Profile

Jiang Zheng, PhD

Jiang Zheng, PhD

Academic Title: Associate Professor, Prinicipal Investigator

Research Center: Center for Developmental Therapeutics

Overview

Research Description

One of the research interests of my research group focuses on mechanisms of toxic action. Specifically, it includes:

(1) investigation of the biochemical interaction of electrophilic metabolites of xenobiotics with biomacromolecules, and the toxicological consequence of the chemical reactions; and

(2) development of biomarkers as a measure to refer and assess the exposure of individuals or populations to dietary, environmental or occupational chemical substances, providing a link between external exposures and internal dosimetry.

Another project ongoing in my laboratory is to design and synthesize isozyme-selective inhibitor of glutathione S-transferase to combat resistance to cancer chemotherapy. Over-expression of glutathione S-transferase is known to be one of the major factors responsible for the development of chemotherapy resistance.

Research Focus Area

Biochemistry, Molecular Biology, Chemistry

Publications

  • Jiang Z, Wang Z, Xu Y, Wang B, Huang W, Cai S
    Analysis of RGS2 expression and prognostic significance in stage II and III colorectal cancer.
    Bioscience reports , 2010 Dec. : 383-90
  • Dai J, Zhang F, Zheng J
    Detection of protein adduction derived from styrene oxide to cysteine residues by alkaline permethylation.
    Analytical biochemistry , 2010 Oct. 1 : 73-81
  • Zheng X, Yang D, Liu X, Wang N, Li B, Cao H, Lu Y, Wei G, Zhou H, Zheng J
    Identification of a new anti-LPS agent, geniposide, from Gardenia jasminoides Ellis, and its ability of direct binding and neutralization of lipopolysaccharide in vitro and in vivo.
    International immunopharmacology , 2010 Oct. : 1209-19
  • Deng P, Zhong D, Nan F, Liu S, Li D, Yuan T, Chen X, Zheng J
    Evidence for the Bioactivation of 4-Nonylphenol to Quinone Methide and ortho-Benzoquinone Metabolites in Human Liver Microsomes.
    Chemical research in toxicology , 2010 Sept. 15
  • Zhang S, Zhang L, Li H, Li J, Jiang Z, Chu W, Huang Y, Wang J, Wu Z
    Investigation of annealing-induced oxygen vacancies in the Co-doped ZnO system by Co K-edge XANES spectroscopy.
    Journal of synchrotron radiation , 2010 Sept. : 600-5
  • Shen S, Zhang F, Gao L, Zeng S, Zheng J
    Detection of phenolic metabolites of styrene in mouse liver and lung microsomal incubations.
    Drug metabolism and disposition: the biological fate of chemicals , 2010 Aug. 19
  • Yuan W, Jin H, Chung JK, Zheng J
    Evidence for cellular protein covalent binding derived from styrene metabolite.
    Chemico-biological interactions , 2010 Aug. 5 : 323-30
  • Jiang Z, Li C, Xu Y, Cai S, Wang X
    Associations between XPD polymorphisms and risk of breast cancer: a meta-analysis.
    Breast cancer research and treatment , 2010 Aug. : 203-12
  • Jiang Z, Xu Y, Cai S
    CXCL10 expression and prognostic significance in stage II and III colorectal cancer.
    Molecular biology reports , 2010 July : 3029-36
  • Liang G, Chen M, Pan XL, Zheng J, Wang H
    Ethanol-induced inhibition of fetal hypothalamic-pituitary-adrenal axis due to prenatal overexposure to maternal glucocorticoid in mice.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie , 2010 June 3
  • Li C, Jiang Z, Liu X
    Biochemical mechanism of gallium on prevention of fatal cage-layer osteoporosis.
    Biological trace element research , 2010 May : 195-202
  • Liu Y, Wu G, Fu H, Jiang Z, Chen S, Sha M
    Immobilization and melting point depression of imidazolium ionic liquids on the surface of nano-SiOx particles.
    Dalton transactions (Cambridge, England : 2003) , 2010 Apr, 7 : 3190-4
  • Wang X, He X, Jiang Z, Wang J, Chen X, Liu D, Wang F, Guo Y, Zhao J, Liu F, Huang L, Yuan J
    Proteomic analysis of the Enterococcus faecalis V583 strain and clinical isolate V309 under vancomycin treatment.
