Heart and Blood Conditions

Kawasaki Disease Treatment

To reduce the risk of coronary artery problems, it's important for children with Kawasaki disease to get treatment early on.

Kawasaki Disease Treatment Options

Intravenous gamma globulin (IVIG) (a medicine given through a vein, or by IV) is the main treatment. It is effective if given within the first 10 days of the disease. About 20 percent of children do not respond to the first dose and need to get a second dose. To get this medicine, your child will need to stay in the hospital.

Your child will also need aspirin to help control symptoms like fever, rash and swollen joints. At first they will likely need high doses. Then, after their temperature is normal, the doctor will lower the dose. Your child will go home and stay on the lower dose for several weeks.

Once treatment starts, children with Kawasaki disease usually start to feel much better within about a day.

If your child has coronary artery problems from Kawasaki disease, they may need other types of care to help prevent further problems, like medicines that prevent blood clots.

New Treatments for Kawasaki Disease

Doctors at Seattle Children's are trying to find new and better treatments for Kawasaki disease. Because 20 percent of children do not respond to IVIG, they are trying different medications. Your team at the hospital may ask your permission for your child to participate in clinical research study, or clinical trial, to learn more about treating Kawasaki disease. Doctors at Seattle Children's also are searching for a way to predict which patients will not respond to IVIG. They may ask you to participate in this type of research.