Chromosomal and Genetic Conditions

Van der Woude Syndrome Symptoms and Diagnosis

Symptoms of Van der Woude Syndrome

The symptoms depend on which aspects of the van der Woude syndrome (VWS) a child is born with.

If they are born without lip pits or mounds in their lower lip, children with VWS look just like children with cleft lip and palate. The pits and mounds are different sizes in different children so they can be almost unnoticeable or quite apparent. The pits can contain saliva glands so they often look moist.

Otherwise, children with VWS look entirely normal.

Van der Woude Syndrome Diagnosis

Sometimes cleft lip and palate are diagnosed before a baby is born because the clefts can be visible during a routine ultrasound.

In many cases, cleft lip and palate are diagnosed after birth. Cleft lip will be obvious when the doctor examines your baby.

If your child has a cleft palate but not cleft lip, it may not be noticeable at first, especially if the soft tissue inside the mouth covers the gap in the roof of your child's mouth. You and your child's doctor may discover a cleft palate only after your child shows other signs, such as having a hard time feeding.

The doctor may suggest doing genetic tests to tell whether your child's cleft lip and palate are part of van der Woude syndrome or some other condition, such as velocardiofacial syndrome.