    Journal of proteome research , 2010 Apr, 5 : 1772-85
  • Li B, Li J, Pan X, Ding G, Cao H, Jiang W, Zheng J, Zhou H
    Artesunate protects sepsis model mice challenged with Staphylococcus aureus by decreasing TNF-alpha release via inhibition TLR2 and Nod2 mRNA expressions and transcription factor NF-kappaB activation.
    International immunopharmacology , 2010 Mar. : 344-50
  • Jin H, Dai J, Chen X, Liu J, Zhong D, Gu Y, Zheng J
    Pulmonary toxicity and metabolic activation of dauricine in CD-1 mice.
    The Journal of pharmacology and experimental therapeutics , 2010 Mar. : 738-46
  • Zhou J, Sun W, Zhou Z, Wu Y, Xiang TX, Jiang Z, Tao XH, Huang AL, Wang PL
    [Overexpression of adiponectin prevents hepatocyte steatosis]
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology , 2010 Mar. : 213-6
  • Ji F, Xi X, Han DY, Lin SL, Ye SN, Lin YH, Cui Y, Huang SM, Zhao WL, Yang YL, Wang YH, Jiang Z, Li YY, Chen G, Liu XL, Sun YH, Wang LY, Cao YM, Li J, Chang W, Li Y, Ren Y, Wu H
    [Test-retest reliability of Mandarin monosyllable lists: a multi-center study in Chinese dialectal regions]
    Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery , 2010 Mar. : 200-5
  • Jiang Z, Zhou W, Li XG, Jiang YQ, Wang L, Wang DH, Wang XY, Li XE
    [The methylation analysis of EMP3 and PCDH-gamma-A11 gene in human glioma]
    Zhonghua wai ke za zhi [Chinese journal of surgery] , 2010 Feb. 15 : 300-4
  • Jiang Z, Li C, Xu Y, Cai S
    A meta-analysis on XRCC1 and XRCC3 polymorphisms and colorectal cancer risk.
    International journal of colorectal disease , 2010 Feb. : 169-80
  • Jiang Z, Shen W
    Role of neurotransmitter receptors in mediating light-evoked responses in retinal interplexiform cells.
    Journal of neurophysiology , 2010 Feb. : 924-33
  • Xiao H, Tang J, Hu Z, Tan J, Tang B, Jiang Z
    [Polyglutamine-expanded ataxin-3 is degraded by autophagy]
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics , 2010 Feb. : 23-8
  • Cai Y, Li XC, Wu XM, Wang N, Cao HW, Wei G, Zhao KC, Zheng K, Zheng J, Li Y
    [Identification of HBV genotype-specific tag sequences]
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology , 2010 Feb. : 101-4
  • Dai J, Zhang F, Zheng J
    Retrorsine, but not monocrotaline, is a mechanism-based inactivator of P450 3A4.
    Chemico-biological interactions , 2010 Jan. 5 : 49-56
  • Li C, Jiang Z, Liu X
    XPD Lys(751)Gln and Asp (312)Asn polymorphisms and bladder cancer risk: a meta-analysis.
    Molecular biology reports , 2010 Jan. : 301-9
  • Zhang D, Chen J, Deng L, Mao Q, Zheng J, Wu J, Zeng C, Li Y
    Evolutionary selection associated with the multi-function of overlapping genes in the hepatitis B virus.
    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases , 2010 Jan. : 84-8
  • Mörbt N, Mögel I, Kalkhof S, Feltens R, Röder-Stolinski C, Zheng J, Vogt C, Lehmann I, von Bergen M
    Proteome changes in human bronchoalveolar cells following styrene exposure indicate involvement of oxidative stress in the molecular-response mechanism.
    Proteomics , 2009 Nov. : 4920-33
  • Yao J, Zheng JS, Fu W, Zheng J
    Extraction of the anti-sepsis component from Terminaliachebula Retz and evaluation of its biological activities.
    Bioscience reports , 2009 Oct. 6 : 27-32
  • Zheng J
    [Achievements and challenges in schistosomiasis control in China]
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2009 Oct. : 398-401
  • Liu X, Cheng J, Zheng X, Chen Y, Wu C, Li B, Fu J, Cao H, Lu Y, Li J, Zheng J, Zhou H
    Targeting CpG DNA to screen and isolate anti-sepsis fraction and monomers from traditional Chinese herbs using affinity biosensor technology.
    International immunopharmacology , 2009 Aug. : 1021-31
  • Xu J, Guo JG, Wu XH, Zeng XJ, Yang WP, Yang GB, Zheng J, Zhou XN
    [Efficacy and adverse effects of film coated praziquantel for treatment of schistosomiasis japonica]
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] , 2009 Aug. : 718-22
