Profile

Anita E. Beck, MD, PhD

Anita E. Beck, MD, PhD

Genetics

On staff since March 2010

Research Center: Center for Clinical and Translational Research

"Compassionate care involves including the family as part of the team. I enjoy applying cutting-edge research findings to address human concerns."

  • Award Name Award Description Awarded By Award Date
    Seattle Met magazine "Top Doctor" 2012
    National Institutes of Health (NIH)/ National Institute of Child Health and Development (NICHD) 5-year Mentored Patient-Oriented Research Career Development Award (K23): “Identifying the Genetic and Molecular Basis of Clubfoot” NIH/NICHD Jan. 1, 2009
    Scholarship (tuition and board) "Genetic Analysis of Complex Human Diseases" Course Duke University, Durham NC 2004
    Fellowship award NIGMS/NIH grant for "Postdoctoral Training in Medical Genetics" Stanford University 2003 - 2005
    • Racca AW, Klaiman JM, Pioner JM, Cheng Y, Beck AE, Moussavi-Harami F, Bamshad MJ, Regnier M
      Contractile properties of developing human fetal cardiac muscle.
      26460603 The Journal of physiology , 2016 Jan. 15 : 594(2)437-52 PMCID: PMC4713728
    • Racca AW, Klaiman JM, Pioner JM, Cheng Y, Beck AE, Moussavi-Harami F, Bamshad MJ, Regnier M
      Contractile properties of developing human fetal cardiac muscle.
      26460603 The Journal of physiology , 2016 Jan. 15 : 594(2)437-52 PMCID: PMC4713728
    • Racca AW, Beck AE, McMillin MJ, Korte FS, Bamshad MJ, Regnier M
      The embryonic myosin R672C mutation that underlies Freeman-Sheldon syndrome impairs cross-bridge detachment and cycling in adult skeletal muscle.
      25740846 Human molecular genetics , 2015 June 15 : 24(12)3348-58 PMCID: PMC4481580
    • Chong JX, Burrage LC, Beck AE, Marvin CT, McMillin MJ, Shively KM, Harrell TM, Buckingham KJ, Bacino CA, Jain M, Alanay Y, Berry SA, Carey JC, Gibbs RA, Lee BH, Krakow D, Shendure J, Nickerson DA, University of Washington Center for Mendelian Genomics., Bamshad MJ
      Autosomal-Dominant Multiple Pterygium Syndrome Is Caused by Mutations in MYH3.
      25957469 American journal of human genetics , 2015 May 7 : 96(5)841-9 PMCID: PMC4570285
    • Delgado F, Tabor HK, Chow PM, Conta JH, Feldman KW, Tsuchiya KD, Beck AE
      Single-nucleotide polymorphism arrays and unexpected consanguinity: considerations for clinicians when returning results to families.
      25232848 Genetics in medicine : official journal of the American College of Medical Genetics , 2015 May : 17(5)400-4 PMCID: PMC4404161
    • Chong JX, McMillin MJ, Shively KM, Beck AE, Marvin CT, Armenteros JR, Buckingham KJ, Nkinsi NT, Boyle EA, Berry MN, Bocian M, Foulds N, Uzielli ML, Haldeman-Englert C, Hennekam RC, Kaplan P, Kline AD, Mercer CL, Nowaczyk MJ, Klein Wassink-Ruiter JS, McPherson EW, Moreno RA, Scheuerle AE, Shashi V, Stevens CA, Carey JC, Monteil A, Lory P, Tabor HK, Smith JD, Shendure J, Nickerson DA, University of Washington Center for Mendelian Genomics., Bamshad MJ
      De novo mutations in NALCN cause a syndrome characterized by congenital contractures of the limbs and face, hypotonia, and developmental delay.
      25683120 American journal of human genetics , 2015 Mar. 5 : 96(3)462-73 PMCID: PMC4375444
    • Chen LP, Beck AE, Tsuchiya KD, Chow PM, Mirzaa GM, Wiester RT, Feldman KW
      Institutional protocol to manage consanguinity detected by genetic testing in pregnancy in a minor.
      25687148 Pediatrics , 2015 Mar. : 135(3)e736-9 PMCID: PMC4338324
    • Salehi P, Leavitt A, Beck AE, Chen ML, Roth CL
      Obesity management in Prader-Willi syndrome.
      25962207 Pediatric endocrinology reviews : PER , 2015 Mar. : 12(3)297-307
    • Chen LP, Beck AE, Tsuchiya KD, Chow PM, Mirzaa GM, Wiester RT, Feldman KW
      Institutional protocol to manage consanguinity detected by genetic testing in pregnancy in a minor.
