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Jiang Zheng, PhD

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Jiang Zheng, PhD

Academic Title: Associate Professor, Prinicipal Investigator

Research Center: Center for Developmental Therapeutics

Overview

Research Description

One of the research interests of my research group focuses on mechanisms of toxic action. Specifically, it includes:

(1) investigation of the biochemical interaction of electrophilic metabolites of xenobiotics with biomacromolecules, and the toxicological consequence of the chemical reactions; and

(2) development of biomarkers as a measure to refer and assess the exposure of individuals or populations to dietary, environmental or occupational chemical substances, providing a link between external exposures and internal dosimetry.

Another project ongoing in my laboratory is to design and synthesize isozyme-selective inhibitor of glutathione S-transferase to combat resistance to cancer chemotherapy. Over-expression of glutathione S-transferase is known to be one of the major factors responsible for the development of chemotherapy resistance.

Research Focus Area

Biochemistry, Molecular Biology, Chemistry

Publications

Analysis of RGS2 expression and prognostic significance in stage II and III colorectal cancer.
Bioscience reports , 2010 Dec: 383-90
Identification of a new anti-LPS agent, geniposide, from Gardenia jasminoides Ellis, and its ability of direct binding and neutralization of lipopolysaccharide in vitro and in vivo.
International immunopharmacology , 2010 Oct: 1209-19
Detection of protein adduction derived from styrene oxide to cysteine residues by alkaline permethylation.
Analytical biochemistry , 2010 Oct 1: 73-81
Evidence for the Bioactivation of 4-Nonylphenol to Quinone Methide and ortho-Benzoquinone Metabolites in Human Liver Microsomes.
Chemical research in toxicology , 2010 Sep 15
Investigation of annealing-induced oxygen vacancies in the Co-doped ZnO system by Co K-edge XANES spectroscopy.
Journal of synchrotron radiation , 2010 Sep: 600-5
Detection of phenolic metabolites of styrene in mouse liver and lung microsomal incubations.
Drug metabolism and disposition: the biological fate of chemicals , 2010 Aug 19
Evidence for cellular protein covalent binding derived from styrene metabolite.
Chemico-biological interactions , 2010 Aug 5: 323-30
Associations between XPD polymorphisms and risk of breast cancer: a meta-analysis.
Breast cancer research and treatment , 2010 Aug: 203-12
CXCL10 expression and prognostic significance in stage II and III colorectal cancer.
Molecular biology reports , 2010 Jul: 3029-36
Ethanol-induced inhibition of fetal hypothalamic-pituitary-adrenal axis due to prenatal overexposure to maternal glucocorticoid in mice.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie , 2010 Jun 3
Biochemical mechanism of gallium on prevention of fatal cage-layer osteoporosis.
Biological trace element research , 2010 May: 195-202
Immobilization and melting point depression of imidazolium ionic liquids on the surface of nano-SiOx particles.
Dalton transactions (Cambridge, England : 2003) , 2010 Apr 7: 3190-4
Proteomic analysis of the Enterococcus faecalis V583 strain and clinical isolate V309 under vancomycin treatment.
Journal of proteome research , 2010 Apr 5: 1772-85
[Test-retest reliability of Mandarin monosyllable lists: a multi-center study in Chinese dialectal regions]
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery , 2010 Mar: 200-5
[Overexpression of adiponectin prevents hepatocyte steatosis]
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology , 2010 Mar: 213-6
Pulmonary toxicity and metabolic activation of dauricine in CD-1 mice.
The Journal of pharmacology and experimental therapeutics , 2010 Mar: 738-46
Artesunate protects sepsis model mice challenged with Staphylococcus aureus by decreasing TNF-alpha release via inhibition TLR2 and Nod2 mRNA expressions and transcription factor NF-kappaB activation.
International immunopharmacology , 2010 Mar: 344-50
[The methylation analysis of EMP3 and PCDH-gamma-A11 gene in human glioma]
Zhonghua wai ke za zhi [Chinese journal of surgery] , 2010 Feb 15: 300-4
[Identification of HBV genotype-specific tag sequences]
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology , 2010 Feb: 101-4
[Polyglutamine-expanded ataxin-3 is degraded by autophagy]
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics , 2010 Feb: 23-8
Role of neurotransmitter receptors in mediating light-evoked responses in retinal interplexiform cells.
Journal of neurophysiology , 2010 Feb: 924-33