  • Jiang Z, Hao Z, Su J, Xiao T, Edwards PP
    Water/oil microemulsion for the preparation of robust La-hexaaluminates for methane catalytic combustion.
    Chemical communications (Cambridge, England) , 2009 June 14 : 3225-7
  • Li J, Piao YF, Jiang Z, Chen L, Sun HB
    Silencing of signal transducer and activator of transcription 3 expression by RNA interference suppresses growth of human hepatocellular carcinoma in tumor-bearing nude mice.
    World journal of gastroenterology : WJG , 2009 June 7 : 2602-8
  • Wang Y, Zhong D, Chen X, Zheng J
    Identification of quinone methide metabolites of dauricine in human liver microsomes and in rat bile.
    Chemical research in toxicology , 2009 May : 824-34
  • Li Y, Yao JF, Ma JB, Xu P, Zhang YM, Wang JW, Zheng J, Qin SQ
    [Clinial report of posterior approach for treatment of acetabular fracture]
    Zhongguo gu shang = China journal of orthopaedics and traumatology , 2009 May : 397-8
  • Shen S, Zhang F, Zeng S, Tian Y, Chai X, Gee S, Hammock BD, Zheng J
    Development of enantioselective polyclonal antibodies to detect styrene oxide protein adducts.
    Analytical chemistry , 2009 Apr, 1 : 2668-77
  • Shen S, Zhang F, Zeng S, Zheng J
    An approach based on liquid chromatography/electrospray ionization-mass spectrometry to detect diol metabolites as biomarkers of exposure to styrene and 1,3-butadiene.
    Analytical biochemistry , 2009 Mar. 15 : 186-93
  • Zou Y, Xu H, Wu G, Jiang Z, Chen S, Huang Y, Huang W, Wei X
    Structural analysis of [ChCl](m)[ZnCl(2)](n) ionic liquid by X-ray absorption fine structure spectroscopy.
    The journal of physical chemistry. B , 2009 Feb. 19 : 2066-70
  • Zhou W, Jiang Z, Li X, Xu F, Liu Y, Wen P, Kong L, Hou M, Yu J
    EMP3 overexpression in primary breast carcinomas is not associated with epigenetic aberrations.
    Journal of Korean medical science , 2009 Feb. : 97-103
  • Guo YB, Zheng QY, Chen JH, Cai SF, Cao HW, Zheng J, Xiao GX
    [Effect of mastoparan-1 on lipopolysaccharide-induced acute hepatic injury in mice]
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2009 Feb. : 53-6
  • Zhou W, Jiang Z, Liu N, Xu F, Wen P, Liu Y, Zhong W, Song X, Chang X, Zhang X, Wei G, Yu J
    Down-regulation of CXCL12 mRNA expression by promoter hypermethylation and its association with metastatic progression in human breast carcinomas.
    Journal of cancer research and clinical oncology , 2009 Jan. : 91-102
  • Jiang Z, Yang F, Luo N, Chu BT, Sun D, Shi H, Xiao T, Edwards PP
    Solvothermal synthesis of N-doped TiO2 nanotubes for visible-light-responsive photocatalysis.
    Chemical communications (Cambridge, England) , 2008 Dec. 21 : 6372-4
  • Fu J, Cao H, Wang N, Zheng X, Lu Y, Liu X, Yang D, Li B, Zheng J, Zhou H
    An anti-sepsis monomer, 2',5,6',7-tetrahydroxyflavanonol (THF), identified from Scutellaria baicalensis Georgi neutralizes lipopolysaccharide in vitro and in vivo.
    International immunopharmacology , 2008 Dec. 10 : 1652-7
  • He X, Liu D, Sun Z, Wang F, Jiang Z, Zhao H, Chen X, Huang L, Yuan J
    [Proteomic analysis of Bifidobacteria longum strain NCC2705 grown on lactose and glucose]
    Wei sheng wu xue bao = Acta microbiologica Sinica , 2008 Nov. 4 : 1451-8
  • Shen W, Jiang Z, Li B
    Glycine input induces the synaptic facilitation in salamander rod photoreceptors.
    Journal of biomedical science , 2008 Nov. : 743-54
  • Zhou W, Jiang Z, Song X, Liu Y, Wen P, Guo Y, Xu F, Kong L, Zhang P, Han A, Yu J
    Promoter hypermethylation-mediated down-regulation of CXCL12 in human astrocytoma.
    Journal of neuroscience research , 2008 Oct. : 3002-10
  • Wu XH, Zhang SQ, Xu XJ, Huang YX, Steinmann P, Utzinger J, Wang TP, Xu J, Zheng J, Zhou XN
    Effect of floods on the transmission of schistosomiasis in the Yangtze River valley, People's Republic of China.
    Parasitology international , 2008 Sept. : 271-6
  • Sun Z, Bo X, He X, Jiang Z, Wang F, Zhao H, Liu D, Yuan J
