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Julie R. Park, MD

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Julie R. Park, MD

Hematology-Oncology

On staff since October 1996

Children's Title: Program Director, Hematology / Oncology Education

Academic Title: Professor of Pediatrics, UW School of Medicine; Associate, Clinical Research Division, Fred Hutchinson Cancer Research Center

Research Center: Center for Clinical and Translational Research

Overview

Board Certification(s)
Pediatric Hematology-Oncology
Medical/Professional School
University of Vermont College of Medicine, Burlington
Clinical Interests

Neuroblastoma, Novel therapies, Supportive care guidelines for care of oncologic patients, Post-transplant lymphoproliferative disease

Research Description

I am an active member of the Children's Oncology Group (COG) Consortium, coordinating the center's participation in clinical trials for treatment of neuroblastoma and non-Hodgkin lymphoma. As the oncology division director of Advanced Developmental Therapeutics, I oversee participation in national NIH-funded Phase I clinical research consortia, including the COG Phase I Consortium and the New Approaches to Neuroblastoma Therapy (NANT) Consortium.

My primary research focus is to discover novel therapies for the treatment of high-risk pediatric neuroblastoma using both adoptive immunotherapy and novel molecularly targeted approaches. I am the principal investigator for a national randomized Phase III trial within COG for treatment of newly diagnosed high-risk neuroblastoma.

Research Focus Area

Cancer

Awards and Honors

Award NameAward DescriptionAwarded ByAward Date
U.S. News Top DoctorU.S. News and World Report 2012
Seattle Magazine Top Doctor - 2012Seattle Magazine Top Doctor - 2012Seattle Magazine 2012
Benjamin Towne Endowed Chair in NeuroblastomaBenjamin Towne FoundationJan. 1, 2009

Publications

Pediatric phase I trial and pharmacokinetic study of vorinostat: a Children's Oncology Group phase I consortium report.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2010 Aug 1: 3623-9
Neuroblastoma: biology, prognosis, and treatment.
Hematology/oncology clinics of North America , 2010 Feb: 65-86
High-risk neuroblastoma: a therapy in evolution.
Pediatric hematology and oncology , 2009 Nov: 539-48
Phase I trial of oral irinotecan and temozolomide for children with relapsed high-risk neuroblastoma: a new approach to neuroblastoma therapy consortium study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2009 Mar 10: 1290-6
Population pharmacokinetics of cyclophosphamide and metabolites in children with neuroblastoma: a report from the Children's Oncology Group.
Journal of clinical pharmacology , 2009 Jan: 88-102
Outcome of high-risk stage 3 neuroblastoma with myeloablative therapy and 13-cis-retinoic acid: a report from the Children's Oncology Group.
Pediatric blood & cancer , 2009 Jan: 44-50
Influenza-associated morbidity in children with cancer.
Pediatric blood & cancer , 2008 May: 983-7
Neuroblastoma: biology, prognosis, and treatment.
Pediatric clinics of North America , 2008 Feb: 97-120, x
Adoptive transfer of chimeric antigen receptor re-directed cytolytic T lymphocyte clones in patients with neuroblastoma.
Molecular therapy : the journal of the American Society of Gene Therapy , 2007 Apr: 825-33
Low-dose chemotherapy for Epstein-Barr virus-positive post-transplantation lymphoproliferative disease in children after solid organ transplantation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2005 Sep 20: 6481-8
Toxicity and efficacy of intensive chemotherapy for children with acute lymphoblastic leukemia (ALL) after first bone marrow or extramedullary relapse.
Pediatric blood & cancer , 2004 Oct: 571-9
Asparaginase pharmacokinetics after intensive polyethylene glycol-conjugated L-asparaginase therapy for children with relapsed acute lymphoblastic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research , 2004 Aug 15: 5335-41
Fractionated low-dose radiotherapy after myeloablative stem cell transplantation for local control in patients with high-risk neuroblastoma.
Cancer , 2004 Mar 15: 1268-75
Prolonged survival after invasive aspergillosis: a single-institution review of 11 cases.
Journal of pediatric hematology/oncology : official journal of the American Society of Pediatric Hematology/Oncology , 2003 Apr: 286-91
Ciprofloxacin and amoxicillin as continuation treatment of febrile neutropenia in pediatric cancer patients.
Medical and pediatric oncology , 2003 Feb: 93-8

Presentations

Presentations TitleEventLocationDate
Infectious Complications of Pediatric CancerAdvanced Oncology Nursing unknownOct. 1, 2009
Infectious Complications of Pediatric CancerAdvanced Oncology Nursing unknownJune 1, 2009
Accessing Novel Therapies and Navigating the Maze - The Pediatric Oncologist's PerspectiveAmerican Society of Clinical Oncology, Educational SessionOrlando, FLJune 1, 2009
Targeting Treatment to Improve Outcomes for Childhood CancerCircle of Care Symposium, Seattle Children’s HospitalSeattle, WAMay 1, 2009
Infectious Complications of Pediatric CancerAdvanced Oncology NursingunknownFeb. 1, 2009
Infectious Complications of Pediatric CancerAdvanced Oncology Nursing unknownFeb. 1, 2009

Research Funding

Grant TitleGrantorAmountAward Date
NIH-U10 CA098543-05NIHFeb. 28, 2009
NIH-U10 CA97452-05 NIHAug. 1, 2007
NIH-U10 CA97452-05 NIHAug. 1, 2007
Translation Research for Pediatric Solid Tumors Alex’s Lemonade Stand Foundation $200,000.00July 1, 2007
Phase I-II Safety & Exploratory Pharmacodynamic Study of Intravenous Temsirolimus (CCI-779) in Pediatric Subjects with Relapsed-Refractory Solid TumorsWyeth PharmaceuticalsJan. 17, 2007
NIH – Biology and Therapy of High Risk NeuroblastomaNIHJune 30, 2006
Genetic Predisposition to Chemotherapy Toxicity in Children Receiving Cyclophosphamide CHRMC Gift Income Genetic Predisposition to Chemotherapy Toxicity in Children Receiving Cyclophosphamide Endowment Oct. 1, 2005
NIH-U10 CA098543-05NIHFeb. 28
Targeted Hematopoietic Irradiation for Treatment of High Risk Neuroblastoma7. CHRMC Gift Income Targeted Hematopoietic Irradiation for Treatment of High Risk Neuroblastoma Endowment Dec. 1, 1999

Primary Office

Seattle Children's
MB.8.501 - Hematology-Oncology
4800 Sand Point Way NE
Seattle, WA 98105
206-987-2106

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