      25687148 Pediatrics , 2015 Mar. : 135(3)e736-9 PMCID: PMC4338324
    • Beck AE, McMillin MJ, Gildersleeve HI, Shively KM, Tang A, Bamshad MJ
      Genotype-phenotype relationships in Freeman-Sheldon syndrome.
      25256237 American journal of medical genetics. Part A , 2014 Nov. : 164A(11)2808-13
    • McMillin MJ, Beck AE, Chong JX, Shively KM, Buckingham KJ, Gildersleeve HI, Aracena MI, Aylsworth AS, Bitoun P, Carey JC, Clericuzio CL, Crow YJ, Curry CJ, Devriendt K, Everman DB, Fryer A, Gibson K, Giovannucci Uzielli ML, Graham JM Jr, Hall JG, Hecht JT, Heidenreich RA, Hurst JA, Irani S, Krapels IP, Leroy JG, Mowat D, Plant GT, Robertson SP, Schorry EK, Scott RH, Seaver LH, Sherr E, Splitt M, Stewart H, Stumpel C, Temel SG, Weaver DD, Whiteford M, Williams MS, Tabor HK, Smith JD, Shendure J, Nickerson DA, University of Washington Center for Mendelian Genomics., Bamshad MJ
      Mutations in PIEZO2 cause Gordon syndrome, Marden-Walker syndrome, and distal arthrogryposis type 5.
      24726473 American journal of human genetics , 2014 May 1 : 94(5)734-44 PMCID: PMC4067551
    • Racca AW, Beck AE, Rao VS, Flint GV, Lundy SD, Born DE, Bamshad MJ, Regnier M
      Contractility and kinetics of human fetal and human adult skeletal muscle.
      23629510 The Journal of physiology , 2013 June 15 : 591(12)3049-61 PMCID: PMC3832119
    • Marneros AG, Beck AE, Turner EH, McMillin MJ, Edwards MJ, Field M, de Macena Sobreira NL, Perez AB, Fortes JA, Lampe AK, Giovannucci Uzielli ML, Gordon CT, Plessis G, Le Merrer M, Amiel J, Reichenberger E, Shively KM, Cerrato F, Labow BI, Tabor HK, Smith JD, Shendure J, Nickerson DA, Bamshad MJ, University of Washington Center for Mendelian Genomics.
      Mutations in KCTD1 cause scalp-ear-nipple syndrome.
      23541344 American journal of human genetics , 2013 Apr, 4 : 92(4)621-6 PMCID: PMC3617379
    • Beck AE, McMillin MJ, Gildersleeve HI, Kezele PR, Shively KM, Carey JC, Regnier M, Bamshad MJ
      Spectrum of mutations that cause distal arthrogryposis types 1 and 2B.
      23401156 American journal of medical genetics. Part A , 2013 Mar. : 161A(3)550-5 PMCID: PMC3581718
    • McMillin MJ, Below JE, Shively KM, Beck AE, Gildersleeve HI, Pinner J, Gogola GR, Hecht JT, Grange DK, Harris DJ, Earl DL, Jagadeesh S, Mehta SG, Robertson SP, Swanson JM, Faustman EM, Mefford HC, Shendure J, Nickerson DA, Bamshad MJ, University of Washington Center for Mendelian Genomics
      Mutations in ECEL1 cause distal arthrogryposis type 5D.
      23261301 American journal of human genetics , 2013 Jan. 10 : 92(1)150-6 PMCID: PMC3542461
    • McMillin MJ, Below JE, Shively KM, Beck AE, Gildersleeve HI, Pinner J, Gogola GR, Hecht JT, Grange DK, Harris DJ, Earl DL, Jagadeesh S, Mehta SG, Robertson SP, Swanson JM, Faustman EM, Mefford HC, Shendure J, Nickerson DA, Bamshad MJ, University of Washington Center for Mendelian Genomics.
      Mutations in ECEL1 cause distal arthrogryposis type 5D.
      23261301 American journal of human genetics , 2013 Jan. 10 : 92(1)150-6 PMCID: PMC3542461
    • Weymouth KS, Blanton SH, Bamshad MJ, Beck AE, Alvarez C, Richards S, Gurnett CA, Dobbs MB, Barnes D, Mitchell LE, Hecht JT
      Variants in genes that encode muscle contractile proteins influence risk for isolated clubfoot.
      21834041 American journal of medical genetics. Part A , 2011 Sept. : 2170-9 PMCID: PMC3158831
    • Weymouth KS, Blanton SH, Bamshad MJ, Beck AE, Alvarez C, Richards S, Gurnett CA, Dobbs MB, Barnes D, Mitchell LE, Hecht JT
      Variants in genes that encode muscle contractile proteins influence risk for isolated clubfoot.
      21834041 American journal of medical genetics. Part A , 2011 Sept. : 155A(9)2170-9 PMCID: PMC3158831