    [Comparative proteome analysis of Bifidobacterium longum NCC2705 grown on fructose and glucose]
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology , 2008 Aug. : 1401-6
  • Xiang TX, Li Y, Jiang Z, Huang AL, Luo C, Zhan B, Wang PL, Tao XH
    RNA interference-mediated silencing of the Hsp70 gene inhibits human gastric cancer cell growth and induces apoptosis in vitro and in vivo.
    Tumori , 2008 July : 539-50
  • Wang W, Xia CQ, Liu N, Gan LS, Zheng J
    Mechanistic study of potentiation of chemotherapy by a haloenol lactone derivative in vitro.
    Cancer chemotherapy and pharmacology , 2008 June : 117-22
  • Li B, Zhang R, Li J, Zhang L, Ding G, Luo P, He S, Dong Y, Jiang W, Lu Y, Cao H, Zheng J, Zhou H
    Antimalarial artesunate protects sepsis model mice against heat-killed Escherichia coli challenge by decreasing TLR4, TLR9 mRNA expressions and transcription factor NF-kappa B activation.
    International immunopharmacology , 2008 Mar. : 379-89
  • Wu XH, Zhang SQ, Wang TP, Xu J, Zhou XN, Wang RB, Zheng J
    [Schistosomiasis transmission in areas where inhabitants migrated from outside embankment to new settlement]
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2008 Feb. 28 : 16-20
  • Yao XH, Ping YF, Chen JH, Chen DL, Xu CP, Zheng J, Wang JM, Bian XW
    Production of angiogenic factors by human glioblastoma cells following activation of the G-protein coupled formylpeptide receptor FPR.
    Journal of neuro-oncology , 2008 Jan. : 47-53
  • Yao XH, Ping YF, Chen JH, Chen DL, Xu CP, Zheng J, Wang JM, Bian XW
    Production of angiogenic factors by human glioblastoma cells following activation of the G-protein coupled formylpeptide receptor FPR.
    Journal of neuro-oncology , 2008 Jan. : 47-53
  • Yuan J, Wang B, Sun Z, Bo X, Yuan X, He X, Zhao H, Du X, Wang F, Jiang Z, Zhang L, Jia L, Wang Y, Wei K, Wang J, Zhang X, Sun Y, Huang L, Zeng M
    Analysis of host-inducing proteome changes in bifidobacterium longum NCC2705 grown in Vivo.
    Journal of proteome research , 2008 Jan. : 375-85
  • Zheng J, Guan RZ, Huang SY
    [Comparative studies on the characteristics of the Fourier-transform infrared spectra between sturgeon and shark chondroitin sulfates]
    Guang pu xue yu guang pu fen xi = Guang pu , 2008 Jan. : 106-9
  • Luo P, Xie G, Jiang Z
    [The progress in researches on biocompatibility for direct brain-machine interface]
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi , 2007 Dec. : 1416-8
  • Yi JP, Fan ZG, Jiang ZW, Li WS, Zhou XP
    High-throughput parallel reactor system for propylene oxidation catalyst investigation.
    Journal of combinatorial chemistry , 2007 Nov. : 1053-9
  • Zhou XN, Guo JG, Wu XH, Jiang QW, Zheng J, Dang H, Wang XH, Xu J, Zhu HQ, Wu GL, Li YS, Xu XJ, Chen HG, Wang TP, Zhu YC, Qiu DC, Dong XQ, Zhao GM, Zhang SJ, Zhao NQ, Xia G, Wang LY, Zhang SQ, Lin DD, Chen MG, Hao Y
    Epidemiology of schistosomiasis in the People's Republic of China, 2004.
    Emerging infectious diseases , 2007 Oct. : 1470-6
  • Wang W, Liu G, Zheng J
    Human renal UOK130 tumor cells: a drug resistant cell line with highly selective over-expression of glutathione S-transferase-pi isozyme.
    European journal of pharmacology , 2007 July 30 : 61-7
  • Wang W, Liu G, Zheng J
    Human renal UOK130 tumor cells: a drug resistant cell line with highly selective over-expression of glutathione S-transferase-pi isozyme.
    European journal of pharmacology , 2007 July 30 : 61-7
  • Huang Q, Baum L, Huang JF, You JP, Wang F, Wang J, Zheng J, Yan XC, Xia H, Zhao YH, Kuang H, Fu WL
    Isolation and enrichment of human genomic CpG islands by methylation-sensitive mirror orientation selection.
    Analytical biochemistry , 2007 June 15 : 153-64
  • Huang Q, Baum L, Huang JF, You JP, Wang F, Wang J, Zheng J, Yan XC, Xia H, Zhao YH, Kuang H, Fu WL
    Isolation and enrichment of human genomic CpG islands by methylation-sensitive mirror orientation selection.
