Profile

Chappie Conrad, MD

Chappie Conrad, MD

Orthopedics, Hematology-Oncology, Vascular Anomalies

On staff since December 1986

Children's Title: Director, Department of Orthopedics; Chief, Orthopedic Oncology; Chief, Bone Tumor

Research Center: Center for Clinical and Translational Research

"I am an academic surgeon with a clinical and research practice dedicated to all aspects of orthopedic oncology. As the director of the multi-disciplinary sarcoma services at the University of Washington, Seattle Cancer Care Aliance, and Seattle Children's Hospital, I am committed to fostering research in all areas relating to musculo-skeletal oncology."

Dr. Conrad is a professor of orthopaedic surgery in the Department of Orthopaedics and Sports Medicine at the University of Washington Medical Center and Seattle Children’s Hospital. He joined the faculty in 1986 after completing his training at the Hospital of Special Surgery in New York City. He also completed a musculoskeletal tumor fellowship with Dr. William Enneking and a pediatric orthopaedic fellowship with Dr. Mercer Rang. When he joined the Department of Orthopaedics, he instituted their Division of Musculoskeletal Oncology and Transplantation. In addition to those duties, he directs the Division of Orthopaedic Surgery at the University of Washington and serves as the Medical Director at the Northwest Tissue Center, a regional nonprofit tissue center in Seattle. Dr. Conrad’s research projects include multiple clinical studies in pediatric and adult tumors with a special interest in pediatric limb-sparing procedures, benign pediatric tumors, and soft-tissue sarcomas in adults.

His research interests include the metabolic imaging of sarcomas with the use of CT scans, clinical and biologic descriptions of hereditary multiple exostoses, and the biologic responses associated with musculoskeletal transplantation.

Recommendations

  • Cody Ritzville, WA 04.26.14

    Dr. Conrad was the doctor who worked with me in relation to bone damage I suffered during cancer when I was a child. This man allowed me to walk for the rest of my life and I love him like a God Father. He always diffused the tense mood around my appointments, and while I was too young to understand just how much he did, as I have grown older I have cursed God and Country but Never Conrad. My parents feel even stronger about this than I do, how else do you react to the man who saves your sons life and leg? I know I was never an Ideal patient, and I know I always said medicine and doctors were evil, even though it was jokingly. I want Dr Conrad and his entire team, and Dr Hawkins and his team, to know I cant just thank them, but will love them like family till the day I die. You too Susan!

  • Joseph SEATTLE, wASHINGTON 03.26.14

    Dr Conrad is like no other....he was sent from the heavens to bring those of us on earth a new chance at life. I love his professionalism and kind/complete way of patient treatment. In June 2004 Dr. Conrad and staff performed their magic on my left leg which I had accidently blown off with a fireworks cannon. All of the doctors I had seen prior said it was over....time to amputate the entire leg. I was broken....Then by the grace of god found Dr Conrad. My leg has now provided me 10+ years of complete satisfaction and more important, a meaningful life. This man is a wizard in his field and may god bless him for the talent he brings to medicine. Thank You Dr Conrad, Sincerely, Joe Dion

  • Marci England, UK 03.04.13

    There is no better doctor out there. He treated me for a very long, and difficult year. Always looked forward to seeing him and he dealt very well with my attitude. My knee replacement has lasted over 15 years and doctors here in England are very impressed. Now a wife and mother to a daughter and twin boys all thanks to him and the other fabulous doctors at children's hospital.

  • Kendra Rochester, WA 05.17.12

    I saw Dr. Conrad in 1995 for a tumor in my femur. I had two surgeries under his care. I agree completely with these recommendations. He is the best. He was caring and so kind to me and my family. I will never forget what he has done for me! I wish I could see him more often. I think of him with such gratitude all of the time. I was told before seeing Dr. Conrad that I would probably loss my leg. Because of him my cancer was removed, I kept my leg and live a wonderful life now. I am a wife and mom, I am able to be physically active. He is SO highly recommended by me and all of my family. Thanks, Dr, Conrad. You are the best.