    • Hannibal MC, Buckingham KJ, Ng SB, Ming JE, Beck AE, McMillin MJ, Gildersleeve HI, Bigham AW, Tabor HK, Mefford HC, Cook J, Yoshiura K, Matsumoto T, Matsumoto N, Miyake N, Tonoki H, Naritomi K, Kaname T, Nagai T, Ohashi H, Kurosawa K, Hou JW, Ohta T, Liang D, Sudo A, Morris CA, Banka S, Black GC, Clayton-Smith J, Nickerson DA, Zackai EH, Shaikh TH, Donnai D, Niikawa N, Shendure J, Bamshad MJ
      Spectrum of MLL2 (ALR) mutations in 110 cases of Kabuki syndrome.
      21671394 American journal of medical genetics. Part A , 2011 July : 155A(7)1511-6 PMCID: PMC3121928
    • Ng SB, Bigham AW, Buckingham KJ, Hannibal MC, McMillin MJ, Gildersleeve HI, Beck AE, Tabor HK, Cooper GM, Mefford HC, Lee C, Turner EH, Smith JD, Rieder MJ, Yoshiura K, Matsumoto N, Ohta T, Niikawa N, Nickerson DA, Bamshad MJ, Shendure J
      Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome.
      20711175 Nature genetics , 2010 Sept. : 790-3 PMCID: PMC2930028
    • Ng SB, Bigham AW, Buckingham KJ, Hannibal MC, McMillin MJ, Gildersleeve HI, Beck AE, Tabor HK, Cooper GM, Mefford HC, Lee C, Turner EH, Smith JD, Rieder MJ, Yoshiura K, Matsumoto N, Ohta T, Niikawa N, Nickerson DA, Bamshad MJ, Shendure J
      Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome.
      20711175 Nature genetics , 2010 Sept. : 42(9)790-3 PMCID: PMC2930028
    • Enns GM, Bai RK, Beck AE, Wong LJ
      Molecular-clinical correlations in a family with variable tissue mitochondrial DNA T8993G mutant load.
      16546428 Molecular genetics and metabolism , 2006 Aug. : 364-71
    • Enns GM, Bai RK, Beck AE, Wong LJ
      Molecular-clinical correlations in a family with variable tissue mitochondrial DNA T8993G mutant load.
      16546428 Molecular genetics and metabolism , 2006 Aug. : 88(4)364-71
    • Beck AE, Hudgins L, Hoyme HE
      Autosomal dominant microtia and ocular coloboma: new syndrome or an extension of the oculo-auriculo-vertebral spectrum?
      15800906 American journal of medical genetics. Part A , 2005 May 1 : 359-62
    • Beck AE, Hudgins L, Hoyme HE
      Autosomal dominant microtia and ocular coloboma: new syndrome or an extension of the oculo-auriculo-vertebral spectrum?
      15800906 American journal of medical genetics. Part A , 2005 May 1 : 134(4)359-62
    • Adam MP, Manning MA, Beck AE, Kwan A, Enns GM, Clericuzio C, Hoyme HE
      Methotrexate/misoprostol embryopathy: report of four cases resulting from failed medical abortion.
      14556250 American journal of medical genetics. Part A , 2003 Nov. 15 : 72-8
    • Adam MP, Manning MA, Beck AE, Kwan A, Enns GM, Clericuzio C, Hoyme HE
      Methotrexate/misoprostol embryopathy: report of four cases resulting from failed medical abortion.
      14556250 American journal of medical genetics. Part A , 2003 Nov. 15 : 123A(1)72-8

  • Presentations Title Event Location Date
    Defects of embryonic myosin in Freeman-Sheldon syndrome cause reduced force and prolonged relaxation of skeletal myofibers Northwest Genetics Exchange Seattle, WA 2010
    Phenotypic Characterization of Familial Oculo-Auriculo-Vertebral Spectrum (OAVS) Department of Pediatrics Fellows Research Day Seattle, WA 2006
  • Grant Title Grantor Amount Award Date
    Genetic Basis of Conductive Deafness UW Institute of Translational Health Sciences $20,000 June 1, 2013 - May 31, 2014
    Identifying the Genetic and Molecular Basis of Clubfoot NIH, NICHD $635,580.00 Sept. 30, 2009

Overview

Board Certification(s)

Pediatrics
Clinical Genetics (MD)

Medical/Professional School

Washington University School of Medicine, St Louis

Residency

Pediatrics, University of California - San Francisco, San Francisco

Fellowship

Medical Biochemical Genetics, Stanford University School of Medicine, Stanford
Stanford University - Dept of Medical Genetics, Stanford
Medical Biochemical Genetics, University of Washington, Seattle