Prevalence and prognostic significance of KIT mutations in pediatric patients with core binding factor AML enrolled on serial pediatric cooperative trials for de novo AML.
, 2010 Mar 25: 2372-9
Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.
Cell stem cell
, 2010 Mar 5: 251-64
Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution.
, 2010 Feb: 232-6
Single-unit dominance after double-unit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit.
, 2010 Jan 28: 757-65
Hematopoietic stem cell function and survival depend on c-Myc and N-Myc activity.
Cell stem cell
, 2008 Dec 4: 611-24
E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors.
Journal of immunology (Baltimore, Md. : 1950)
, 2008 Nov 1: 5885-94
Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.
Genes & development
, 2008 Jun 15: 1677-89
Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival.
, 2008 Apr 15: 4338-47
Notch target Hes5 ensures appropriate Notch induced T- versus B-cell choices in the thymus.
, 2008 Mar 1: 2615-20
Phosphorylated ITIMs enable ubiquitylation of an inhibitory cell surface receptor.
Traffic (Copenhagen, Denmark)
, 2008 Feb: 267-79
ITIM-dependent endocytosis of CD33-related Siglecs: role of intracellular domain, tyrosine phosphorylation, and the tyrosine phosphatases, Shp1 and Shp2.
Journal of leukocyte biology
, 2008 Jan: 200-11
Clinical strategies to enhance posttransplant immune reconstitution.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
, 2008 Jan: 94-9
The interaction of the Wnt and Notch pathways modulates natural killer versus T cell differentiation.
Stem cells (Dayton, Ohio)
, 2007 Oct: 2488-97
CD33 expression and P-glycoprotein-mediated drug efflux inversely correlate and predict clinical outcome in patients with acute myeloid leukemia treated with gemtuzumab ozogamicin monotherapy.
, 2007 May 15: 4168-70
Enhanced T-cell reconstitution by hematopoietic progenitors expanded ex vivo using the Notch ligand Delta1.
, 2007 Apr 15: 3579-87
FLT3 internal tandem duplication in CD34+/CD33- precursors predicts poor outcome in acute myeloid leukemia.
, 2006 Oct 15: 2764-9
131I-anti-CD45 antibody plus busulfan and cyclophosphamide before allogeneic hematopoietic cell transplantation for treatment of acute myeloid leukemia in first remission.
, 2006 Mar 1: 2184-91
Delineation of the minimal commonly deleted segment and identification of candidate tumor-suppressor genes in del(9q) acute myeloid leukemia.
Genes, chromosomes & cancer
, 2005 Nov: 279-91
Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells.
, 2005 Oct 15: 2693-9
Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence.
, 2005 Oct 1: 1442-52
Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells.
The Journal of experimental medicine
, 2005 May 2: 1361-6
Influence of CD33 expression levels and ITIM-dependent internalization on gemtuzumab ozogamicin-induced cytotoxicity.
, 2005 Feb 1: 1295-302
The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas.
, 2004 Nov 1: 7794-800
The peripheral benzodiazepine receptor ligand PK11195 overcomes different resistance mechanisms to sensitize AML cells to gemtuzumab ozogamicin.
, 2004 Jun 1: 4276-84
Establishment of a pluripotent preleukaemic stem cell line by expression of the AML1-ETO fusion protein in Notch1-immortalized HSCN1cl10 cells.
British journal of haematology
, 2004 May: 353-7
Progenitor cell involvement is predictive of response to induction chemotherapy in paediatric acute myeloid leukaemia.
British journal of haematology
, 2003 Nov: 431-5
Conditionally cleavable radioimmunoconjugates: a novel approach for the release of radioisotopes from radioimmunoconjugates.
, 2003 Sep-Oct: 927-33
Multidrug resistance protein attenuates gemtuzumab ozogamicin-induced cytotoxicity in acute myeloid leukemia cells.
, 2003 Aug 15: 1466-73
Activating mutations of RTK/ras signal transduction pathway in pediatric acute myeloid leukemia.
, 2003 Aug 15: 1474-9
Immunophenotypic evidence of leukemia after induction therapy predicts relapse: results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia.
, 2003 May 1: 3398-406
Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability.
, 2003 Mar 1: 1784-9
Delta-1 enhances marrow and thymus repopulating ability of human CD34(+)CD38(-) cord blood cells.
The Journal of clinical investigation
, 2002 Oct: 1165-74
High-dose chemo-radioimmunotherapy with autologous stem cell support for relapsed mantle cell lymphoma.
, 2002 May 1: 3158-62
CD33 as a target for selective ablation of acute myeloid leukemia.
, 2002 Mar: S9-11
Antibody-directed therapies for hematological malignancies.
Trends in molecular medicine
, 2002 Feb: 69-76