    Analytical biochemistry , 2007 June 15 : 153-64
  • Guo YB, Chen LP, Cao HW, Wang N, Zheng J, Xiao GX
    Polymyxin B antagonizing biological activity of lipopolysaccharide.
    Chinese journal of traumatology = Zhonghua chuang shang za zhi / Chinese Medical Association , 2007 June : 180-3
  • Guo YB, Chen LP, Cao HW, Wang N, Zheng J, Xiao GX
    Polymyxin B antagonizing biological activity of lipopolysaccharide.
    Chinese journal of traumatology = Zhonghua chuang shang za zhi / Chinese Medical Association , 2007 June : 180-3
  • Xu J, Chen NG, Feng T, Wang EM, Wu XH, Chen HG, Wang TP, Zhou XN, Zheng J
    [Effectiveness of routinely used assays for the diagnosis of schistosomiasis japonica in the field]
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2007 June : 175-9
  • Wang L, Jiang W, Ding G, Cao H, Lu Y, Luo P, Zhou H, Zheng J
    The newly identified CpG-N ODN208 protects mice from challenge with CpG-S ODN by decreasing TNF-alpha release.
    International immunopharmacology , 2007 May : 646-55
  • Wang WL, Zhang HZ, Cai ZD, Qin Q, Liu FC, Xu XJ, Wei FH, Zheng J
    [Evaluation on schistosomiasis control effect of the intervention measures adapted to the ecological environment changes in Jiang Han Plain due to establishment of the Three Gorges dam]
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2007 Apr, 30 : 114-9
  • Wen LY, Lu SH, Chen JH, Zhang JF, Yu LL, Ding JZ, Yan XL, Shen LY, Zheng W, Gao LL, Wang TP, Zhang SQ, Chen GX, Ye Y, Zhou XN, Zheng J
    [Observation on the change of anti-S. japonicum antibody level in population migrated from outside embankment to new town]
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2007 Apr, 30 : 146-9
  • Lin G, Tang J, Liu XQ, Jiang Y, Zheng J
    Deacetylclivorine: a gender-selective metabolite of clivorine formed in female Sprague-Dawley rat liver microsomes.
    Drug metabolism and disposition: the biological fate of chemicals , 2007 Apr, : 607-13
  • Yang J, Nugroho AS, Yamauchi K, Yoshioka K, Zheng J, Wang K, Kato K, Kuroyanagi S, Iwata A
    Efficacy of interferon treatment for chronic hepatitis C predicted by feature subset selection and support vector machine.
    Journal of medical systems , 2007 Apr, : 117-23
  • Yang J, Nugroho AS, Yamauchi K, Yoshioka K, Zheng J, Wang K, Kato K, Kuroyanagi S, Iwata A
    Efficacy of interferon treatment for chronic hepatitis C predicted by feature subset selection and support vector machine.
    Journal of medical systems , 2007 Apr, : 117-23
  • Guo YB, Cao HW, Chen LP, Lu YL, Zheng J, Xiao GX
    [Study of lipopolysaccharide antagonizing effect of DPR-2 in vitro]
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2007 Apr, : 104-7
  • Jiang Z, Li B, Jursky F, Shen W
    Differential distribution of glycine transporters in Müller cells and neurons in amphibian retinas.
    Visual neuroscience , 2007 Mar. : 157-68
  • Yuan W, Chung J, Gee S, Hammock BD, Zheng J
    Development of polyclonal antibodies for the detection of styrene oxide modified proteins.
    Chemical research in toxicology , 2007 Feb. : 316-21
  • Jiang Z, Li XG, Hu J, Lu DR, Zhou W, Jiang YQ, Li CY
    [The methylation and mRNA expression of SLC5A8 and TMS1/ASC genes in human glioma]
    Zhonghua yi xue za zhi , 2007 Jan. 30 : 292-7
  • Jiang Z, Li XG, Hu J, Lu DR, Zhou W, Jiang YQ, Li CY
    [The methylation and mRNA expression of SLC5A8 and TMS1/ASC genes in human glioma]
    Zhonghua yi xue za zhi , 2007 Jan. 30 : 292-7
  • Shen W, Jiang Z
    Characterization of glycinergic synapses in vertebrate retinas.
    Journal of biomedical science , 2007 Jan. : 5-13
  • Jiang Z, Hu J, Li X, Jiang Y, Zhou W, Lu D
    Expression analyses of 27 DNA repair genes in astrocytoma by TaqMan low-density array.
    Neuroscience letters , 2006 Dec. 1 : 112-7
  • Jiang Z, Li X, Hu J, Zhou W, Jiang Y, Li G, Lu D
    Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma.
    Neuroscience research , 2006 Dec. : 450-8