  • Margo Saratoga, CA 09.17.11

    I had surgery from Dr. Conrad September 16, 2005. I was two weeks into my freshman year of college age 18. I didn't know what exactly was wrong with my femur prior to going to college in Washington; I attended Pacific Lutheran University. When I finally got to see Dr. Conrad at Seattle Children's Hospital, he was caring and considerate of not just how I was taking the information but also my mother who was with me. From my first appointment to surgery was only 4 days apart but that was what was needed with my condition. He is a great surgeon and he has my full respect. After my surgery, when he came into my room, he was nice and respectful and asked my mom how she was. Every year, on the anniversary of my surgery on my femur I think of him and wish that he could see how I was doing. Thank you Dr. Conrad for everything and I recommend that you go to him if you need surgery.

  • Mairissa Butte, Montana 06.30.11

    I first met Chappie 4 years ago, shortly after I turned 17. I was facing a possibly cancer diagnosis and was absolutely terrified. I said goodbye to my parents and I was taken, sobbing, into the operating room. Chappie was there waiting for me and held my hand until I fell asleep. At that moment I knew that I was going to be okay. Unfortunately, I was diagnosed with cancer that day and had been dealing with it on and off since then. Chappie is THE reason that I am here today. I have been told several times that there was nothing more that could be done for me, but Chappie has come to the rescue every time. He cares just as much about me and the things going on in my life as he does about me health. I owe my life to him.

  • Amanda Yakima, Washington 06.25.11

    I was diagnosed with Osteosarcoma February 25th, 2010 at the age of 16. I live in Yakima, Washington but I was sent to Seattle for my chemo therapy treatment and my surgery to remove the tumor in my knee as well as my entire femur. Chappi did my surgery and I went in thinking I would come out with no leg. He had told me to be prepared for it because it was very possible. To my surprise I woke up with a beautiful leg! Chappi is just so compassionate about the work he does. He not like some ordinary doctors and surgeons. He cares for the welfare of others. He gets down on a personal level with others. I care alot about this man and I hope to take his place as a surgeon at Seattle Children's Hospital. He saved my leg and my life! I love that man. People at Children's say I have his heart. Thanks Chappi!

  • Summer port angeles WA 05.09.11

    I had surgery done by Dr. Conrad, in March 2010 and he did a really great job. He was friendly, supportive and I have healed up very well. I recommend him.

  • Kelly Kirkland Washington 03.22.11

    I have been seeing Doctor Conrad for the last 19 years, since I was a few months old. I have had two major surgeries done by him, and seen him various times for my multiple hereditary exostosis. He is always so kind, knowledgeable, intelligent, and trustworthy. I feel so safe under his expertise and care! I wouldn't see any other doctor!

Overview

Board Certification(s)

Orthopedic Surgery

Medical/Professional School

University of Virginia School of Medicine, Charlottesville

Fellowship

Orthopedic Surgery, University of Florida College of Medicine, Gainesville
Orthopedic Surgery, Hospital for Sick Children, Toronto

Clinical Interests

Bone Tumors General Orthopedics

Research Focus Area

Translational Research, Therapeutic Trials

Awards and Honors

Award Name Award Description Awarded By Award Date
U.S. News Top Doctor U.S. News and World Report 2012
Seattle Magazine Top Doctor - 2012 Seattle Magazine Top Doctor - 2012 Seattle Magazine 2012
"Guide to America's Top Pediatricians" Consumer's Research Council of America 2009
Top Doctor – Seattle Magazine Seattle Magazine 2006
Cancer – Top Doctor Castle Connolly LTD 2006
Most Valuable Poster/Presentation Award 8th Annual International Symposium on Limb Salvage, Florence, Italy 2005
Who’s Who – McMaster McMaster 2005
Clinical Teaching Award University of Washington/MEDEX Northwest Program 1999
Orthopaedics Faculty, Resident Teaching Award University of Washington 1991

