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Lincoln S. Smith, MD

Lincoln S. Smith, MD

Critical Care, PICU

On staff since July 2006

Children's Title: Program Director Critical Care Medicine Fellowship

Academic Title: Assistant Professor

Research Center: Center for Clinical and Translational Research

"Working in the ICU at Seattle Children's Hospital is such an incredible privilege. From the "routine" postoperative admissions to the children with life-threatening infections, our attention to details and careful application of state-of-the-art care for children allow us the opportunity to give those children the best possible second chance in life. As a pediatric intensivist, I have had opportunities to interrupt death and prevent disability in the lives of otherwise healthy children. Every time I secure the airway of a child who cannot breathe, I feel privileged to have had the opportunity to prevent the unnecessary death of a child. "


Board Certification(s)
Pediatric Critical Care Medicine
Medical/Professional School
University of Wisconsin School of Medicine and Public Health, Madison
Pediatrics, Children's Hospital of Buffalo, Buffalo
Pediatric Critical Care Medicine, Children's Hospital and Regional Medical Center, Seattle
Clinical Interests

Respiratory failure Cardiorespiratory interactions

Research Description

My research involves investigation of the role of lung development in the pulmonary responses to innate immune activation and mechanical stretch.

Research Focus Area

Translational Research

Awards and Honors

Award NameAward DescriptionAwarded ByAward Date
Pediatric Research Loan Repayment Program - NIHNIH - NHLBIOct. 1, 2006 - Sept. 30, 2010


Effects of Age on the Synergistic Interactions between Lipopolysaccharide and Mechanical Ventilation in Mice.
American journal of respiratory cell and molecular biology , 2009 Nov 9
Effect of Toll-like receptor 4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin.
Experimental lung research , 2008 Jun: 225-43

Research Funding

Grant TitleGrantorAmountAward Date
Developmental Mechanisms in Acute Lung InjuryNIH/NHLBI $588,500.00Aug. 11, 2009

Primary Office

Seattle Children's
MB.10.620 - Critical Care
4800 Sand Point Way NE
Seattle, WA 98105

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