A meta-analysis on XRCC1 and XRCC3 polymorphisms and colorectal cancer risk.
International journal of colorectal disease , 2010 Feb: 169-80
Retrorsine, but not monocrotaline, is a mechanism-based inactivator of P450 3A4.
Chemico-biological interactions , 2010 Jan 5: 49-56
Evolutionary selection associated with the multi-function of overlapping genes in the hepatitis B virus.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases , 2010 Jan: 84-8
XPD Lys(751)Gln and Asp (312)Asn polymorphisms and bladder cancer risk: a meta-analysis.
Molecular biology reports , 2010 Jan: 301-9
Proteome changes in human bronchoalveolar cells following styrene exposure indicate involvement of oxidative stress in the molecular-response mechanism.
Proteomics , 2009 Nov: 4920-33
Extraction of the anti-sepsis component from Terminaliachebula Retz and evaluation of its biological activities.
Bioscience reports , 2009 Oct 6: 27-32
[Achievements and challenges in schistosomiasis control in China]
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2009 Oct: 398-401
[Efficacy and adverse effects of film coated praziquantel for treatment of schistosomiasis japonica]
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] , 2009 Aug: 718-22
Targeting CpG DNA to screen and isolate anti-sepsis fraction and monomers from traditional Chinese herbs using affinity biosensor technology.
International immunopharmacology , 2009 Aug: 1021-31
Water/oil microemulsion for the preparation of robust La-hexaaluminates for methane catalytic combustion.
Chemical communications (Cambridge, England) , 2009 Jun 14: 3225-7
Silencing of signal transducer and activator of transcription 3 expression by RNA interference suppresses growth of human hepatocellular carcinoma in tumor-bearing nude mice.
World journal of gastroenterology : WJG , 2009 Jun 7: 2602-8
[Clinial report of posterior approach for treatment of acetabular fracture]
Zhongguo gu shang = China journal of orthopaedics and traumatology , 2009 May: 397-8
Identification of quinone methide metabolites of dauricine in human liver microsomes and in rat bile.
Chemical research in toxicology , 2009 May: 824-34
Development of enantioselective polyclonal antibodies to detect styrene oxide protein adducts.
Analytical chemistry , 2009 Apr 1: 2668-77
An approach based on liquid chromatography/electrospray ionization-mass spectrometry to detect diol metabolites as biomarkers of exposure to styrene and 1,3-butadiene.
Analytical biochemistry , 2009 Mar 15: 186-93
Structural analysis of [ChCl](m)[ZnCl(2)](n) ionic liquid by X-ray absorption fine structure spectroscopy.
The journal of physical chemistry. B , 2009 Feb 19: 2066-70
[Effect of mastoparan-1 on lipopolysaccharide-induced acute hepatic injury in mice]
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2009 Feb: 53-6
EMP3 overexpression in primary breast carcinomas is not associated with epigenetic aberrations.
Journal of Korean medical science , 2009 Feb: 97-103
Down-regulation of CXCL12 mRNA expression by promoter hypermethylation and its association with metastatic progression in human breast carcinomas.
Journal of cancer research and clinical oncology , 2009 Jan: 91-102
Solvothermal synthesis of N-doped TiO2 nanotubes for visible-light-responsive photocatalysis.
Chemical communications (Cambridge, England) , 2008 Dec 21: 6372-4
An anti-sepsis monomer, 2',5,6',7-tetrahydroxyflavanonol (THF), identified from Scutellaria baicalensis Georgi neutralizes lipopolysaccharide in vitro and in vivo.
International immunopharmacology , 2008 Dec 10: 1652-7
[Proteomic analysis of Bifidobacteria longum strain NCC2705 grown on lactose and glucose]
Wei sheng wu xue bao = Acta microbiologica Sinica , 2008 Nov 4: 1451-8
Glycine input induces the synaptic facilitation in salamander rod photoreceptors.
Journal of biomedical science , 2008 Nov: 743-54
Promoter hypermethylation-mediated down-regulation of CXCL12 in human astrocytoma.
Journal of neuroscience research , 2008 Oct: 3002-10
Effect of floods on the transmission of schistosomiasis in the Yangtze River valley, People's Republic of China.
Parasitology international , 2008 Sep: 271-6
[Comparative proteome analysis of Bifidobacterium longum NCC2705 grown on fructose and glucose]
Sheng wu gong cheng xue bao = Chinese journal of biotechnology , 2008 Aug: 1401-6
RNA interference-mediated silencing of the Hsp70 gene inhibits human gastric cancer cell growth and induces apoptosis in vitro and in vivo.
Tumori , 2008 Jul-Aug: 539-50
Mechanistic study of potentiation of chemotherapy by a haloenol lactone derivative in vitro.
Cancer chemotherapy and pharmacology , 2008 Jun: 117-22