  • Sun W, Jiang Z, Wang PL
    [Effect of adiponectin on nonalcoholic fatty liver disease]
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology , 2006 Dec. : 952-4
  • Yi JP, Huang L, Jiang ZW, Li WS, Zhou XP
    Colorimetric diffusion-reflection imaging high-throughput analysis of organic or inorganic compounds.
    Journal of combinatorial chemistry , 2006 Nov. : 881-9
  • Jiang Z, Yamauchi K, Yoshioka K, Aoki K, Kuroyanagi S, Iwata A, Yang J, Wang K
    Support vector machine-based feature selection for classification of liver fibrosis grade in chronic hepatitis C.
    Journal of medical systems , 2006 Oct. : 389-94
  • Chung JK, Yuan W, Liu G, Zheng J
    Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells.
    Toxicology , 2006 Sept. 21 : 99-106
  • Wang J, Zhou H, Zheng J, Cheng J, Liu W, Ding G, Wang L, Luo P, Lu Y, Cao H, Yu S, Li B, Zhang L
    The antimalarial artemisinin synergizes with antibiotics to protect against lethal live Escherichia coli challenge by decreasing proinflammatory cytokine release.
    Antimicrobial agents and chemotherapy , 2006 July : 2420-7
  • Wei L, Hong Z, Jiang Z, Guofu D, Hongwei C, Liangxi W, Yongling L, Bin L, Ping L
    Decreased intracellular TLR9 confers hyporesponsiveness of RAW264.7 cells to subsequent CpG ODN challenge.
    International immunopharmacology , 2006 June : 935-46
  • Yu JJ, Jiang Z, Zhu L, Hao ZP, Xu ZP
    Adsorption/desorption studies of NOx on well-mixed oxides derived from Co-Mg/Al Hydrotalcite-like compounds.
    The journal of physical chemistry. B , 2006 Mar. 9 : 4291-300
  • Zheng JY, Zhou Y, Milli P
    Scanning scene tunnel for city traversing.
    IEEE transactions on visualization and computer graphics , 2006 Mar. : 155-67
  • Huang D, Yamauchi K, Inden Y, Yang J, Jiang Z, Ida H, Katsuyama K, Wang K, Kato K, Kato H
    Use of an artificial neural network to localize accessory pathways of Wolff-Parkinson-White syndrome with 12-lead electrocardiogram.
    Medical informatics and the Internet in medicine , 2005 Dec. : 277-86
  • Zhou XN, Wang LY, Chen MG, Wu XH, Jiang QW, Chen XY, Zheng J, Utzinger J
    The public health significance and control of schistosomiasis in China--then and now.
    Acta tropica , 2005 Nov. : 97-105
  • Zhou XN, Wang LY, Chen MG, Wang TP, Guo JG, Wu XH, Jiang QW, Zheng J, Chen XY
    An economic evaluation of the national schistosomiasis control programme in China from 1992 to 2000.
    Acta tropica , 2005 Nov. : 255-65
  • Wu XH, Chen MG, Zheng J
    Surveillance of schistosomiasis in five provinces of China which have reached the national criteria for elimination of the disease.
    Acta tropica , 2005 Nov. : 276-81
  • Wen LY, Chen JH, Ding JZ, Zhang JF, Lu SH, Yu LL, Shen LY, Wu GL, Zhou XN, Zheng J
    Evaluation on the applied value of the dot immunogold filtration assay (DIGFA) for rapid detection of anti-Schistosoma japonicum antibody.
    Acta tropica , 2005 Nov. : 142-7
  • Lv GF, Xiao GX, Wei G, Guo YB, Zheng J
    [Study of the anti-endotoxin effect of beta-1, 2, 3, 4, 6-penta-O-galloyl-D-glucopyranose in vitro]
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2005 Aug. : 282-4
  • Yibin G, Jiang Z, Hong Z, Gengfa L, Liangxi W, Guo W, Yongling L
    A synthesized cationic tetradecapeptide from hornet venom kills bacteria and neutralizes lipopolysaccharide in vivo and in vitro.
    Biochemical pharmacology , 2005 July 15 : 209-19
  • Genfa L, Jiang Z, Hong Z, Yimin Z, Liangxi W, Guo W, Ming H, Donglen J, Lizhao W
    The screening and isolation of an effective anti-endotoxin monomer from Radix Paeoniae Rubra using affinity biosensor technology.
    International immunopharmacology , 2005 June : 1007-17
  • Guo YB, Zheng J, Lv GF, Wei G, Wang LX, Xiao GX
    [Experimental study on the antagonistic activity of cationic multi-peptide mastoparan-1 against lipopolysaccharide]
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2005 June : 189-92
