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Genetics Lab

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Maternal Cell Contamination - DNA Tests

In the prenatal testing scenario, there are rare occasions when the mother's cells are present in the fetal sample sent for analysis. If this occurs, the test may yield a false result. Maternal blood is therefore submitted to determine if maternal cell contamination has occurred. If maternal cells are present in the fetal sample, a new fetal sample will be required.

Test Name: Maternal Cell Contamination - DNA
Test Code:
MATCONTAM
Test Description:
11 loci on 11 different chromosomes are compared between maternal and fetal DNA.
Synonyms:
MCC
Indication:
This test is required for all prenatal tests.
Related Tests:
Clinical Links:
Availability:
Turnaround Time:
7-10 days
Methodology:
PCR
Reference Range:
Requisition:
Consent Form:
Sample Requirements: Type
Maternal whole blood: 1-3 mL in EDTA (purple top) or ACD (yellow top).

Processing
Do not spin. Refrigerate blood samples which will not be immediately shipped.

Shipping
Room temperature via overnight shipping.
Samples Received:
Mon – Fri 8:00 am – 5:00 pm PST
Special Considerations:
Sample can be sent ahead of cultured cells for prenatal testing.
Cost:
Please e-mail Lab Client Services (labclientservices@seattlechildrens.org) or call at 206-987-2617 with any billing questions
CPT Code:
Please e-mail Lab Client Services (labclientservices@seattlechildrens.org) or call at 206-987-2617 with any billing questions