Antimalarial artesunate protects sepsis model mice against heat-killed Escherichia coli challenge by decreasing TLR4, TLR9 mRNA expressions and transcription factor NF-kappa B activation.
International immunopharmacology , 2008 Mar: 379-89
[Schistosomiasis transmission in areas where inhabitants migrated from outside embankment to new settlement]
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2008 Feb 28: 16-20
[Comparative studies on the characteristics of the Fourier-transform infrared spectra between sturgeon and shark chondroitin sulfates]
Guang pu xue yu guang pu fen xi = Guang pu , 2008 Jan: 106-9
Analysis of host-inducing proteome changes in bifidobacterium longum NCC2705 grown in Vivo.
Journal of proteome research , 2008 Jan: 375-85
Production of angiogenic factors by human glioblastoma cells following activation of the G-protein coupled formylpeptide receptor FPR.
Journal of neuro-oncology , 2008 Jan: 47-53
Production of angiogenic factors by human glioblastoma cells following activation of the G-protein coupled formylpeptide receptor FPR.
Journal of neuro-oncology , 2008 Jan: 47-53
[The progress in researches on biocompatibility for direct brain-machine interface]
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi , 2007 Dec: 1416-8
High-throughput parallel reactor system for propylene oxidation catalyst investigation.
Journal of combinatorial chemistry , 2007 Nov-Dec: 1053-9
Epidemiology of schistosomiasis in the People's Republic of China, 2004.
Emerging infectious diseases , 2007 Oct: 1470-6
Human renal UOK130 tumor cells: a drug resistant cell line with highly selective over-expression of glutathione S-transferase-pi isozyme.
European journal of pharmacology , 2007 Jul 30: 61-7
Human renal UOK130 tumor cells: a drug resistant cell line with highly selective over-expression of glutathione S-transferase-pi isozyme.
European journal of pharmacology , 2007 Jul 30: 61-7
Isolation and enrichment of human genomic CpG islands by methylation-sensitive mirror orientation selection.
Analytical biochemistry , 2007 Jun 15: 153-64
Isolation and enrichment of human genomic CpG islands by methylation-sensitive mirror orientation selection.
Analytical biochemistry , 2007 Jun 15: 153-64
[Effectiveness of routinely used assays for the diagnosis of schistosomiasis japonica in the field]
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2007 Jun: 175-9
Polymyxin B antagonizing biological activity of lipopolysaccharide.
Chinese journal of traumatology = Zhonghua chuang shang za zhi / Chinese Medical Association , 2007 Jun: 180-3
Polymyxin B antagonizing biological activity of lipopolysaccharide.
Chinese journal of traumatology = Zhonghua chuang shang za zhi / Chinese Medical Association , 2007 Jun: 180-3
The newly identified CpG-N ODN208 protects mice from challenge with CpG-S ODN by decreasing TNF-alpha release.
International immunopharmacology , 2007 May: 646-55
[Observation on the change of anti-S. japonicum antibody level in population migrated from outside embankment to new town]
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2007 Apr 30: 146-9
[Evaluation on schistosomiasis control effect of the intervention measures adapted to the ecological environment changes in Jiang Han Plain due to establishment of the Three Gorges dam]
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2007 Apr 30: 114-9
[Study of lipopolysaccharide antagonizing effect of DPR-2 in vitro]
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2007 Apr: 104-7
Efficacy of interferon treatment for chronic hepatitis C predicted by feature subset selection and support vector machine.
Journal of medical systems , 2007 Apr: 117-23
Efficacy of interferon treatment for chronic hepatitis C predicted by feature subset selection and support vector machine.
Journal of medical systems , 2007 Apr: 117-23
Deacetylclivorine: a gender-selective metabolite of clivorine formed in female Sprague-Dawley rat liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals , 2007 Apr: 607-13
Differential distribution of glycine transporters in Müller cells and neurons in amphibian retinas.
Visual neuroscience , 2007 Mar-Apr: 157-68
Development of polyclonal antibodies for the detection of styrene oxide modified proteins.
Chemical research in toxicology , 2007 Feb: 316-21
[The methylation and mRNA expression of SLC5A8 and TMS1/ASC genes in human glioma]
Zhonghua yi xue za zhi , 2007 Jan 30: 292-7
[The methylation and mRNA expression of SLC5A8 and TMS1/ASC genes in human glioma]
Zhonghua yi xue za zhi , 2007 Jan 30: 292-7
Characterization of glycinergic synapses in vertebrate retinas.