  • Li JJ, Xu XY, Jiang Z, Hao ZP, Hu C
    Nanoporous silica-supported nanometric palladium: synthesis, characterization, and catalytic deep oxidation of benzene.
    Environmental science & technology , 2005 Mar. 1 : 1319-23
  • Zheng J, Liu G, Tozkoparan B, Wen D
    Mechanistic studies of inactivation of glutathione S-transferase Pi isozyme by a haloenol lactone derivative.
    Medicinal chemistry (Shariqah (United Arab Emirates)) , 2005 Mar. : 191-8
  • Dong Y, Zheng J, Wang XY, Zhou J
    [Effect of oxygen therapy for injury of intestinal mucosal barrier of rabbits in high altitude hemorrhagic shock.]
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue , 2005 Jan. : 32-5
  • Xianyi C, Liying W, Jiming C, Xiaonong Z, Jiang Z, Jiagang G, Xiaohua W, Engels D, Minggang C
    Schistosomiasis control in China: the impact of a 10-year World Bank Loan Project (1992-2001).
    Bulletin of the World Health Organization , 2005 Jan. : 43-8
  • Alvarez-Diez TM, Zheng J
    Detection of glutathione conjugates derived from 4-ipomeanol metabolism in bile of rats by liquid chromatography-tandem mass spectrometry.
    Drug metabolism and disposition: the biological fate of chemicals , 2004 Dec. : 1345-50
  • Jiang Z, Huang AL, Tao XH, Wang PL
    Diagnosis of Helicobacter pylori infection and diseases associated with Helicobacter pylori by Helicobacter pylori outer membrane proteins.
    World journal of gastroenterology : WJG , 2004 Dec. 1 : 3464-9
  • Chen DR, Huang AL, Tao XH, Wang PL, Jiang Z
    Cloning and sequence analysis of gene oipA encoding an outer membrane protein of human Helicobacter pylori.
    World journal of gastroenterology : WJG , 2004 Nov. 1 : 3205-7
  • Zhou H, Ding G, Liu W, Wang L, Lu Y, Cao H, Zheng J
    Lipopolysaccharide could be internalized into human peripheral blood mononuclear cells and elicit TNF-alpha release, but not via the pathway of toll-like receptor 4 on the cell surface.
    Cellular & molecular immunology , 2004 Oct. : 373-7
  • Xu XJ, Wei FH, Cai SX, Liu JB, Fu Y, Zheng J, Wang RB, Zhou XN, Liu GY, Wang KY, Sun B
    [Study on the risk factors of schistosomiasis transmission and control strategy in the Three Gorges Reservoir Areas]
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi , 2004 July : 559-63
  • Wu Z, Minhas GS, Wen D, Jiang H, Chen K, Zimniak P, Zheng J
    Design, synthesis, and structure-activity relationships of haloenol lactones: site-directed and isozyme-selective glutathione S-transferase inhibitors.
    Journal of medicinal chemistry , 2004 June 3 : 3282-94
  • Jiang Z, Hong Z, Guo W, Xiaoyun G, Gengfa L, Yongning L, Guangxia X
    A synthetic peptide derived from bactericidal/permeability-increasing protein neutralizes endotoxin in vitro and in vivo.
    International immunopharmacology , 2004 Apr, : 527-37
  • Alvarez-Diez TM, Zheng J
    Mechanism-based inactivation of cytochrome P450 3A4 by 4-ipomeanol.
    Chemical research in toxicology , 2004 Feb. : 150-7
  • Hong Z, Jiang Z, Liangxi W, Guofu D, Ping L, Yongling L, Wendong P, Minghai W
    Chloroquine protects mice from challenge with CpG ODN and LPS by decreasing proinflammatory cytokine release.
    International immunopharmacology , 2004 Feb. : 223-34
  • Lu GF, Gong XY, Wei G, Wang N, Xiao GX, Zheng J
    [Study of biosensor technology on the detection of endotoxin-neutralizing materials]
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2004 Feb. : 23-5
  • Li C, Du F, Yu C, Xu X, Zheng J, Xu F, Zhu D
    A sensitive method for the determination of the novel cholinesterase inhibitor ZT-1 and its active metabolite huperzine A in rat blood using liquid chromatography/tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM , 2004 : 651-6
  • Hao ZP, Hu C, Jiang Z, Lu GQ
    Preparation and catalytic properties of ZrO2-Al2O3 composite oxide supported nickel catalysts for methane reforming with carbon dioxide.
    Journal of environmental sciences (China) , 2004 : 316-20
