Seattle Scientists First to Show Monkey Model of Zika Damage

Seattle Scientists First to Show Monkey Model of Zika Damage

Paving the way for potential treatments for Zika virus infections, Seattle scientists have become the first to demonstrate the devastating effects of the disease in a monkey, an animal that closely resembles humans. Researchers with the University of Washington Center for Innate Immunity and Immune Disease reported the first case of Zika-caused brain damage in the fetus of a nonhuman primate: a single pigtail macaque. Dr. Kristina Adams Waldorf, the UW expert who was lead author on the study published in the journal Nature Medicine, led the 32-member team behind the work, along with senior authors Dr. Lakshmi Rajagopal, an infectious-disease expert at Seattle Children’s Research Institute, and Michael Gale Jr., a UW immunologist.

About Seattle Children’s

Seattle Children’s Hospital, Foundation and Research Institute together deliver superior patient care, advance new discoveries and treatments through pediatric research, and raise funds to create better futures for patients. Consistently ranked as one of the top 10 children’s hospitals in the country by U.S. News & World Report, Seattle Children’s Hospital specializes in meeting the unique physical, emotional and developmental needs of children from infancy through young adulthood. Through the collaboration of physicians in nearly 60 pediatric subspecialties, Seattle Children’s Hospital provides inpatient, outpatient, diagnostic, surgical, rehabilitative, behavioral, and emergency and outreach services to families from around the world.

Located in downtown Seattle’s biotech corridor, Seattle Children’s Research Institute is pushing the boundaries of medical research to find cures for pediatric diseases and improve outcomes for children all over the world. Internationally recognized investigators and staff at the research institute are advancing new discoveries in cancer, genetics, immunology, pathology, infectious disease, injury prevention, bioethics and much more.

Seattle Children’s Hospital and Research Foundation and Seattle Children’s Hospital Guild Association work together to gather community support and raise funds for uncompensated care, clinical care and research. The foundation receives nearly 80,000 gifts each year, from lemonade stand proceeds to corporate sponsorships. Seattle Children’s Hospital Guild Association is the largest all-volunteer fundraising network for any hospital in the country, serving as the umbrella organization for 450 groups of people who turn an activity they love into a fundraiser. Support from the foundation and guild association makes it possible for Seattle Children’s care and research teams to improve the health and well-being of all kids.

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