Journal of biomedical science , 2007 Jan: 5-13
[Effect of adiponectin on nonalcoholic fatty liver disease]
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology , 2006 Dec: 952-4
Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma.
Neuroscience research , 2006 Dec: 450-8
Expression analyses of 27 DNA repair genes in astrocytoma by TaqMan low-density array.
Neuroscience letters , 2006 Dec 1: 112-7
Colorimetric diffusion-reflection imaging high-throughput analysis of organic or inorganic compounds.
Journal of combinatorial chemistry , 2006 Nov-Dec: 881-9
Support vector machine-based feature selection for classification of liver fibrosis grade in chronic hepatitis C.
Journal of medical systems , 2006 Oct: 389-94
Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells.
Toxicology , 2006 Sep 21: 99-106
The antimalarial artemisinin synergizes with antibiotics to protect against lethal live Escherichia coli challenge by decreasing proinflammatory cytokine release.
Antimicrobial agents and chemotherapy , 2006 Jul: 2420-7
Decreased intracellular TLR9 confers hyporesponsiveness of RAW264.7 cells to subsequent CpG ODN challenge.
International immunopharmacology , 2006 Jun: 935-46
Adsorption/desorption studies of NOx on well-mixed oxides derived from Co-Mg/Al Hydrotalcite-like compounds.
The journal of physical chemistry. B , 2006 Mar 9: 4291-300
Scanning scene tunnel for city traversing.
IEEE transactions on visualization and computer graphics , 2006 Mar-Apr: 155-67
Use of an artificial neural network to localize accessory pathways of Wolff-Parkinson-White syndrome with 12-lead electrocardiogram.
Medical informatics and the Internet in medicine , 2005 Dec: 277-86
Evaluation on the applied value of the dot immunogold filtration assay (DIGFA) for rapid detection of anti-Schistosoma japonicum antibody.
Acta tropica , 2005 Nov-Dec: 142-7
Surveillance of schistosomiasis in five provinces of China which have reached the national criteria for elimination of the disease.
Acta tropica , 2005 Nov-Dec: 276-81
An economic evaluation of the national schistosomiasis control programme in China from 1992 to 2000.
Acta tropica , 2005 Nov-Dec: 255-65
The public health significance and control of schistosomiasis in China--then and now.
Acta tropica , 2005 Nov-Dec: 97-105
[Study of the anti-endotoxin effect of beta-1, 2, 3, 4, 6-penta-O-galloyl-D-glucopyranose in vitro]
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2005 Aug: 282-4
A synthesized cationic tetradecapeptide from hornet venom kills bacteria and neutralizes lipopolysaccharide in vivo and in vitro.
Biochemical pharmacology , 2005 Jul 15: 209-19
[Experimental study on the antagonistic activity of cationic multi-peptide mastoparan-1 against lipopolysaccharide]
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2005 Jun: 189-92
The screening and isolation of an effective anti-endotoxin monomer from Radix Paeoniae Rubra using affinity biosensor technology.
International immunopharmacology , 2005 Jun: 1007-17
Mechanistic studies of inactivation of glutathione S-transferase Pi isozyme by a haloenol lactone derivative.
Medicinal chemistry (Shariqah (United Arab Emirates)) , 2005 Mar: 191-8
Nanoporous silica-supported nanometric palladium: synthesis, characterization, and catalytic deep oxidation of benzene.
Environmental science & technology , 2005 Mar 1: 1319-23
Schistosomiasis control in China: the impact of a 10-year World Bank Loan Project (1992-2001).
Bulletin of the World Health Organization , 2005 Jan: 43-8
[Effect of oxygen therapy for injury of intestinal mucosal barrier of rabbits in high altitude hemorrhagic shock.]
Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue , 2005 Jan: 32-5
Diagnosis of Helicobacter pylori infection and diseases associated with Helicobacter pylori by Helicobacter pylori outer membrane proteins.
World journal of gastroenterology : WJG , 2004 Dec 1: 3464-9
Detection of glutathione conjugates derived from 4-ipomeanol metabolism in bile of rats by liquid chromatography-tandem mass spectrometry.
Drug metabolism and disposition: the biological fate of chemicals , 2004 Dec: 1345-50
Cloning and sequence analysis of gene oipA encoding an outer membrane protein of human Helicobacter pylori.
World journal of gastroenterology : WJG , 2004 Nov 1: 3205-7
Lipopolysaccharide could be internalized into human peripheral blood mononuclear cells and elicit TNF-alpha release, but not via the pathway of toll-like receptor 4 on the cell surface.
Cellular & molecular immunology , 2004 Oct: 373-7
[Study on the risk factors of schistosomiasis transmission and control strategy in the Three Gorges Reservoir Areas]