  • Jiang Z, Huang AL, Pu D, Tao XH, Wang PL
    [Construction, expression and antigenicity of bivalent vaccine candidate of human Helicobacter pylori]
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology , 2004 Jan. : 62-6
  • Jiang Z, Huang AL, Tao XH, Wang PL
    Construction and characterization of bivalent vaccine candidate expressing HspA and M(r)18,000 OMP from Helicobacter pylori.
    World journal of gastroenterology : WJG , 2003 Aug. : 1756-61
  • Jiang Z, Pu D, Huang AL, Tao XH, Wang PL
    [Construction, expression and antigenic study of bivalent vaccine candidate with 26,000 OMP and heat short protein A of human Helicobacter pylori]
    Zhonghua yi xue za zhi , 2003 May 25 : 862-7
  • Zhou H, Zheng J, Lu YL, Qin XJ, Xiao GX
    [The expression and analysis of its activity of anti-bacterial peptide gloverin in COS-7 cells]
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2003 Apr, : 86-8
  • Zheng J
    [Schistosomiasis control in China: progress and challenges]
    Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2003 : 4-5
  • Xia PY, Zheng J, Zhou H, Pan WD, Qin XJ, Xiao GX
    Relationship between lymphocyte apoptosis and endotoxin translocation after thermal injury in rats.
    World journal of gastroenterology : WJG , 2002 June : 546-50
  • Zheng J, Gu XG, Xu YL, Ge JH, Yang XX, He CH, Tang C, Cai KP, Jiang QW, Liang YS, Wang TP, Xu XJ, Zhong JH, Yuan HC, Zhou XN
    Relationship between the transmission of schistosomiasis japonica and the construction of the Three Gorge Reservoir.
    Acta tropica , 2002 May : 147-56
  • Xiao S, Tanner M, N'Goran EK, Utzinger J, Chollet J, Bergquist R, Chen M, Zheng J
    Recent investigations of artemether, a novel agent for the prevention of schistosomiasis japonica, mansoni and haematobia.
    Acta tropica , 2002 May : 175-81
  • Wu XH, Wang TP, Lu DB, Hu HT, Gao ZB, Zhu CG, Fang GR, He YC, Mei QJ, Wu WD, Ge JH, Zheng J
    Studies of impact on physical fitness and working capacity of patients with advanced Schistosomiasis japonica in Susong County, Anhui Province.
    Acta tropica , 2002 May : 247-52
  • Jiang Z, Tao XH, Huang AL, Wang PL
    A study of recombinant protective H.pylori antigens.
    World journal of gastroenterology : WJG , 2002 Apr, : 308-11
  • Guo J, Lin D, Hu G, Ning A, Liu H, Lu S, Li D, Wu X, Wang R, Chen M, Zheng J, Tanner M
    [Rapid identification of Oncomelania hupensis snail habitat in the Poyang Lake region by Geographic Information System (GIS) and Remote Sensing (RS)]
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi , 2002 Apr, : 99-101
  • Xu N, Yuan J, Xiao G, Zheng J, Qin X
    [An experimental study of the LPS release from gram-negative bacteria induced by antibiotics (Part two)]
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2002 Apr, : 92-4
  • Zheng J, Zhou H, Lu Y, Xiao G
    [The study on the role of modeling peptides derived from bactericidal/permeability increasing protein on the endotoxin neutralization]
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2002 Apr, : 95-8

Presentations

Presentations Title Event Location Date
Bioactivation and toxicity of natural products bisbenzylisoquinone alkaloids 9th Chinese National Conference on Drug and Xenobiotic Metabolism China Nov. 1, 2009
Targeting Glutathione S-Transferase: A Strategy to Combat Chemotherapy Resistance Chinese Medicinal Chemistry Symposium China Nov. 1, 2009
Haloenol Lactone: A Site-Directed Irreversible Inhibitor of Glutathione S-Transferase as a Modulator to Combat Drug Resistance in Chemotherapy School of Pharmaceutical Engineering, Shenyang Pharmaceutical University China Nov. 1, 2009
Bioactivation and pulmonary toxicity of bisbenzylisoquinone alkaloids Institute of Traditional Chinese Medicine, Shanghai University of Traditional Medicine Shanghai, China Oct. 1, 2009
Targeting Glutathione S-Transferase: A Strategy to Combat Chemotherapy Resistance School of Basic Medical Science, Wuhan University China April 1, 2009