Profile

Lincoln S. Smith, MD

Lincoln S. Smith, MD

Critical Care, PICU

On staff since July 2006

Children's Title: Program Director Critical Care Medicine Fellowship

Academic Title: Assistant Professor

Research Center: Center for Clinical and Translational Research

"Working in the ICU at Seattle Children's Hospital is such an incredible privilege. From the "routine" postoperative admissions to the children with life-threatening infections, our attention to details and careful application of state-of-the-art care for children allow us the opportunity to give those children the best possible second chance in life. As a pediatric intensivist, I have had opportunities to interrupt death and prevent disability in the lives of otherwise healthy children. Every time I secure the airway of a child who cannot breathe, I feel privileged to have had the opportunity to prevent the unnecessary death of a child. "

Lincoln Smith, MD, is attending physician at Seattle Childrens Hospital and Harborview Medical Center and assistant professor of pediatrics at the University of Washington School of Medicine. He is the Program Director of the Pediatric Critical Care Medicine Fellowship. He earned his MD at the University of Wisconsin, in Madison, and completed his pediatrics residency at Childrens Hospital of Buffalo where he served as chief resident. Smith completed his pediatric critical care fellowship training at Seattle Childrens, and he is board certified in general pediatrics and pediatric critical care medicine.

Smiths laboratory research is at the Pulmonary Research Laboratories at Veterans Administration Puget Sound Medical Center in Seattle. Smith is investigating the role of lung development in ventilator-induced lung injury. He is focusing on molecular mechanisms by which juvenile mice are protected from synergistic inflammatory and injurious interactions between activation of innate immunity and mechanical ventilation in adult mice.

Overview

Board Certification(s)

Pediatrics
Pediatric Critical Care Medicine

Medical/Professional School

University of Wisconsin School of Medicine and Public Health, Madison

Residency

Pediatrics, Children's Hospital of Buffalo, Buffalo

Fellowship

Pediatric Critical Care Medicine, Children's Hospital and Regional Medical Center, Seattle

Clinical Interests

Respiratory failure Cardiorespiratory interactions

Research Description

My research involves investigation of the role of lung development in the pulmonary responses to innate immune activation and mechanical stretch.

Research Focus Area

Translational Research

Awards and Honors

Award Name Award Description Awarded By Award Date
 Pediatric Research Loan Repayment Program - NIH NIH - NHLBI Oct. 1, 2006 - Sept. 30, 2010

Publications

  • Smith LS, Gharib SA, Frevert CW, Martin TR
    Effects of Age on the Synergistic Interactions between Lipopolysaccharide and Mechanical Ventilation in Mice.
    American journal of respiratory cell and molecular biology , 2009 Nov. 9
  • Smith LS, Kajikawa O, Elson G, Wick M, Mongovin S, Kosco-Vilbois M, Martin TR, Frevert CW
    Effect of Toll-like receptor 4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin.
    Experimental lung research , 2008 June : 225-43

Research Funding

Grant Title Grantor Amount Award Date
Developmental Mechanisms in Acute Lung Injury NIH/NHLBI $588,500.00 Aug. 11, 2009