Publications

  • Hingorani P, Seidel K, Krailo M, Mascarenhas L, Meyers P, Marina N, Conrad EU, Hawkins DS
    Body mass index (BMI) at diagnosis is associated with surgical wound complications in patients with localized osteosarcoma: a report from the Children's Oncology Group.
    Pediatric blood & cancer , 2011 Dec. 1 : 939-42
  • Eary JF, Conrad EU
    Imaging in Sarcoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine , 2011 Nov. 3
  • Scharschmidt TJ, Lindsey JD, Becker PS, Conrad EU
    Multiple myeloma: diagnosis and orthopaedic implications.
    The Journal of the American Academy of Orthopaedic Surgeons , 2011 July : 410-9
  • Eary JF, Link JM, Muzi M, Conrad EU, Mankoff DA, White JK, Krohn KA
    Multiagent PET for risk characterization in sarcoma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine , 2011 Apr, : 541-6
  • Chappie Conrad, MD
    Multiagent PET for Risk Characterization in Sarcoma.
    J Nucl Med , 2011 : 52541-546
  • Chappie Conrad, MD
    Eary JF, Hawkins DS, Rodler ET, Conrad EU 3rd
    Am J Nucl Med Mol Imaging , 2011 : 1(1)47-53
  • Chappie Conrad, MD
    Torsional stability of uncemented femoral stems in oncologic reconstructions
    Ortho , 2011 Jan. : 34(2)96
  • Scharschmidt T, Cohen A, Thomas N, Ching R, Conrad E
    Torsional stability of uncemented femoral stems in oncologic reconstructions.
    Orthopedics , 2011 Jan. 1 : 96
  • Ghatan A, Scharschmidt T, Conrad E
    Extreme enchondromatosis: a report of two cases and review of the literature.
    The Journal of bone and joint surgery. American volume , 2010 Oct. 6 : 2336-43
  • Demetri GD, Antonia S, Benjamin RS, Bui MM, Casper ES, Conrad EU 3rd, DeLaney TF, Ganjoo KN, Heslin MJ, Hutchinson RJ, Kane JM 3rd, Letson GD, McGarry SV, O'Donnell RJ, Paz IB, Pfeifer JD, Pollock RE, Randall RL, Riedel RF, Schupak KD, Schwartz HS, Thornton K, von Mehren M, Wayne J, National Comprehensive Cancer Network Soft Tissue Sarcoma Panel
    Soft tissue sarcoma.
    Journal of the National Comprehensive Cancer Network : JNCCN , 2010 June : 630-74
  • Biermann JS, Adkins DR, Benjamin RS, Brigman B, Chow W, Conrad EU 3rd, Frassica DA, Frassica FJ, George S, Hande KR, Hornicek FJ, Letson GD, Mayerson J, McGarry SV, McGrath B, Morris CD, O'Donnell RJ, Randall RL, Santana VM, Satcher RL, Siegel HJ, Somaiah N, Yasko AW, National Comprehensive Cancer Network Bone Cancer Panel
    Bone cancer.
    Journal of the National Comprehensive Cancer Network : JNCCN , 2010 June : 688-712
  • Schmale GA, Hawkins DS, Rutledge J, Conrad EU
    Malignant progression in two children with multiple osteochondromas.
    Sarcoma , 2010 : 417105
  • Chappie Conrad, MD
    69. Malignant Progression in Two Children with Multiple Osteochondromas
    Sarcoma Volume 2010 , 2010
  • Chou AJ, Kleinerman ES, Krailo MD, Chen Z, Betcher DL, Healey JH, Conrad EU 3rd, Nieder ML, Weiner MA, Wells RJ, Womer RB, Meyers PA, Children's Oncology Group
    Addition of muramyl tripeptide to chemotherapy for patients with newly diagnosed metastatic osteosarcoma: a report from the Children's Oncology Group.
    Cancer , 2009 Nov. 15 : 5339-48
  • Zimel MN, Cizik AM, Rapp TB, Weisstein JS, Conrad EU 3rd