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi , 2004 Jul: 559-63
Design, synthesis, and structure-activity relationships of haloenol lactones: site-directed and isozyme-selective glutathione S-transferase inhibitors.
Journal of medicinal chemistry , 2004 Jun 3: 3282-94
A synthetic peptide derived from bactericidal/permeability-increasing protein neutralizes endotoxin in vitro and in vivo.
International immunopharmacology , 2004 Apr: 527-37
[Study of biosensor technology on the detection of endotoxin-neutralizing materials]
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2004 Feb: 23-5
Chloroquine protects mice from challenge with CpG ODN and LPS by decreasing proinflammatory cytokine release.
International immunopharmacology , 2004 Feb: 223-34
Mechanism-based inactivation of cytochrome P450 3A4 by 4-ipomeanol.
Chemical research in toxicology , 2004 Feb: 150-7
[Construction, expression and antigenicity of bivalent vaccine candidate of human Helicobacter pylori]
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology , 2004 Jan: 62-6
Preparation and catalytic properties of ZrO2-Al2O3 composite oxide supported nickel catalysts for methane reforming with carbon dioxide.
Journal of environmental sciences (China) , 2004: 316-20
A sensitive method for the determination of the novel cholinesterase inhibitor ZT-1 and its active metabolite huperzine A in rat blood using liquid chromatography/tandem mass spectrometry.
Rapid communications in mass spectrometry : RCM , 2004: 651-6
Construction and characterization of bivalent vaccine candidate expressing HspA and M(r)18,000 OMP from Helicobacter pylori.
World journal of gastroenterology : WJG , 2003 Aug: 1756-61
[Construction, expression and antigenic study of bivalent vaccine candidate with 26,000 OMP and heat short protein A of human Helicobacter pylori]
Zhonghua yi xue za zhi , 2003 May 25: 862-7
[The expression and analysis of its activity of anti-bacterial peptide gloverin in COS-7 cells]
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2003 Apr: 86-8
[Schistosomiasis control in China: progress and challenges]
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases , 2003: 4-5
Relationship between lymphocyte apoptosis and endotoxin translocation after thermal injury in rats.
World journal of gastroenterology : WJG , 2002 Jun: 546-50
Studies of impact on physical fitness and working capacity of patients with advanced Schistosomiasis japonica in Susong County, Anhui Province.
Acta tropica , 2002 May: 247-52
Recent investigations of artemether, a novel agent for the prevention of schistosomiasis japonica, mansoni and haematobia.
Acta tropica , 2002 May: 175-81
Relationship between the transmission of schistosomiasis japonica and the construction of the Three Gorge Reservoir.
Acta tropica , 2002 May: 147-56
[The study on the role of modeling peptides derived from bactericidal/permeability increasing protein on the endotoxin neutralization]
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2002 Apr: 95-8
[An experimental study of the LPS release from gram-negative bacteria induced by antibiotics (Part two)]
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns , 2002 Apr: 92-4
[Rapid identification of Oncomelania hupensis snail habitat in the Poyang Lake region by Geographic Information System (GIS) and Remote Sensing (RS)]
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi , 2002 Apr: 99-101
A study of recombinant protective H.pylori antigens.
World journal of gastroenterology : WJG , 2002 Apr: 308-11

Presentations

Presentations TitleEventLocationDate
Haloenol Lactone: A Site-Directed Irreversible Inhibitor of Glutathione S-Transferase as a Modulator to Combat Drug Resistance in ChemotherapySchool of Pharmaceutical Engineering, Shenyang Pharmaceutical UniversityChinaNov. 1, 2009
Targeting Glutathione S-Transferase: A Strategy to Combat Chemotherapy ResistanceChinese Medicinal Chemistry SymposiumChinaNov. 1, 2009
Bioactivation and toxicity of natural products bisbenzylisoquinone alkaloids9th Chinese National Conference on Drug and Xenobiotic MetabolismChinaNov. 1, 2009
Bioactivation and pulmonary toxicity of bisbenzylisoquinone alkaloidsInstitute of Traditional Chinese Medicine, Shanghai University of Traditional MedicineShanghai, ChinaOct. 1, 2009
Targeting Glutathione S-Transferase: A Strategy to Combat Chemotherapy ResistanceSchool of Basic Medical Science, Wuhan UniversityChinaApril 1, 2009

Primary Office

Seattle Children's Research Institute
JMB - 9 - Developmental Therapeutics
1900 - 9th Ave
Seattle, WA 98101
206-884-1101

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