Research Grants May Lead to New Therapies for Treating Childhood Asthma

Seattle - Exercise-induced asthma, genetic immunology and ibuprofen are the subjects of research projects for which grant awards were announced today by the American Lung Association of Washington.

Seattle - Exercise-induced asthma, genetic immunology and ibuprofen are the subjects of research projects for which grant awards were announced today by the American Lung Association of Washington. The grant awards will go to fund the work of five pulmonary physicians in Seattle.

Jason Debley, MD, at Children’s Hospital and Regional Medical Center, Teal Hallstrand, MD, and David Park, MD, at Harborview Medical Center, and Jason Chien, MD, at the Fred Hutchinson Cancer Research Center, received individual research grants.

In some adults with asthma, taking aspirin or ibuprofen can trigger an asthma attack. Aspirin and ibuprofen, as well as other non-steroidal anti-inflammatory drugs, share a similar mechanism that can cause the release of biochemicals which act as powerful triggers of airways spasm in asthma attacks.

“What we don’t know is whether, like in adults, medications such as ibuprofen can worsen asthma severity in some children,” Debley, MD, said.

Debley said his study could lead to changes in national guidelines regarding use of ibuprofen in children with asthma.

The Lung Association has funded peer-reviewed research projects for physicians and other local health care professionals for over 80 years. Research started with tuberculosis many years ago and continues today with projects like those of Drs. Debley, Hallstrand, Park and Chien.

Lung Association grants are unique and valuable in that they help support emerging researchers, many of whom go on to make important discoveries and advances in treatment.

About American Lung Association of Washington

Founded in 1906, the American Lung Association of Washington’s mission is to assure lung health for the people of Washington. For more information about the Lung Association’s research program and its community health programs in tobacco control, asthma, and air quality, please call 1-800-732-9339 (Washington only) or visit our website at

About Seattle Children’s

Seattle Children’s Hospital, Foundation and Research Institute together deliver superior patient care, advance new discoveries and treatments through pediatric research, and raise funds to create better futures for patients. Consistently ranked as one of the top 10 children’s hospitals in the country by U.S. News & World Report, Seattle Children’s Hospital specializes in meeting the unique physical, emotional and developmental needs of children from infancy through young adulthood. Through the collaboration of physicians in nearly 60 pediatric subspecialties, Seattle Children’s Hospital provides inpatient, outpatient, diagnostic, surgical, rehabilitative, behavioral, and emergency and outreach services to families from around the world.

Located in downtown Seattle’s biotech corridor, Seattle Children’s Research Institute is pushing the boundaries of medical research to find cures for pediatric diseases and improve outcomes for children all over the world. Internationally recognized investigators and staff at the research institute are advancing new discoveries in cancer, genetics, immunology, pathology, infectious disease, injury prevention, bioethics and much more.

Seattle Children’s Hospital and Research Foundation and Seattle Children’s Hospital Guild Association work together to gather community support and raise funds for uncompensated care, clinical care and research. The foundation receives nearly 80,000 gifts each year, from lemonade stand proceeds to corporate sponsorships. Seattle Children’s Hospital Guild Association is the largest all-volunteer fundraising network for any hospital in the country, serving as the umbrella organization for 450 groups of people who turn an activity they love into a fundraiser. Support from the foundation and guild association makes it possible for Seattle Children’s care and research teams to improve the health and well-being of all kids.

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