    Megaprosthesis versus Condyle-sparing intercalary allograft: distal femoral sarcoma.
    Clinical orthopaedics and related research , 2009 Nov. : 2813-24
  • Hawkins DS, Conrad EU 3rd, Butrynski JE, Schuetze SM, Eary JF
    [F-18]-fluorodeoxy-D-glucose-positron emission tomography response is associated with outcome for extremity osteosarcoma in children and young adults.
    Cancer , 2009 Aug. 1 : 3519-25
  • Punt SE, Eary JF, O'Sullivan J, Conrad EU
    Fluorodeoxyglucose positron emission tomography in leiomyosarcoma: imaging characteristics.
    Nuclear medicine communications , 2009 July : 546-9
  • Lisle JW, Eary JF, O'Sullivan J, Conrad EU
    Risk assessment based on FDG-PET imaging in patients with synovial sarcoma.
    Clinical orthopaedics and related research , 2009 June : 1605-11
  • Eary JF, O'Sullivan F, O'Sullivan J, Conrad EU
    Spatial heterogeneity in sarcoma 18F-FDG uptake as a predictor of patient outcome.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine , 2008 Dec. : 1973-9
  • Demetri GD, Baker LH, Benjamin RS, Casper ES, Conrad EU 3rd, D'Amato GZ, DeLaney TF, Ettinger DS, Heck R Jr, Heslin MJ, Hutchinson RJ, Jacobs CD, Kiel K, Kraybill WG, Letson GD, O'Donnell RJ, Paz IB, Pfeifer J, Pollock RE, Randall RL, Sasson AR, Schupak KD, Tyler DS, von Mehren M, Wayne J, National Comprehensive Cancer Network
    Soft tissue sarcoma.
    Journal of the National Comprehensive Cancer Network : JNCCN , 2007 Apr, : 364-99
  • Biermann JS, Adkins D, Benjamin R, Brigman B, Chow W, Conrad EU 3rd, Frassica D, Frassica FJ, George S, Healey JH, Heck R Jr, Letson GD, Mayerson J, McGarry SV, O'Donnell RJ, Patt J, Randall RL, Santana V, Satcher RL, Schmidt RG, Siegel HJ, Wong MK, Yasko AW, National Comprehensive Cancer Network
    Bone cancer.
    Journal of the National Comprehensive Cancer Network : JNCCN , 2007 Apr, : 420-37
  • Eary JF, Conrad EU
    PET imaging: update on sarcomas.
    Oncology (Williston Park, N.Y.) , 2007 Feb. : 249-52
  • Brenner W, Eary JF, Hwang W, Vernon C, Conrad EU
    Risk assessment in liposarcoma patients based on FDG PET imaging.
    European journal of nuclear medicine and molecular imaging , 2006 Nov. : 1290-5
  • Morgan HD, Cizik AM, Leopold SS, Hawkins DS, Conrad EU 3rd
    Survival of tumor megaprostheses replacements about the knee.
    Clinical orthopaedics and related research , 2006 Sept. : 39-45
  • Hawkins DS, Schuetze SM, Butrynski JE, Rajendran JG, Vernon CB, Conrad EU 3rd, Eary JF
    [18F]Fluorodeoxyglucose positron emission tomography predicts outcome for Ewing sarcoma family of tumors.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2005 Dec. 1 : 8828-34
  • Chang A, Schuetze SM, Conrad EU 3rd, Swisshelm KL, Norwood TH, Rubin BP
    So-called "inflammatory leiomyosarcoma'': a series of 3 cases providing additional insights into a rare entity.
    International journal of surgical pathology , 2005 Apr, : 185-95
  • Randall RL, Bruckner J, Lloyd C, Pohlman TH, Conrad EU 3rd
    Sacral resection and reconstruction for tumors and tumor-like conditions.
    Orthopedics , 2005 Mar. : 307-13
  • Biermann JS, Baker LH, Benjamin R, Brigman B, Chow W, Conrad EU 3rd, Frassica D, Frassica FJ, George S, Healey JH, Heck R, Letson GD, Mayerson J, Neff J, O'Donnell RJ, Randall RL, Santana V, Satcher RL, Schmidt RG, Siegel HJ, Wong MK, Yasko AW, National Comprehensive Cancer Network
