediatrics , 2008 Oct. : 122(4)775-81 PMCID: PMC3586215
  • Tamburro RF, Barfield RC, Shaffer ML, Rajasekaran S, Woodard P, Morrison RR, Howard SC, Fiser RT, Schmidt JE, Sillos EM
    Changes in outcomes (1996-2004) for pediatric oncology and hematopoietic stem cell transplant patients requiring invasive mechanical ventilation.
    18446105 Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies , 2008 May : 9(3)270-7
  • Paul IM, Beiler J, McMonagle A, Shaffer ML, Duda L, Berlin CM Jr
    Effect of honey, dextromethorphan, and no treatment on nocturnal cough and sleep quality for coughing children and their parents.
    18056558 Archives of pediatrics & adolescent medicine , 2007 Dec. : 161(12)1140-6
  • Stultz EE, Stokes JL, Shaffer ML, Paul IM, Berlin CM
    Extent of medication use in breastfeeding women.
    17903100 Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine , 2007 Sept. : 2(3)145-51
  • Watterberg KL, Shaffer ML, Mishefske MJ, Leach CL, Mammel MC, Couser RJ, Abbasi S, Cole CH, Aucott SW, Thilo EH, Rozycki HJ, Lacy CB
    Growth and neurodevelopmental outcomes after early low-dose hydrocortisone treatment in extremely low birth weight infants.
    17606560 Pediatrics , 2007 July : 120(1)40-8
  • Paul IM, Wai K, Jewell SJ, Shaffer ML, Varadan VV
    Evaluation of a new self-contained, ambulatory, objective cough monitor.
    17005042 Cough (London, England) , 2006 Sept. 27 : 27 PMCID: PMC1592112
  • Yoder KE, Shaffer ML, La Tournous SJ, Paul IM
    Child assessment of dextromethorphan, diphenhydramine, and placebo for nocturnal cough due to upper respiratory infection.
    16928841 Clinical pediatrics , 2006 Sept. : 45(7)633-40
  • Vitale MA, Rzucidlo S, Shaffer ML, Ceneviva GD, Thomas NJ
    The impact of pediatric trauma in the Amish community.
    16615967 The Journal of pediatrics , 2006 Mar. : 148(3)359-65
  • Naeye RL, Shaffer ML
    Postnatal laboratory timers of antenatal hypoxemic-ischemic brain damage.
    16079907 Journal of perinatology : official journal of the California Perinatal Association , 2005 Oct. : 25(10)664-8
  • Liu W, Zhao W, Shaffer ML, Icitovic N, Chase GA
    Modelling clinical trials in heterogeneous samples.
    16007572 Statistics in medicine , 2005 Sept. 30 : 24(18)2765-75
  • Paul IM, Shaffer ML, Yoder KE, Sturgis SA, Baker MS, Berlin CM Jr
    Dose-response relationship with increasing doses of dextromethorphan for children with cough.
    15531013 Clinical therapeutics , 2004 Sept. : 26(9)1508-14
  • Liu W, Icitovic N, Shaffer ML, Chase GA
    The impact of population heterogeneity on risk estimation in genetic counseling.
    15228628 BMC medical genetics , 2004 June 30 : 518 PMCID: PMC449710
  • Shaffer ML, Chinchilli VM
    A likelihood-based, counterfactual approach to accounting for treatment failures in clinical trials.
    12921395 Journal of biopharmaceutical statistics , 2003 Aug. : 13(3)481-94