As Scientists Train the Immune System to Fight Cancer, Others Look to Combat Costs

As Scientists Train the Immune System to Fight Cancer, Others Look to Combat Costs

We now know that cancer cells can be destroyed by a specialized type of white blood cell called a killer T cell. Protein engineer Cassie Bryan at the University of Washington's Institute for Protein Design is working to come up with a new, more affordable way of disrupting cancer's ability to disable T cells at the molecular level. In collaboration with oncologists from Seattle Children's Hospital and the Fred Hutch, Bryan has produced a tiny, non-antibody protein which sticks to T cells in a way that should keep PD-L1 from deactivating them.

About Seattle Children’s

Seattle Children’s mission is to provide hope, care and cures to help every child live the healthiest and most fulfilling life possible. Together, Seattle Children’s Hospital, Research Institute and Foundation deliver superior patient care, identify new discoveries and treatments through pediatric research, and raise funds to create better futures for patients.

Ranked as one of the top children’s hospitals in the country by U.S. News & World Report, Seattle Children’s serves as the pediatric and adolescent academic medical center for Washington, Alaska, Montana and Idaho – the largest region of any children’s hospital in the country. As one of the nation’s top five pediatric research centers, Seattle Children’s Research Institute is internationally recognized for its work in neurosciences, immunology, cancer, infectious disease, injury prevention and much more. Seattle Children’s Hospital and Research Foundation works with the Seattle Children’s Guild Association, the largest all-volunteer fundraising network for any hospital in the country, to gather community support and raise funds for uncompensated care and research. Join Seattle Children’s bold initiative – It Starts With Yes: The Campaign for Seattle Children’s – to transform children’s health for generations to come.

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