    Bone cancer clinical practice guidelines.
    Journal of the National Comprehensive Cancer Network : JNCCN , 2005 Mar. : 124-40
  • Demetri GD, Baker LH, Beech D, Benjamin R, Casper ES, Conrad EU 3rd, DeLaney TF, Ettinger DS, Heslin MJ, Hutchinson RJ, Kiel K, Kraybill WG, Letson GD, Neff J, O'Donnell RJ, Paz IB, Pollock RE, Randall RL, Schupak KD, Tyler DS, von Mehren M, Wayne J, National Comprehensive Cancer Network
    Soft tissue sarcoma clinical practice guidelines in oncology.
    Journal of the National Comprehensive Cancer Network : JNCCN , 2005 Mar. : 158-94
  • Wunder JS, Gokgoz N, Parkes R, Bull SB, Eskandarian S, Davis AM, Beauchamp CP, Conrad EU, Grimer RJ, Healey JH, Malkin D, Mangham DC, Rock MJ, Bell RS, Andrulis IL
    TP53 mutations and outcome in osteosarcoma: a prospective, multicenter study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2005 Mar. 1 : 1483-90
  • Bassett MD, Schuetze SM, Disteche C, Norwood TH, Swisshelm K, Chen X, Bruckner J, Conrad EU 3rd, Rubin BP
    Deep-seated, well differentiated lipomatous tumors of the chest wall and extremities: the role of cytogenetics in classification and prognostication.
    Cancer , 2005 Jan. 15 : 409-16
  • Brenner W, Vernon C, Muzi M, Mankoff DA, Link JM, Conrad EU, Eary JF
    Comparison of different quantitative approaches to 18F-fluoride PET scans.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine , 2004 Sept. : 1493-500
  • Brenner W, Vernon C, Conrad EU, Eary JF
    Assessment of the metabolic activity of bone grafts with (18)F-fluoride PET.
    European journal of nuclear medicine and molecular imaging , 2004 Sept. : 1291-8
  • Chansky HA, Barahmand-Pour F, Mei Q, Kahn-Farooqi W, Zielinska-Kwiatkowska A, Blackburn M, Chansky K, Conrad EU 3rd, Bruckner JD, Greenlee TK, Yang L
    Targeting of EWS/FLI-1 by RNA interference attenuates the tumor phenotype of Ewing's sarcoma cells in vitro.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society , 2004 July : 910-7
  • Rajendran JG, Mankoff DA, O'Sullivan F, Peterson LM, Schwartz DL, Conrad EU, Spence AM, Muzi M, Farwell DG, Krohn KA
    Hypoxia and glucose metabolism in malignant tumors: evaluation by [18F]fluoromisonidazole and [18F]fluorodeoxyglucose positron emission tomography imaging.
    Clinical cancer research : an official journal of the American Association for Cancer Research , 2004 Apr, 1 : 2245-52
  • Beaulieu S, Rubin B, Djang D, Conrad E, Turcotte E, Eary JF
    Positron emission tomography of schwannomas: emphasizing its potential in preoperative planning.
    AJR. American journal of roentgenology , 2004 Apr, : 971-4
  • Brenner W, Conrad EU, Eary JF
    FDG PET imaging for grading and prediction of outcome in chondrosarcoma patients.
    European journal of nuclear medicine and molecular imaging , 2004 Feb. : 189-95
  • Conrad EU 3rd, Morgan HD, Vernon C, Schuetze SM, Eary JF
    Fluorodeoxyglucose positron emission tomography scanning: basic principles and imaging of adult soft-tissue sarcomas.
    The Journal of bone and joint surgery. American volume , 2004 : 98-104
