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Transplant saves first ‘bubble boy’ in Wash. state detected with newborn screening


Transplant saves first ‘bubble boy’ in Wash. state detected with newborn screening

August 13, 2014


Source - On the Pulse Blog

Ezra Dixon was born April 7, four months after the state of Washington first starting screening newborns for the disorder commonly known as “bubble boy disease,” which leaves its patients at the mercy of common germs. He is the only child in the state so far diagnosed with severe combined immunodeficiency, or SCID, detected through the program. Since Ezra’s condition was detected early, he was able to receive a bone-marrow transplant from his brother Judah when he was eight weeks old. Within two weeks, healthy cells had already taken hold, offering Ezra a promising future – and underscoring the results of a new study involving Fred Hutchinson Cancer Research Center and Seattle Children’s researchers. “Regardless of what source you use for the stem cell graft, if you are transplanted at less than 3 months of age, you have a 94 percent chance of survival,” said Dr. Suzanne Skoda-Smith, clinical director for the Division of Immunology at Seattle Children’s. Skoda-Smith and her colleague, Dr. Lauri Burroughs, director of the Non-Malignant Transplant Program at the Fred Hutchinson Cancer Research Center and Seattle Children’s, were among researchers who provided data from 240 babies with SCID who received transplants at 25 centers from 2000 to 2009.

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