When two of her young patients with cystic fibrosis (CF) died within a week of each other, Dr. Bonnie Ramsey knew what she had to do.

"I couldn't continue to hold the hands of these young boys and girls without personally trying to improve the outcomes for CF."
Her dedication and spirit of inquiry have led to remarkable advances in the treatment of people with CF, helping double their average lifespan and vastly improving their quality of life.
Ramsey was a vital part of the Children's research that led to a breakthrough CF treatment: TOBI™, an inhalable form of an existing antibiotic that is delivered directly to the lungs, where it is needed most, while limiting unnecessary exposure to others parts of the body.

No one appreciates the gains from medical research more than Kari Foss, who was diagnosed with cystic fibrosis at age 2.
Kari participated in four CF studies at Children's. Not only does she feel like she's helping future CF patients, she considers it payback for the care she's received at Children's Cystic Fibrosis Clinic.
"CF sounds like such a terrible disease, but with all the research that's going on, people with CF can accomplish a lot in their lives," she says.
Thanks to breakthroughs in research, Kari's biggest challenge is fitting in treatments around her active-teenager lifestyle.
In addition to CF, Children's researchers are making major contributions to the understanding of bioethics, immunology, infectious disease, tissue response to injury, and cancer.