  • Newkirk L, Vater Y, Oxorn D, Mulligan M, Conrad E
    Intraoperative TEE for the management of pulmonary tumour embolism during chondroblastic osteosarcoma resection.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie , 2003 Nov. : 886-90
  • Van Boerum DH, Randall RL, Mohr RA, Conrad EU, Bachus KN
    Rotational stability of a modified step-cut for use in intercalary allografts.
    The Journal of bone and joint surgery. American volume , 2003 June : 1073-8
  • Vernon CB, Eary JF, Rubin BP, Conrad EU 3rd, Schuetze S
    FDG PET imaging guided re-evaluation of histopathologic response in a patient with high-grade sarcoma.
    Skeletal radiology , 2003 Mar. : 139-42
  • Rubin BP, Schuetze SM, Eary JF, Norwood TH, Mirza S, Conrad EU, Bruckner JD
    Molecular targeting of platelet-derived growth factor B by imatinib mesylate in a patient with metastatic dermatofibrosarcoma protuberans.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology , 2002 Sept. 1 : 3586-91
  • Eary JF, O'Sullivan F, Powitan Y, Chandhury KR, Vernon C, Bruckner JD, Conrad EU
    Sarcoma tumor FDG uptake measured by PET and patient outcome: a retrospective analysis.
    European journal of nuclear medicine and molecular imaging , 2002 Sept. : 1149-54
  • Rapp TB, Yang L, Conrad EU 3rd, Mandahl N, Chansky HA
    RNA splicing mediated by YB-1 is inhibited by TLS/CHOP in human myxoid liposarcoma cells.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society , 2002 July : 723-9
  • Hawkins DS, Rajendran JG, Conrad EU 3rd, Bruckner JD, Eary JF
    Evaluation of chemotherapy response in pediatric bone sarcomas by [F-18]-fluorodeoxy-D-glucose positron emission tomography.
    Cancer , 2002 June 15 : 3277-84
  • Schwartz DL, Einck J, Hunt K, Bruckner J, Conrad E, Koh WJ, Laramore GE
    The effect of delayed postoperative irradiation on local control of soft tissue sarcomas of the extremity and torso.
    International journal of radiation oncology, biology, physics , 2002 Apr, 1 : 1352-9
  • Csönge L, Bravo D, Newman-Gage H, Rigley T, Conrad EU, Bakay A, Strong DM, Pellet S
    Banking of osteochondral allografts. Part I. Viability assays adapted for osteochondrol and cartilage studies.
    Cell and tissue banking , 2002 : 151-9
  • Csönge L, Bravo D, Newman-Gage H, Rigley T, Conrad EU, Bakay A, Strong DM, Pellet S
    Banking of osteochondral allografts, Part II. Preservation of Chondrocyte Viability During Long-Term Storage.
    Cell and tissue banking , 2002 : 161-8
  • Eary JF, Conrad EU
    Positron Emission Tomography in Grading Soft Tissue Sarcomas.
    Seminars in musculoskeletal radiology , 1999 : 135-138

Research Funding

Grant Title Grantor Amount Award Date
Mechanisms of Resistance in Sarcomas NIH $402,502.00 Jan. 1, 2009
Bone Tumor Research Bone and Joint Research Funds $75,000.00 Jan. 1, 2009
Staheli Endowed Chair at Seattle Children's Hospital and Regional Medical Center unknown $2,100,000.00 Jan. 1, 2009
unknown HowMedica/Stryker $109,407.00 Jan. 1, 2009
Sarcoma Research North West Tissue Center $78,361.00 Jan. 1, 2009
PET and Sarcoma: A Clinical Trial NIH $1,250,000.00 Jan. 1, 2000
Followup of Ewing’s Sarcoma 6. Margo Johnsen Endowment for Bone Tumor Research $630,000.00 Jan. 1, 1989