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Transplant saves first ‘bubble boy’ in Wash. state detected with newborn screening

Transplant saves first ‘bubble boy’ in Wash. state detected with newborn screening

Source: On the Pulse Blog

Ezra Dixon was born April 7, four months after the state of Washington first starting screening newborns for the disorder commonly known as “bubble boy disease,” which leaves its patients at the mercy of common germs. He is the only child in the state so far diagnosed with severe combined immunodeficiency, or SCID, detected through the program. Since Ezra’s condition was detected early, he was able to receive a bone-marrow transplant from his brother Judah when he was eight weeks old. Within two weeks, healthy cells had already taken hold, offering Ezra a promising future – and underscoring the results of a new study involving Fred Hutchinson Cancer Research Center and Seattle Children’s researchers. “Regardless of what source you use for the stem cell graft, if you are transplanted at less than 3 months of age, you have a 94 percent chance of survival,” said Dr. Suzanne Skoda-Smith, clinical director for the Division of Immunology at Seattle Children’s. Skoda-Smith and her colleague, Dr. Lauri Burroughs, director of the Non-Malignant Transplant Program at the Fred Hutchinson Cancer Research Center and Seattle Children’s, were among researchers who provided data from 240 babies with SCID who received transplants at 25 centers from 2000 to 2009.

About Seattle Children’s

Seattle Children’s Hospital, Foundation and Research Institute together deliver superior patient care, advance new discoveries and treatments through pediatric research, and raise funds to create better futures for patients. Consistently ranked as one of the top 10 children’s hospitals in the country by U.S. News & World Report, Seattle Children’s Hospital specializes in meeting the unique physical, emotional and developmental needs of children from infancy through young adulthood. Through the collaboration of physicians in nearly 60 pediatric subspecialties, Seattle Children’s Hospital provides inpatient, outpatient, diagnostic, surgical, rehabilitative, behavioral, and emergency and outreach services to families from around the world.

Located in downtown Seattle’s biotech corridor, Seattle Children’s Research Institute is pushing the boundaries of medical research to find cures for pediatric diseases and improve outcomes for children all over the world. Internationally recognized investigators and staff at the research institute are advancing new discoveries in cancer, genetics, immunology, pathology, infectious disease, injury prevention, bioethics and much more.

Seattle Children’s Hospital and Research Foundation and Seattle Children’s Hospital Guild Association work together to gather community support and raise funds for uncompensated care, clinical care and research. The foundation receives nearly 80,000 gifts each year, from lemonade stand proceeds to corporate sponsorships. Seattle Children’s Hospital Guild Association is the largest all-volunteer fundraising network for any hospital in the country, serving as the umbrella organization for 450 groups of people who turn an activity they love into a fundraiser. Support from the foundation and guild association makes it possible for Seattle Children’s care and research teams to improve the health and well-being of all kids.

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